BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 1552500)

  • 61. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A; Rao MP; Das P; Swapna P; Polepalli S; Nimbarte VD; Mullagiri K; Kovvuri J; Jain N
    ChemMedChem; 2014 Jul; 9(7):1463-75. PubMed ID: 24715721
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR; Rhodes MR; Herald DL; Hamel E; Schmidt JM; Pettit RK
    J Med Chem; 2005 Jun; 48(12):4087-99. PubMed ID: 15943482
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Synthesis and biological evaluation of enantiomerically pure cyclopropyl analogues of combretastatin A4.
    Ty N; Pontikis R; Chabot GG; Devillers E; Quentin L; Bourg S; Florent JC
    Bioorg Med Chem; 2013 Mar; 21(5):1357-66. PubMed ID: 23369686
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
    Gwaltney SL; Imade HM; Barr KJ; Li Q; Gehrke L; Credo RB; Warner RB; Lee JY; Kovar P; Wang J; Nukkala MA; Zielinski NA; Frost D; Ng SC; Sham HL
    Bioorg Med Chem Lett; 2001 Apr; 11(7):871-4. PubMed ID: 11294380
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Synthesis and biological evaluation of boronic acid containing cis-stilbenes as apoptotic tubulin polymerization inhibitors.
    Nakamura H; Kuroda H; Saito H; Suzuki R; Yamori T; Maruyama K; Haga T
    ChemMedChem; 2006 Jul; 1(7):729-40. PubMed ID: 16902927
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Novel imidazole-based combretastatin A-4 analogues: evaluation of their in vitro antitumor activity and molecular modeling study of their binding to the colchicine site of tubulin.
    Bellina F; Cauteruccio S; Monti S; Rossi R
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5757-62. PubMed ID: 16950621
    [TBL] [Abstract][Full Text] [Related]  

  • 67. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Development of combretastatins as potent tubulin polymerization inhibitors.
    Bukhari SNA; Kumar GB; Revankar HM; Qin HL
    Bioorg Chem; 2017 Jun; 72():130-147. PubMed ID: 28460355
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Oxazole-Bridged Combretastatin A-4 Derivatives with Tethered Hydroxamic Acids: Structure⁻Activity Relations of New Inhibitors of HDAC and/or Tubulin Function.
    Schmitt F; Gosch LC; Dittmer A; Rothemund M; Mueller T; Schobert R; Biersack B; Volkamer A; Höpfner M
    Int J Mol Sci; 2019 Jan; 20(2):. PubMed ID: 30658435
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Microtubule-disrupting effects of gallium chloride in vitro.
    Perchellet EM; Ladesich JB; Collery P; Perchellet JP
    Anticancer Drugs; 1999 Jun; 10(5):477-88. PubMed ID: 10477168
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
    Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
    Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Design, synthesis and biological evaluation of dihydronaphthalene and benzosuberene analogs of the combretastatins as inhibitors of tubulin polymerization in cancer chemotherapy.
    Sriram M; Hall JJ; Grohmann NC; Strecker TE; Wootton T; Franken A; Trawick ML; Pinney KG
    Bioorg Med Chem; 2008 Sep; 16(17):8161-71. PubMed ID: 18722127
    [TBL] [Abstract][Full Text] [Related]  

  • 73. [Natural organic compounds that affect to microtubule functions: syntheses and structure-activity relationships of combretastatins, curacin A and their analogs as the colchicine-site ligands on tubulin].
    Iwasaki S; Shirai R
    Yakugaku Zasshi; 2000 Oct; 120(10):875-89. PubMed ID: 11082700
    [TBL] [Abstract][Full Text] [Related]  

  • 74. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.
    Naret T; Bignon J; Bernadat G; Benchekroun M; Levaique H; Lenoir C; Dubois J; Pruvost A; Saller F; Borgel D; Manoury B; Leblais V; Darrigrand R; Apcher S; Brion JD; Schmitt E; Leroux FR; Alami M; Hamze A
    Eur J Med Chem; 2018 Jan; 143():473-490. PubMed ID: 29202409
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents.
    O'Boyle NM; Carr M; Greene LM; Bergin O; Nathwani SM; McCabe T; Lloyd DG; Zisterer DM; Meegan MJ
    J Med Chem; 2010 Dec; 53(24):8569-84. PubMed ID: 21080725
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Design, Synthesis, Cytotoxic Evaluation and Molecular Docking of New Fluoroquinazolinones as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.
    Zayed MF; Ahmed S; Ihmaid S; Ahmed HEA; Rateb HS; Ibrahim SRM
    Int J Mol Sci; 2018 Jun; 19(6):. PubMed ID: 29891789
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Synthesis and evaluation of double bond substituted combretastatins.
    Hadfield JA; Gaukroger K; Hirst N; Weston AP; Lawrence NJ; McGown AT
    Eur J Med Chem; 2005 Jun; 40(6):529-41. PubMed ID: 15922837
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly.
    Ducki S; Mackenzie G; Lawrence NJ; Snyder JP
    J Med Chem; 2005 Jan; 48(2):457-65. PubMed ID: 15658859
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H; Ishii Y; Hirano T; Stoiber T; Camacho Gomez JA; Schmidt P; Düssmann H; Burger AM; Prehn JH; Günther EG; Unger E; Umezawa K
    J Med Chem; 2003 Jul; 46(15):3382-94. PubMed ID: 12852768
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers.
    Lawrence NJ; Rennison D; Woo M; McGown AT; Hadfield JA
    Bioorg Med Chem Lett; 2001 Jan; 11(1):51-4. PubMed ID: 11140732
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.