697 related articles for article (PubMed ID: 15518552)
1. Amino-terminal residues 1-45 of the Escherichia coli pyruvate dehydrogenase complex E1 subunit interact with the E2 subunit and are required for activity of the complex but not for reductive acetylation of the E2 subunit.
Park YH; Wei W; Zhou L; Nemeria N; Jordan F
Biochemistry; 2004 Nov; 43(44):14037-46. PubMed ID: 15518552
[TBL] [Abstract][Full Text] [Related]
2. Histidine 407, a phantom residue in the E1 subunit of the Escherichia coli pyruvate dehydrogenase complex, activates reductive acetylation of lipoamide on the E2 subunit. An explanation for conservation of active sites between the E1 subunit and transketolase.
Nemeria N; Arjunan P; Brunskill A; Sheibani F; Wei W; Yan Y; Zhang S; Jordan F; Furey W
Biochemistry; 2002 Dec; 41(52):15459-67. PubMed ID: 12501174
[TBL] [Abstract][Full Text] [Related]
3. Systematic study of the six cysteines of the E1 subunit of the pyruvate dehydrogenase multienzyme complex from Escherichia coli: none is essential for activity.
Nemeria N; Volkov A; Brown A; Yi J; Zipper L; Guest JR; Jordan F
Biochemistry; 1998 Jan; 37(3):911-22. PubMed ID: 9454581
[TBL] [Abstract][Full Text] [Related]
4. Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
Bao H; Kasten SA; Yan X; Hiromasa Y; Roche TE
Biochemistry; 2004 Oct; 43(42):13442-51. PubMed ID: 15491151
[TBL] [Abstract][Full Text] [Related]
5. Protein-protein interaction revealed by NMR T(2) relaxation experiments: the lipoyl domain and E1 component of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.
Howard MJ; Chauhan HJ; Domingo GJ; Fuller C; Perham RN
J Mol Biol; 2000 Jan; 295(4):1023-37. PubMed ID: 10656808
[TBL] [Abstract][Full Text] [Related]
6. Structural dependence of post-translational modification and reductive acetylation of the lipoyl domain of the pyruvate dehydrogenase multienzyme complex.
Wallis NG; Perham RN
J Mol Biol; 1994 Feb; 236(1):209-16. PubMed ID: 8107106
[TBL] [Abstract][Full Text] [Related]
7. Structural determinants of enzyme binding affinity: the E1 component of pyruvate dehydrogenase from Escherichia coli in complex with the inhibitor thiamin thiazolone diphosphate.
Arjunan P; Chandrasekhar K; Sax M; Brunskill A; Nemeria N; Jordan F; Furey W
Biochemistry; 2004 Mar; 43(9):2405-11. PubMed ID: 14992577
[TBL] [Abstract][Full Text] [Related]
8. Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli.
Jones DD; Horne HJ; Reche PA; Perham RN
J Mol Biol; 2000 Jan; 295(2):289-306. PubMed ID: 10623527
[TBL] [Abstract][Full Text] [Related]
9. Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
Liu S; Gong X; Yan X; Peng T; Baker JC; Li L; Robben PM; Ravindran S; Andersson LA; Cole AB; Roche TE
Arch Biochem Biophys; 2001 Feb; 386(2):123-35. PubMed ID: 11368334
[TBL] [Abstract][Full Text] [Related]
10. Expression and purification of the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase subunits of the Escherichia coli pyruvate dehydrogenase multienzyme complex: a mass spectrometric assay for reductive acetylation of dihydrolipoamide acetyltransferase.
Wei W; Li H; Nemeria N; Jordan F
Protein Expr Purif; 2003 Mar; 28(1):140-50. PubMed ID: 12651118
[TBL] [Abstract][Full Text] [Related]
11. Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex.
Fries M; Stott KM; Reynolds S; Perham RN
J Mol Biol; 2007 Feb; 366(1):132-9. PubMed ID: 17157320
[TBL] [Abstract][Full Text] [Related]
12. Phosphorylation of serine 264 impedes active site accessibility in the E1 component of the human pyruvate dehydrogenase multienzyme complex.
Seifert F; Ciszak E; Korotchkina L; Golbik R; Spinka M; Dominiak P; Sidhu S; Brauer J; Patel MS; Tittmann K
Biochemistry; 2007 May; 46(21):6277-87. PubMed ID: 17474719
[TBL] [Abstract][Full Text] [Related]
13. Characterization of point mutations in patients with pyruvate dehydrogenase deficiency: role of methionine-181, proline-188, and arginine-349 in the alpha subunit.
Tripatara A; Korotchkina LG; Patel MS
Arch Biochem Biophys; 1999 Jul; 367(1):39-50. PubMed ID: 10375397
[TBL] [Abstract][Full Text] [Related]
14. Evidence for dramatic acceleration of a C-H bond ionization rate in thiamin diphosphate enzymes by the protein environment.
Zhang S; Zhou L; Nemeria N; Yan Y; Zhang Z; Zou Y; Jordan F
Biochemistry; 2005 Feb; 44(7):2237-43. PubMed ID: 15709735
[TBL] [Abstract][Full Text] [Related]
15. Insight to the interaction of the dihydrolipoamide acetyltransferase (E2) core with the peripheral components in the Escherichia coli pyruvate dehydrogenase complex via multifaceted structural approaches.
Chandrasekhar K; Wang J; Arjunan P; Sax M; Park YH; Nemeria NS; Kumaran S; Song J; Jordan F; Furey W
J Biol Chem; 2013 May; 288(21):15402-17. PubMed ID: 23580650
[TBL] [Abstract][Full Text] [Related]
16. Recombinant expression and evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex.
Liu S; Baker JC; Andrews PC; Roche TE
Arch Biochem Biophys; 1995 Feb; 316(2):926-40. PubMed ID: 7864652
[TBL] [Abstract][Full Text] [Related]
17. 2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.
Brown A; Nemeria N; Yi J; Zhang D; Jordan WB; Machado RS; Guest JR; Jordan F
Biochemistry; 1997 Jul; 36(26):8071-81. PubMed ID: 9201955
[TBL] [Abstract][Full Text] [Related]
18. Direct kinetic evidence for half-of-the-sites reactivity in the E1 component of the human pyruvate dehydrogenase multienzyme complex through alternating sites cofactor activation.
Seifert F; Golbik R; Brauer J; Lilie H; Schröder-Tittmann K; Hinze E; Korotchkina LG; Patel MS; Tittmann K
Biochemistry; 2006 Oct; 45(42):12775-85. PubMed ID: 17042496
[TBL] [Abstract][Full Text] [Related]
19. Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex.
Jones DD; Stott KM; Reche PA; Perham RN
J Mol Biol; 2001 Jan; 305(1):49-60. PubMed ID: 11114246
[TBL] [Abstract][Full Text] [Related]
20. Recognition of a surface loop of the lipoyl domain underlies substrate channelling in the pyruvate dehydrogenase multienzyme complex.
Wallis NG; Allen MD; Broadhurst RW; Lessard IA; Perham RN
J Mol Biol; 1996 Nov; 263(3):463-74. PubMed ID: 8918601
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
