BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 15514033)

  • 1. Alterations in mitogen-activated protein kinase kinase and extracellular regulated kinase signaling in theca cells contribute to excessive androgen production in polycystic ovary syndrome.
    Nelson-Degrave VL; Wickenheisser JK; Hendricks KL; Asano T; Fujishiro M; Legro RS; Kimball SR; Strauss JF; McAllister JM
    Mol Endocrinol; 2005 Feb; 19(2):379-90. PubMed ID: 15514033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Augmented androgen production is a stable steroidogenic phenotype of propagated theca cells from polycystic ovaries.
    Nelson VL; Legro RS; Strauss JF; McAllister JM
    Mol Endocrinol; 1999 Jun; 13(6):946-57. PubMed ID: 10379893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Retinoids and retinol differentially regulate steroid biosynthesis in ovarian theca cells isolated from normal cycling women and women with polycystic ovary syndrome.
    Wickenheisser JK; Nelson-DeGrave VL; Hendricks KL; Legro RS; Strauss JF; McAllister JM
    J Clin Endocrinol Metab; 2005 Aug; 90(8):4858-65. PubMed ID: 15914525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mechanism for protein kinase C inhibition of androgen production and 17alpha-hydroxylase expression in a theca cell tumor model.
    Beshay VE; Havelock JC; Sirianni R; Ye P; Suzuki T; Rainey WE; Carr BR
    J Clin Endocrinol Metab; 2007 Dec; 92(12):4802-9. PubMed ID: 17895316
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential activity of the cytochrome P450 17alpha-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells.
    Wickenheisser JK; Quinn PG; Nelson VL; Legro RS; Strauss JF; McAllister JM
    J Clin Endocrinol Metab; 2000 Jun; 85(6):2304-11. PubMed ID: 10852468
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin augmentation of 17alpha-hydroxylase activity is mediated by phosphatidyl inositol 3-kinase but not extracellular signal-regulated kinase-1/2 in human ovarian theca cells.
    Munir I; Yen HW; Geller DH; Torbati D; Bierden RM; Weitsman SR; Agarwal SK; Magoffin DA
    Endocrinology; 2004 Jan; 145(1):175-83. PubMed ID: 14512432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dysregulation of cytochrome P450 17alpha-hydroxylase messenger ribonucleic acid stability in theca cells isolated from women with polycystic ovary syndrome.
    Wickenheisser JK; Nelson-Degrave VL; McAllister JM
    J Clin Endocrinol Metab; 2005 Mar; 90(3):1720-7. PubMed ID: 15598676
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased cytochrome P450 17alpha-hydroxylase promoter function in theca cells isolated from patients with polycystic ovary syndrome involves nuclear factor-1.
    Wickenheisser JK; Nelson-DeGrave VL; Quinn PG; McAllister JM
    Mol Endocrinol; 2004 Mar; 18(3):588-605. PubMed ID: 14684846
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The molecular phenotype of polycystic ovary syndrome (PCOS) theca cells and new candidate PCOS genes defined by microarray analysis.
    Wood JR; Nelson VL; Ho C; Jansen E; Wang CY; Urbanek M; McAllister JM; Mosselman S; Strauss JF
    J Biol Chem; 2003 Jul; 278(29):26380-90. PubMed ID: 12734205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype.
    McAllister JM; Modi B; Miller BA; Biegler J; Bruggeman R; Legro RS; Strauss JF
    Proc Natl Acad Sci U S A; 2014 Apr; 111(15):E1519-27. PubMed ID: 24706793
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Valproate potentiates androgen biosynthesis in human ovarian theca cells.
    Nelson-DeGrave VL; Wickenheisser JK; Cockrell JE; Wood JR; Legro RS; Strauss JF; McAllister JM
    Endocrinology; 2004 Feb; 145(2):799-808. PubMed ID: 14576182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Involvement of Granulosa Cells in the Regulation by Gonadotropins of
    Kakuta H; Iguchi T; Sato T
    In Vivo; 2018; 32(6):1387-1401. PubMed ID: 30348693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells.
    Schoppee PD; Garmey JC; Veldhuis JD
    Biol Reprod; 2002 Jan; 66(1):190-8. PubMed ID: 11751282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistin stimulation of 17alpha-hydroxylase activity in ovarian theca cells in vitro: relevance to polycystic ovary syndrome.
    Munir I; Yen HW; Baruth T; Tarkowski R; Azziz R; Magoffin DA; Jakimiuk AJ
    J Clin Endocrinol Metab; 2005 Aug; 90(8):4852-7. PubMed ID: 15886251
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome.
    Nelson VL; Qin KN; Rosenfield RL; Wood JR; Penning TM; Legro RS; Strauss JF; McAllister JM
    J Clin Endocrinol Metab; 2001 Dec; 86(12):5925-33. PubMed ID: 11739466
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of small interfering RNAs of cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17) on androgen biosynthesis in theca cells.
    Du J; Liang X; Zeng H; Shu Y; Yao S; Zhu B; Zhuang G
    Cell Biol Int; 2008 Apr; 32(4):469-72. PubMed ID: 18262808
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The molecular signature of polycystic ovary syndrome (PCOS) theca cells defined by gene expression profiling.
    Wood JR; Ho CK; Nelson-Degrave VL; McAllister JM; Strauss JF
    J Reprod Immunol; 2004 Aug; 63(1):51-60. PubMed ID: 15284005
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Overexpression of theca-cell messenger RNA in polycystic ovary syndrome does not correlate with polymorphisms in the cholesterol side-chain cleavage and 17alpha-hydroxylase/C(17-20) lyase promoters.
    Daneshmand S; Weitsman SR; Navab A; Jakimiuk AJ; Magoffin DA
    Fertil Steril; 2002 Feb; 77(2):274-80. PubMed ID: 11821083
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Strategies to elucidate the mechanism of excessive theca cell androgen production in PCOS.
    Strauss JF; Wood JR; Christenson LK; McAllister JM
    Mol Cell Endocrinol; 2002 Jan; 186(2):183-8. PubMed ID: 11900894
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro.
    Veldhuis JD; Zhang G; Garmey JC
    J Clin Endocrinol Metab; 2002 Mar; 87(3):1129-33. PubMed ID: 11889176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.