BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1193 related articles for article (PubMed ID: 15533933)

  • 21. A positive role for c-Abl in Atm and Atr activation in DNA damage response.
    Wang X; Zeng L; Wang J; Chau JF; Lai KP; Jia D; Poonepalli A; Hande MP; Liu H; He G; He L; Li B
    Cell Death Differ; 2011 Jan; 18(1):5-15. PubMed ID: 20798688
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species.
    Kurz EU; Douglas P; Lees-Miller SP
    J Biol Chem; 2004 Dec; 279(51):53272-81. PubMed ID: 15489221
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
    Wang H; Guan J; Wang H; Perrault AR; Wang Y; Iliakis G
    Cancer Res; 2001 Dec; 61(23):8554-63. PubMed ID: 11731442
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A; Singh RP; Agarwal C; Siriwardana S; Sclafani RA; Agarwal R
    Carcinogenesis; 2005 Nov; 26(11):1978-87. PubMed ID: 15975956
    [TBL] [Abstract][Full Text] [Related]  

  • 25. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.
    Lu X; Nannenga B; Donehower LA
    Genes Dev; 2005 May; 19(10):1162-74. PubMed ID: 15870257
    [TBL] [Abstract][Full Text] [Related]  

  • 26. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Yan T; Desai AB; Jacobberger JW; Sramkoski RM; Loh T; Kinsella TJ
    Mol Cancer Ther; 2004 Sep; 3(9):1147-57. PubMed ID: 15367709
    [TBL] [Abstract][Full Text] [Related]  

  • 27. DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.
    Yajima H; Lee KJ; Zhang S; Kobayashi J; Chen BP
    J Mol Biol; 2009 Jan; 385(3):800-10. PubMed ID: 19071136
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ATM-dependent CHK2 activation induced by anticancer agent, irofulven.
    Wang J; Wiltshire T; Wang Y; Mikell C; Burks J; Cunningham C; Van Laar ES; Waters SJ; Reed E; Wang W
    J Biol Chem; 2004 Sep; 279(38):39584-92. PubMed ID: 15269203
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Biochemical and cellular characterization of VRX0466617, a novel and selective inhibitor for the checkpoint kinase Chk2.
    Carlessi L; Buscemi G; Larson G; Hong Z; Wu JZ; Delia D
    Mol Cancer Ther; 2007 Mar; 6(3):935-44. PubMed ID: 17363488
    [TBL] [Abstract][Full Text] [Related]  

  • 30. NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sites.
    Ray A; Milum K; Battu A; Wani G; Wani AA
    DNA Repair (Amst); 2013 Apr; 12(4):273-83. PubMed ID: 23422745
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.
    Tomimatsu N; Mukherjee B; Burma S
    EMBO Rep; 2009 Jun; 10(6):629-35. PubMed ID: 19444312
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
    Palii SS; Cui Y; Innes CL; Paules RS
    Cell Cycle; 2013 Apr; 12(7):1105-18. PubMed ID: 23462183
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
    Lee HJ; Hwang HI; Jang YJ
    Cell Cycle; 2010 Jun; 9(12):2389-98. PubMed ID: 20581453
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells.
    Furusawa Y; Iizumi T; Fujiwara Y; Hassan MA; Tabuchi Y; Nomura T; Kondo T
    Ultrason Sonochem; 2012 Nov; 19(6):1246-51. PubMed ID: 22571845
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.
    Zhang X; Succi J; Feng Z; Prithivirajsingh S; Story MD; Legerski RJ
    Mol Cell Biol; 2004 Oct; 24(20):9207-20. PubMed ID: 15456891
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.
    Chan DW; Son SC; Block W; Ye R; Khanna KK; Wold MS; Douglas P; Goodarzi AA; Pelley J; Taya Y; Lavin MF; Lees-Miller SP
    J Biol Chem; 2000 Mar; 275(11):7803-10. PubMed ID: 10713094
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Lycopene inhibits Helicobacter pylori-induced ATM/ATR-dependent DNA damage response in gastric epithelial AGS cells.
    Jang SH; Lim JW; Morio T; Kim H
    Free Radic Biol Med; 2012 Feb; 52(3):607-615. PubMed ID: 22178412
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
    Lindsey-Boltz LA; Sancar A
    J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Rapid activation of ATR by ionizing radiation requires ATM and Mre11.
    Myers JS; Cortez D
    J Biol Chem; 2006 Apr; 281(14):9346-50. PubMed ID: 16431910
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 60.