1028 related articles for article (PubMed ID: 15519281)
1. Nrf2-Keap1 defines a physiologically important stress response mechanism.
Motohashi H; Yamamoto M
Trends Mol Med; 2004 Nov; 10(11):549-57. PubMed ID: 15519281
[TBL] [Abstract][Full Text] [Related]
2. Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism.
Velichkova M; Hasson T
Mol Cell Biol; 2005 Jun; 25(11):4501-13. PubMed ID: 15899855
[TBL] [Abstract][Full Text] [Related]
3. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.
Wakabayashi N; Itoh K; Wakabayashi J; Motohashi H; Noda S; Takahashi S; Imakado S; Kotsuji T; Otsuka F; Roop DR; Harada T; Engel JD; Yamamoto M
Nat Genet; 2003 Nov; 35(3):238-45. PubMed ID: 14517554
[TBL] [Abstract][Full Text] [Related]
4. Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.
Kobayashi A; Ohta T; Yamamoto M
Methods Enzymol; 2004; 378():273-86. PubMed ID: 15038975
[No Abstract] [Full Text] [Related]
5. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
Uruno A; Motohashi H
Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
[TBL] [Abstract][Full Text] [Related]
6. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers.
Wakabayashi N; Dinkova-Kostova AT; Holtzclaw WD; Kang MI; Kobayashi A; Yamamoto M; Kensler TW; Talalay P
Proc Natl Acad Sci U S A; 2004 Feb; 101(7):2040-5. PubMed ID: 14764894
[TBL] [Abstract][Full Text] [Related]
7. Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.
Itoh K; Tong KI; Yamamoto M
Free Radic Biol Med; 2004 May; 36(10):1208-13. PubMed ID: 15110385
[TBL] [Abstract][Full Text] [Related]
8. Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis.
Ohkoshi A; Suzuki T; Ono M; Kobayashi T; Yamamoto M
Cancer Prev Res (Phila); 2013 Feb; 6(2):149-59. PubMed ID: 23250896
[TBL] [Abstract][Full Text] [Related]
9. Effects of different exercise durations on Keap1-Nrf2-ARE pathway activation in mouse skeletal muscle.
Li T; He S; Liu S; Kong Z; Wang J; Zhang Y
Free Radic Res; 2015 Oct; 49(10):1269-74. PubMed ID: 26118597
[TBL] [Abstract][Full Text] [Related]
10. Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes.
Karapetian RN; Evstafieva AG; Abaeva IS; Chichkova NV; Filonov GS; Rubtsov YP; Sukhacheva EA; Melnikov SV; Schneider U; Wanker EE; Vartapetian AB
Mol Cell Biol; 2005 Feb; 25(3):1089-99. PubMed ID: 15657435
[TBL] [Abstract][Full Text] [Related]
11. Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.
Motohashi H; Katsuoka F; Engel JD; Yamamoto M
Proc Natl Acad Sci U S A; 2004 Apr; 101(17):6379-84. PubMed ID: 15087497
[TBL] [Abstract][Full Text] [Related]
12. Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Zhang Y; Crouch DH; Yamamoto M; Hayes JD
Biochem J; 2006 Nov; 399(3):373-85. PubMed ID: 16872277
[TBL] [Abstract][Full Text] [Related]
13. Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association.
He X; Lin GX; Chen MG; Zhang JX; Ma Q
Toxicol Sci; 2007 Jul; 98(1):298-309. PubMed ID: 17420218
[TBL] [Abstract][Full Text] [Related]
14. The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity.
Copple IM; Goldring CE; Kitteringham NR; Park BK
Toxicology; 2008 Apr; 246(1):24-33. PubMed ID: 18083283
[TBL] [Abstract][Full Text] [Related]
15. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway.
Kensler TW; Wakabayashi N; Biswal S
Annu Rev Pharmacol Toxicol; 2007; 47():89-116. PubMed ID: 16968214
[TBL] [Abstract][Full Text] [Related]
16. Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.
Kang MI; Kobayashi A; Wakabayashi N; Kim SG; Yamamoto M
Proc Natl Acad Sci U S A; 2004 Feb; 101(7):2046-51. PubMed ID: 14764898
[TBL] [Abstract][Full Text] [Related]
17. Increased Nrf2 activation in livers from Keap1-knockdown mice increases expression of cytoprotective genes that detoxify electrophiles more than those that detoxify reactive oxygen species.
Reisman SA; Yeager RL; Yamamoto M; Klaassen CD
Toxicol Sci; 2009 Mar; 108(1):35-47. PubMed ID: 19129213
[TBL] [Abstract][Full Text] [Related]
18. [Oxidative/electrophilic stress sensor Keap1 regulates the rapid turnover of transcripition factor Nrf2].
Kobayashi A; Tong KI
Tanpakushitsu Kakusan Koso; 2006 Aug; 51(10 Suppl):1304-8. PubMed ID: 16922392
[No Abstract] [Full Text] [Related]
19. Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.
Keleku-Lukwete N; Suzuki M; Otsuki A; Tsuchida K; Katayama S; Hayashi M; Naganuma E; Moriguchi T; Tanabe O; Engel JD; Imaizumi M; Yamamoto M
Proc Natl Acad Sci U S A; 2015 Sep; 112(39):12169-74. PubMed ID: 26371321
[TBL] [Abstract][Full Text] [Related]
20. Nrf2 protects against furosemide-induced hepatotoxicity.
Qu Q; Liu J; Zhou HH; Klaassen CD
Toxicology; 2014 Oct; 324():35-42. PubMed ID: 24813929
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]