BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 15519159)

  • 1. Syntheses and bioactivities of macrocyclic paclitaxel bis-lactones.
    Liu C; Schilling JK; Ravindra R; Bane S; Kingston DG
    Bioorg Med Chem; 2004 Dec; 12(23):6147-61. PubMed ID: 15519159
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity of macrocyclic taxane analogues.
    Tarrant JG; Cook D; Fairchild C; Kadow JF; Long BH; Rose WC; Vyas D
    Bioorg Med Chem Lett; 2004 May; 14(10):2555-8. PubMed ID: 15109650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3'.
    Larroque AL; Dubois J; Thoret S; Aubert G; Guénard D; Guéritte F
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4722-6. PubMed ID: 16165352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.
    Larroque AL; Dubois J; Thoret S; Aubert G; Chiaroni A; Guéritte F; Guénard D
    Bioorg Med Chem; 2007 Jan; 15(1):563-74. PubMed ID: 17064914
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids.
    Sun L; Geng X; Geney R; Li Y; Simmerling C; Li Z; Lauher JW; Xia S; Horwitz SB; Veith JM; Pera P; Bernacki RJ; Ojima I
    J Org Chem; 2008 Dec; 73(24):9584-93. PubMed ID: 18975909
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity.
    Querolle O; Dubois J; Thoret S; Roussi F; Montiel-Smith S; Guéritte F; Guénard D
    J Med Chem; 2003 Aug; 46(17):3623-30. PubMed ID: 12904066
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and Cytotoxicity of 7,9-
    Zhao Y; Wang TE; Mills A; Gago F; Fang WS
    Molecules; 2019 Jun; 24(11):. PubMed ID: 31181726
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
    Ganesh T; Yang C; Norris A; Glass T; Bane S; Ravindra R; Banerjee A; Metaferia B; Thomas SL; Giannakakou P; Alcaraz AA; Lakdawala AS; Snyder JP; Kingston DG
    J Med Chem; 2007 Feb; 50(4):713-25. PubMed ID: 17263521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.
    Querolle O; Dubois J; Thoret S; Roussi F; Guéritte F; Guénard D
    J Med Chem; 2004 Nov; 47(24):5937-44. PubMed ID: 15537348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Short and efficient approach towards macrocyclic lactones based on a Sonogashira reaction.
    Krauss J; Unterreitmeier D; Neudert C; Bracher F
    Arch Pharm (Weinheim); 2005 Dec; 338(12):605-8. PubMed ID: 16312010
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
    Jiang J; Sun B; Wang YY; Cui M; Zhang L; Cui CZ; Wang YF; Liu XG; Lou HX
    Bioorg Med Chem; 2012 Apr; 20(7):2382-91. PubMed ID: 22365913
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
    Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
    ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel D-ring modified taxoid: synthesis and biological evaluation of a γ-lactone analogue of docetaxel.
    Gao F; Yang ZK; Chen QH; Chen XG; Wang FP
    Org Biomol Chem; 2012 Jan; 10(2):361-6. PubMed ID: 22080402
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.
    Hood KA; West LM; Rouwé B; Northcote PT; Berridge MV; Wakefield SJ; Miller JH
    Cancer Res; 2002 Jun; 62(12):3356-60. PubMed ID: 12067973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity.
    Smith AB; Sugasawa K; Atasoylu O; Yang CP; Horwitz SB
    J Med Chem; 2011 Sep; 54(18):6319-27. PubMed ID: 21870795
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Macrocyclic polyoxazoles as G-quadruplex ligands.
    Iida K; Nagasawa K
    Chem Rec; 2013 Dec; 13(6):539-48. PubMed ID: 24347328
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin.
    Winefield RD; Entwistle RA; Foland TB; Lushington GH; Himes RH
    ChemMedChem; 2008 Dec; 3(12):1844-7. PubMed ID: 18988212
    [No Abstract]   [Full Text] [Related]  

  • 18. Conformationally restricted macrocyclic analogues of combretastatins.
    Mateo C; Alvarez R; Pérez-Melero C; Peláez R; Medarde M
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6316-20. PubMed ID: 17889536
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
    Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
    Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetically E-selective macrocyclic ring-closing metathesis.
    Shen X; Nguyen TT; Koh MJ; Xu D; Speed AW; Schrock RR; Hoveyda AH
    Nature; 2017 Jan; 541(7637):380-385. PubMed ID: 28068669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.