These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 1552498)

  • 21. Synthesis and optimization of novel (3S,5R)-5-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)piperidine-3-carboxamides as orally active renin inhibitors.
    Mori Y; Ogawa Y; Mochizuki A; Nakamura Y; Fujimoto T; Sugita C; Miyazaki S; Tamaki K; Nagayama T; Nagai Y; Inoue S; Chiba K; Nishi T
    Bioorg Med Chem; 2013 Sep; 21(18):5907-22. PubMed ID: 23886807
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Syntheses and biological activities of renin inhibitors containing statine analogues.
    Nishi T; Saito F; Nagahori H; Kataoka M; Morisawa Y; Yabe Y; Sakurai M; Higashida S; Shoji M; Matsushita Y
    Chem Pharm Bull (Tokyo); 1990 Jan; 38(1):103-9. PubMed ID: 2110866
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Renin inhibitors. Dipeptide analogues of angiotensinogen incorporating transition-state, nonpeptidic replacements at the scissile bond.
    Bolis G; Fung AK; Greer J; Kleinert HD; Marcotte PA; Perun TJ; Plattner JJ; Stein HH
    J Med Chem; 1987 Oct; 30(10):1729-37. PubMed ID: 3309313
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Statine-containing dipeptide and tripeptide inhibitors of human renin.
    Kokubu T; Hiwada K; Nagae A; Murakami E; Morisawa Y; Yabe Y; Koike H; Iijima Y
    Hypertension; 1986 Jun; 8(6 Pt 2):II1-5. PubMed ID: 3087874
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Highly potent, orally active diester macrocyclic human renin inhibitors.
    Weber AE; Steiner MG; Krieter PA; Colletti AE; Tata JR; Halgren TA; Ball RG; Doyle JJ; Schorn TW; Stearns RA
    J Med Chem; 1992 Oct; 35(21):3755-73. PubMed ID: 1433190
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Renin inhibitors. II. Synthesis and structure-activity relationships of N-terminus modified inhibitors containing a homostatine analogue.
    Atsuumi S; Nakano M; Koike Y; Tanaka S; Funabashi H; Matsuyama K; Nakano M; Sawasaki Y; Funabashi K; Morishima H
    Chem Pharm Bull (Tokyo); 1992 Dec; 40(12):3214-21. PubMed ID: 1294323
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis of novel inhibitors of the HIV-1 protease: difunctional enols of simple N-protected amino acids.
    Vaillancourt M; Vanasse B; Le Berre N; Cohen E; Sauvé G
    Bioorg Med Chem; 1994 May; 2(5):343-55. PubMed ID: 7922146
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural modification of the P2' position of 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: the discovery of aliskiren, a potent nonpeptide human renin inhibitor active after once daily dosing in marmosets.
    Maibaum J; Stutz S; Göschke R; Rigollier P; Yamaguchi Y; Cumin F; Rahuel J; Baum HP; Cohen NC; Schnell CR; Fuhrer W; Gruetter MG; Schilling W; Wood JM
    J Med Chem; 2007 Oct; 50(20):4832-44. PubMed ID: 17824680
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel 2,7-dialkyl-substituted 5(S)-amino-4(S)-hydroxy-8-phenyl-octanecarboxamide transition state peptidomimetics are potent and orally active inhibitors of human renin.
    Göschke R; Stutz S; Rasetti V; Cohen NC; Rahuel J; Rigollier P; Baum HP; Forgiarini P; Schnell CR; Wagner T; Gruetter MG; Fuhrer W; Schilling W; Cumin F; Wood JM; Maibaum J
    J Med Chem; 2007 Oct; 50(20):4818-31. PubMed ID: 17824679
    [TBL] [Abstract][Full Text] [Related]  

  • 30. alpha-Hydroxy phosphinyl-based inhibitors of human renin.
    Patel DV; Rielly-Gauvin K; Ryono DE; Free CA; Rogers WL; Smith SA; DeForrest JM; Oehl RS; Petrillo EW
    J Med Chem; 1995 Oct; 38(22):4557-69. PubMed ID: 7473584
    [TBL] [Abstract][Full Text] [Related]  

  • 31. New inhibitors of renin that contain novel phosphostatine Leu-Val replacements.
    Dellaria JF; Maki RG; Stein HH; Cohen J; Whittern D; Marsh K; Hoffman DJ; Plattner JJ; Perun TJ
    J Med Chem; 1990 Feb; 33(2):534-42. PubMed ID: 2105396
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.
    Boger J; Payne LS; Perlow DS; Lohr NS; Poe M; Blaine EH; Ulm EH; Schorn TW; LaMont BI; Lin TY
    J Med Chem; 1985 Dec; 28(12):1779-90. PubMed ID: 3906131
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Novel renin inhibitors containing analogues of statine retro-inverted at the C-termini: specificity at the P2 histidine site.
    Rosenberg SH; Plattner JJ; Woods KW; Stein HH; Marcotte PA; Cohen J; Perun TJ
    J Med Chem; 1987 Jul; 30(7):1224-8. PubMed ID: 3298652
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin infused rat model and in conscious sodium-depleted monkeys.
    Thaisrivongs S; Pals DT; DuCharme DW; Turner SR; DeGraaf GL; Lawson JA; Couch SJ; Williams MV
    J Med Chem; 1991 Feb; 34(2):633-42. PubMed ID: 1995887
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A pharmacodynamic study of the renin inhibitor SR 43,845, administered intratracheally in conscious cynomolgus monkeys.
    Lacour C; Roccon A; Cazaubon C; Richaud JP; Segondy D; Nisato D
    J Hypertens Suppl; 1991 Dec; 9(6):S384-5. PubMed ID: 1819002
    [No Abstract]   [Full Text] [Related]  

  • 36. Water-soluble renin inhibitors: design of a subnanomolar inhibitor with a prolonged duration of action.
    Rosenberg SH; Woods KW; Sham HL; Kleinert HD; Martin DL; Stein H; Cohen J; Egan DA; Bopp B; Merits I
    J Med Chem; 1990 Jul; 33(7):1962-9. PubMed ID: 2194033
    [TBL] [Abstract][Full Text] [Related]  

  • 37. An orally active renin inhibitor: cyclohexylnorstatine-containing dipeptide (KRI-1314).
    Miyazaki M; Etoh Y; Iizuka K; Toda N
    J Hypertens Suppl; 1989 Apr; 7(2):S25-7. PubMed ID: 2666609
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo.
    Thaisrivongs S; Pals DT; Harris DW; Kati WM; Turner SR
    J Med Chem; 1986 Oct; 29(10):2088-93. PubMed ID: 3531518
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Optimization and in vivo evaluations of a series of small, potent, and specific renin inhibitors containing a novel Leu-Val replacement.
    Dellaria JF; Maki RG; Bopp BA; Cohen J; Kleinert HD; Luly JR; Merits I; Plattner JJ; Stein HH
    J Med Chem; 1987 Nov; 30(11):2137-44. PubMed ID: 3118024
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A novel nonpeptidic, orally active renin inhibitor.
    Morishima H; Koike Y; Nakano M; Atsuumi S; Tanaka S; Funabashi H; Hashimoto J; Sawasaki Y; Mino N; Nakano M
    Biochem Biophys Res Commun; 1989 Mar; 159(3):999-1005. PubMed ID: 2495004
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.