BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 15522234)

  • 1. Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells.
    Gu N; Suzuki N; Takeda J; Adachi T; Tsujimoto G; Aoki N; Ishihara A; Tsuda K; Yasuda K
    Biochem Biophys Res Commun; 2004 Dec; 325(1):308-13. PubMed ID: 15522234
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.
    Okita K; Yang Q; Yamagata K; Hangenfeldt KA; Miyagawa J; Kajimoto Y; Nakajima H; Namba M; Wollheim CB; Hanafusa T; Matsuzawa Y
    Biochem Biophys Res Commun; 1999 Sep; 263(2):566-9. PubMed ID: 10491332
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure/function studies of hepatocyte nuclear factor-1alpha, a diabetes-associated transcription factor.
    Yang Q; Yamagata K; Yamamoto K; Miyagawa J; Takeda J; Iwasaki N; Iwahashi H; Yoshiuchi I; Namba M; Miyazaki J; Hanafusa T; Matsuzawa Y
    Biochem Biophys Res Commun; 1999 Dec; 266(1):196-202. PubMed ID: 10581189
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X).
    Bjørkhaug L; Ye H; Horikawa Y; Søvik O; Molven A; Njølstad PR
    Biochem Biophys Res Commun; 2000 Dec; 279(3):792-8. PubMed ID: 11162430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young.
    Ellard S
    Hum Mutat; 2000 Nov; 16(5):377-85. PubMed ID: 11058894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients.
    Godart F; Bellanné-Chantelot C; Clauin S; Gragnoli C; Abderrahmani A; Blanché H; Boutin P; Chèvre JC; Froguel P; Bailleul B
    Hum Mutat; 2000; 15(2):173-80. PubMed ID: 10649494
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
    Rose RB; Bayle JH; Endrizzi JA; Cronk JD; Crabtree GR; Alber T
    Nat Struct Biol; 2000 Sep; 7(9):744-8. PubMed ID: 10966642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of a new mutation in the hepatocyte nuclear factor-1alpha gene in a Polish family with early-onset type 2 diabetes mellitus.
    Malecki MT; Klupa T; Frey J; Cyganek K; Galicka-Stankowska D; Wanic K; Sieradzki J
    Diabetes Nutr Metab; 2001 Oct; 14(5):288-91. PubMed ID: 11806470
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.
    Wang H; Maechler P; Hagenfeldt KA; Wollheim CB
    EMBO J; 1998 Nov; 17(22):6701-13. PubMed ID: 9822613
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A low renal threshold for glucose in diabetic patients with a mutation in the hepatocyte nuclear factor-1alpha (HNF-1alpha) gene.
    Menzel R; Kaisaki PJ; Rjasanowski I; Heinke P; Kerner W; Menzel S
    Diabet Med; 1998 Oct; 15(10):816-20. PubMed ID: 9796880
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel dominant-negative mutation of the hepatocyte nuclear factor-1alpha gene in Japanese early-onset type 2 diabetes.
    Tanaka S; Kobayashi T; Tomura H; Okubo M; Nakanishi K; Takeda J; Murase T
    Horm Metab Res; 2000 Sep; 32(9):373-7. PubMed ID: 11014387
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1.
    Kristinsson SY; Thorolfsdottir ET; Talseth B; Steingrimsson E; Thorsson AV; Helgason T; Hreidarsson AB; Arngrimsson R
    Diabetologia; 2001 Nov; 44(11):2098-103. PubMed ID: 11719843
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas.
    Nammo T; Yamagata K; Hamaoka R; Zhu Q; Akiyama TE; Gonzalez FJ; Miyagawa J; Matsuzawa Y
    Diabetologia; 2002 Aug; 45(8):1142-53. PubMed ID: 12189445
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Maturity-onset diabetes of the young: from clinical description to molecular genetic characterization.
    Owen K; Hattersley AT
    Best Pract Res Clin Endocrinol Metab; 2001 Sep; 15(3):309-23. PubMed ID: 11554773
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The dimerization domain of HNF-1alpha: structure and plasticity of an intertwined four-helix bundle with application to diabetes mellitus.
    Narayana N; Hua Q; Weiss MA
    J Mol Biol; 2001 Jul; 310(3):635-58. PubMed ID: 11439029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sucrase-isomaltase gene transcription requires the hepatocyte nuclear factor-1 (HNF-1) regulatory element and is regulated by the ratio of HNF-1 alpha to HNF-1 beta.
    Boudreau F; Zhu Y; Traber PG
    J Biol Chem; 2001 Aug; 276(34):32122-8. PubMed ID: 11395488
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proposed mechanism for a novel insertion/deletion frameshift mutation (I414G415ATCG-->CCA) in the hepatocyte nuclear factor 1 alpha (HNF-1 alpha) gene which causes maturity-onset diabetes of the young (MODY).
    Ellard S; Bulman MP; Frayling TM; Shepherd M; Hattersley AT
    Hum Mutat; 2000 Sep; 16(3):273. PubMed ID: 10980542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.
    Krasinski SD; Van Wering HM; Tannemaat MR; Grand RJ
    Am J Physiol Gastrointest Liver Physiol; 2001 Jul; 281(1):G69-84. PubMed ID: 11408257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of hepatocyte nuclear factor 1alpha and 1beta in the transcriptional regulation of human dipeptidyl peptidase IV during differentiation of Caco-2 cells.
    Erickson RH; Lai RS; Kim YS
    Biochem Biophys Res Commun; 2000 Apr; 270(1):235-9. PubMed ID: 10733933
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.
    Yamagata K; Yang Q; Yamamoto K; Iwahashi H; Miyagawa J; Okita K; Yoshiuchi I; Miyazaki J; Noguchi T; Nakajima H; Namba M; Hanafusa T; Matsuzawa Y
    Diabetes; 1998 Aug; 47(8):1231-5. PubMed ID: 9703322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.