BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

520 related articles for article (PubMed ID: 15509521)

  • 1. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.
    Kawaguchi T; Yoshida T; Harada M; Hisamoto T; Nagao Y; Ide T; Taniguchi E; Kumemura H; Hanada S; Maeyama M; Baba S; Koga H; Kumashiro R; Ueno T; Ogata H; Yoshimura A; Sata M
    Am J Pathol; 2004 Nov; 165(5):1499-508. PubMed ID: 15509521
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2.
    Rui L; Yuan M; Frantz D; Shoelson S; White MF
    J Biol Chem; 2002 Nov; 277(44):42394-8. PubMed ID: 12228220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.
    Shi H; Tzameli I; Bjørbaek C; Flier JS
    J Biol Chem; 2004 Aug; 279(33):34733-40. PubMed ID: 15181014
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
    Guo S; Dunn SL; White MF
    Mol Endocrinol; 2006 Dec; 20(12):3389-99. PubMed ID: 16916938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems.
    Calegari VC; Alves M; Picardi PK; Inoue RY; Franchini KG; Saad MJ; Velloso LA
    Endocrinology; 2005 Feb; 146(2):579-88. PubMed ID: 15514089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.
    Ueki K; Kondo T; Kahn CR
    Mol Cell Biol; 2004 Jun; 24(12):5434-46. PubMed ID: 15169905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.
    Senn JJ; Klover PJ; Nowak IA; Zimmers TA; Koniaris LG; Furlanetto RW; Mooney RA
    J Biol Chem; 2003 Apr; 278(16):13740-6. PubMed ID: 12560330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes.
    Aytug S; Reich D; Sapiro LE; Bernstein D; Begum N
    Hepatology; 2003 Dec; 38(6):1384-92. PubMed ID: 14647049
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype-specific mechanisms.
    Pazienza V; Clément S; Pugnale P; Conzelman S; Foti M; Mangia A; Negro F
    Hepatology; 2007 May; 45(5):1164-71. PubMed ID: 17465001
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein.
    Miyamoto H; Moriishi K; Moriya K; Murata S; Tanaka K; Suzuki T; Miyamura T; Koike K; Matsuura Y
    J Virol; 2007 Feb; 81(4):1727-35. PubMed ID: 17135326
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression.
    Miyoshi H; Fujie H; Shintani Y; Tsutsumi T; Shinzawa S; Makuuchi M; Kokudo N; Matsuura Y; Suzuki T; Miyamura T; Moriya K; Koike K
    J Hepatol; 2005 Nov; 43(5):757-63. PubMed ID: 16083990
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of SOCS-3 by resistin.
    Steppan CM; Wang J; Whiteman EL; Birnbaum MJ; Lazar MA
    Mol Cell Biol; 2005 Feb; 25(4):1569-75. PubMed ID: 15684405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.
    Kawaguchi T; Ide T; Taniguchi E; Hirano E; Itou M; Sumie S; Nagao Y; Yanagimoto C; Hanada S; Koga H; Sata M
    Am J Gastroenterol; 2007 Mar; 102(3):570-6. PubMed ID: 17222321
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
    Duan C; Yang H; White MF; Rui L
    Mol Cell Biol; 2004 Sep; 24(17):7435-43. PubMed ID: 15314154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.
    García-Monzón C; Lo Iacono O; Mayoral R; González-Rodríguez A; Miquilena-Colina ME; Lozano-Rodríguez T; García-Pozo L; Vargas-Castrillón J; Casado M; Boscá L; Valverde AM; Martín-Sanz P
    J Hepatol; 2011 Jan; 54(1):142-52. PubMed ID: 20888662
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance.
    Banerjee S; Saito K; Ait-Goughoulte M; Meyer K; Ray RB; Ray R
    J Virol; 2008 Mar; 82(6):2606-12. PubMed ID: 18160431
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Compartmentalization and insulin-induced translocations of insulin receptor substrates, phosphatidylinositol 3-kinase, and protein kinase B in rat liver.
    Balbis A; Baquiran G; Bergeron JJ; Posner BI
    Endocrinology; 2000 Nov; 141(11):4041-9. PubMed ID: 11089534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatitis C core protein impairs insulin downstream signalling and regulatory role of IGFBP-1 expression.
    Alberstein M; Zornitzki T; Zick Y; Knobler H
    J Viral Hepat; 2012 Jan; 19(1):65-71. PubMed ID: 22187946
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism.
    Li L; Grønning LM; Anderson PO; Li S; Edvardsen K; Johnston J; Kioussis D; Shepherd PR; Wang P
    J Biol Chem; 2004 Aug; 279(33):34107-14. PubMed ID: 15123678
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.