These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 15522265)

  • 1. Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential.
    Xu JJ; Diaz D; O'Brien PJ
    Chem Biol Interact; 2004 Nov; 150(1):115-28. PubMed ID: 15522265
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes.
    Nadanaciva S; Aleo MD; Strock CJ; Stedman DB; Wang H; Will Y
    Toxicol Appl Pharmacol; 2013 Oct; 272(2):272-80. PubMed ID: 23811329
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Screening for reactive intermediates and toxicity assessment in drug discovery.
    Caldwell GW; Yan Z
    Curr Opin Drug Discov Devel; 2006 Jan; 9(1):47-60. PubMed ID: 16445117
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening.
    O'Brien PJ; Irwin W; Diaz D; Howard-Cofield E; Krejsa CM; Slaughter MR; Gao B; Kaludercic N; Angeline A; Bernardi P; Brain P; Hougham C
    Arch Toxicol; 2006 Sep; 80(9):580-604. PubMed ID: 16598496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Organ slices for the evaluation of human drug toxicity.
    Vickers AE; Fisher RL
    Chem Biol Interact; 2004 Nov; 150(1):87-96. PubMed ID: 15522263
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of in vitro protein biomarkers of idiosyncratic liver toxicity.
    Gao J; Ann Garulacan L; Storm SM; Hefta SA; Opiteck GJ; Lin JH; Moulin F; Dambach DM
    Toxicol In Vitro; 2004 Aug; 18(4):533-41. PubMed ID: 15130611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human hepatocytes: isolation, cryopreservation and applications in drug development.
    Li AP
    Chem Biol Interact; 2007 May; 168(1):16-29. PubMed ID: 17270162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro assays and biomarkers for drug-induced phospholipidosis.
    Monteith DK; Morgan RE; Halstead B
    Expert Opin Drug Metab Toxicol; 2006 Oct; 2(5):687-96. PubMed ID: 17014389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes.
    Aly HA; Domènech O
    Toxicology; 2009 Aug; 262(3):175-83. PubMed ID: 19486918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells.
    Noor F; Niklas J; Müller-Vieira U; Heinzle E
    Toxicol Appl Pharmacol; 2009 Jun; 237(2):221-31. PubMed ID: 19332084
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Use and application of stem cells in toxicology.
    Davila JC; Cezar GG; Thiede M; Strom S; Miki T; Trosko J
    Toxicol Sci; 2004 Jun; 79(2):214-23. PubMed ID: 15014205
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
    Ebbels TM; Keun HC; Beckonert OP; Bollard ME; Lindon JC; Holmes E; Nicholson JK
    J Proteome Res; 2007 Nov; 6(11):4407-22. PubMed ID: 17915905
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro methods in human drug biotransformation research: implications for cancer chemotherapy.
    Hariparsad N; Sane RS; Strom SC; Desai PB
    Toxicol In Vitro; 2006 Mar; 20(2):135-53. PubMed ID: 16359840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase.
    Natalie M; Margino S; Erik H; Annelieke P; Geert V; Philippe V
    Toxicol In Vitro; 2009 Mar; 23(2):217-26. PubMed ID: 19101623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: a preliminary study using a multiplexing approach.
    Gerets HH; Hanon E; Cornet M; Dhalluin S; Depelchin O; Canning M; Atienzar FA
    Toxicol In Vitro; 2009 Mar; 23(2):319-32. PubMed ID: 19110050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Predictive value of in vitro safety studies.
    Suter W
    Curr Opin Chem Biol; 2006 Aug; 10(4):362-6. PubMed ID: 16815733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Predictive toxicogenomics in preclinical discovery.
    Barros SA; Martin RB
    Methods Mol Biol; 2008; 460():89-112. PubMed ID: 18449484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA.
    Clark RD; Wolohan PR; Hodgkin EE; Kelly JH; Sussman NL
    J Mol Graph Model; 2004 Jul; 22(6):487-97. PubMed ID: 15182808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In silico toxicology for the pharmaceutical sciences.
    Valerio LG
    Toxicol Appl Pharmacol; 2009 Dec; 241(3):356-70. PubMed ID: 19716836
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.