BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 15516695)

  • 21. C-Terminal membrane spanning region of human heme oxygenase-1 mediates a time-dependent complex formation with cytochrome P450 reductase.
    Huber Iii WJ; Scruggs BA; Backes WL
    Biochemistry; 2009 Jan; 48(1):190-7. PubMed ID: 19123922
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Relaxation kinetics of cytochrome P450 reductase: internal electron transfer is limited by conformational change and regulated by coenzyme binding.
    Gutierrez A; Paine M; Wolf CR; Scrutton NS; Roberts GC
    Biochemistry; 2002 Apr; 41(14):4626-37. PubMed ID: 11926825
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.
    Wang J; Lad L; Poulos TL; Ortiz de Montellano PR
    J Biol Chem; 2005 Jan; 280(4):2797-806. PubMed ID: 15525643
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Conformational changes of NADPH-cytochrome P450 oxidoreductase are essential for catalysis and cofactor binding.
    Xia C; Hamdane D; Shen AL; Choi V; Kasper CB; Pearl NM; Zhang H; Im SC; Waskell L; Kim JJ
    J Biol Chem; 2011 May; 286(18):16246-60. PubMed ID: 21345800
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A large-scale comparative analysis of affinity, thermodynamics and functional characteristics of interactions of twelve cytochrome P450 isoforms and their redox partners.
    Yablokov EO; Sushko TA; Ershov PV; Florinskaya AV; Gnedenko OV; Shkel TV; Grabovec IP; Strushkevich NV; Kaluzhskiy LA; Usanov SA; Gilep AA; Ivanov AS
    Biochimie; 2019 Jul; 162():156-166. PubMed ID: 31034920
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Biochemical and structural characterization of Pseudomonas aeruginosa Bfd and FPR: ferredoxin NADP+ reductase and not ferredoxin is the redox partner of heme oxygenase under iron-starvation conditions.
    Wang A; Zeng Y; Han H; Weeratunga S; Morgan BN; Moënne-Loccoz P; Schönbrunn E; Rivera M
    Biochemistry; 2007 Oct; 46(43):12198-211. PubMed ID: 17915950
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Coupled motions direct electrons along human microsomal P450 Chains.
    Pudney CR; Khara B; Johannissen LO; Scrutton NS
    PLoS Biol; 2011 Dec; 9(12):e1001222. PubMed ID: 22205878
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase.
    Gu J; Weng Y; Zhang QY; Cui H; Behr M; Wu L; Yang W; Zhang L; Ding X
    J Biol Chem; 2003 Jul; 278(28):25895-901. PubMed ID: 12697746
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Biochemical comparison of Anopheles gambiae and human NADPH P450 reductases reveals different 2'-5'-ADP and FMN binding traits.
    Lian LY; Widdowson P; McLaughlin LA; Paine MJ
    PLoS One; 2011; 6(5):e20574. PubMed ID: 21655236
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Mutations of human cytochrome P450 reductase differentially modulate heme oxygenase-1 activity and oligomerization.
    Marohnic CC; Huber Iii WJ; Patrick Connick J; Reed JR; McCammon K; Panda SP; Martásek P; Backes WL; Masters BS
    Arch Biochem Biophys; 2011 Sep; 513(1):42-50. PubMed ID: 21741353
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
    Rwere F; Xia C; Im S; Haque MM; Stuehr DJ; Waskell L; Kim JJ
    J Biol Chem; 2016 Jul; 291(28):14639-61. PubMed ID: 27189945
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Interaction of NADP(H) with oxidized and reduced P450 reductase during catalysis. Studies with nucleotide analogues.
    Murataliev MB; Feyereisen R
    Biochemistry; 2000 May; 39(17):5066-74. PubMed ID: 10819972
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Aromatic substitution of the FAD-shielding tryptophan reveals its differential role in regulating electron flux in methionine synthase reductase and cytochrome P450 reductase.
    Meints CE; Simtchouk S; Wolthers KR
    FEBS J; 2013 Mar; 280(6):1460-74. PubMed ID: 23332101
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Topological changes in the CYP3A4 active site probed with phenyldiazene: effect of interaction with NADPH-cytochrome P450 reductase and cytochrome b5 and of site-directed mutagenesis.
    Yamaguchi Y; Khan KK; He YA; He YQ; Halpert JR
    Drug Metab Dispos; 2004 Jan; 32(1):155-61. PubMed ID: 14709633
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The closed and compact domain organization of the 70-kDa human cytochrome P450 reductase in its oxidized state as revealed by NMR.
    Vincent B; Morellet N; Fatemi F; Aigrain L; Truan G; Guittet E; Lescop E
    J Mol Biol; 2012 Jul; 420(4-5):296-309. PubMed ID: 22543241
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
    Wang M; Roberts DL; Paschke R; Shea TM; Masters BS; Kim JJ
    Proc Natl Acad Sci U S A; 1997 Aug; 94(16):8411-6. PubMed ID: 9237990
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Human NADPH-P450 oxidoreductase modulates the level of cytochrome P450 CYP2D6 holoprotein via haem oxygenase-dependent and -independent pathways.
    Ding S; Yao D; Deeni YY; Burchell B; Wolf CR; Friedberg T
    Biochem J; 2001 Jun; 356(Pt 2):613-9. PubMed ID: 11368792
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Kinetic mechanism of cytochrome P450 reductase from the house fly (Musca domestica).
    Murataliev MB; Ariño A; Guzov VM; Feyereisen R
    Insect Biochem Mol Biol; 1999 Mar; 29(3):233-42. PubMed ID: 10319436
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Methene bridge carbon atom elimination in oxidative heme degradation catalyzed by heme oxygenase and NADPH-cytochrome P-450 reductase.
    Docherty JC; Firneisz GD; Schacter BA
    Arch Biochem Biophys; 1984 Dec; 235(2):657-64. PubMed ID: 6440489
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.