BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

578 related articles for article (PubMed ID: 15534000)

  • 21. Antigen-induced cell death of T effector cells in vitro proceeds via the Fas pathway, requires endogenous interferon-gamma and is independent of perforin and granzymes.
    Sobek V; Balkow S; Körner H; Simon MM
    Eur J Immunol; 2002 Sep; 32(9):2490-9. PubMed ID: 12207333
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.
    Pardo J; Wallich R; Ebnet K; Iden S; Zentgraf H; Martin P; Ekiciler A; Prins A; Müllbacher A; Huber M; Simon MM
    Cell Death Differ; 2007 Oct; 14(10):1768-79. PubMed ID: 17599099
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation.
    Choy JC; Hung VH; Hunter AL; Cheung PK; Motyka B; Goping IS; Sawchuk T; Bleackley RC; Podor TJ; McManus BM; Granville DJ
    Arterioscler Thromb Vasc Biol; 2004 Dec; 24(12):2245-50. PubMed ID: 15472125
    [TBL] [Abstract][Full Text] [Related]  

  • 24. DNA fragmentation induced by cytotoxic T lymphocytes can result in target cell death.
    Helgason CD; Shi L; Greenberg AH; Shi Y; Bromley P; Cotter TG; Green DR; Bleackley RC
    Exp Cell Res; 1993 Jun; 206(2):302-10. PubMed ID: 8500550
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Killing of target cells by redirected granzyme B in the absence of perforin.
    Kurschus FC; Kleinschmidt M; Fellows E; Dornmair K; Rudolph R; Lilie H; Jenne DE
    FEBS Lett; 2004 Mar; 562(1-3):87-92. PubMed ID: 15044006
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis.
    Martinvalet D; Zhu P; Lieberman J
    Immunity; 2005 Mar; 22(3):355-70. PubMed ID: 15780992
    [TBL] [Abstract][Full Text] [Related]  

  • 27. In vivo rejection of tumor cells dependent on CD8 cells that kill independently of perforin and FasL.
    Lee SH; Bar-Haim E; Machlenkin A; Goldberger O; Volovitz I; Vadai E; Tzehoval E; Eisenbach L
    Cancer Gene Ther; 2004 Mar; 11(3):237-48. PubMed ID: 14739939
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Granzyme B and the downstream granzymes C and/or F are important for cytotoxic lymphocyte functions.
    Revell PA; Grossman WJ; Thomas DA; Cao X; Behl R; Ratner JA; Lu ZH; Ley TJ
    J Immunol; 2005 Feb; 174(4):2124-31. PubMed ID: 15699143
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Stably transfected antisense granzyme B and perforin constructs inhibit human granule-mediated lytic ability.
    Bochan MR; Goebel WS; Brahmi Z
    Cell Immunol; 1995 Sep; 164(2):234-9. PubMed ID: 7656332
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A role for heat shock protein 27 in CTL-mediated cell death.
    Beresford PJ; Jaju M; Friedman RS; Yoon MJ; Lieberman J
    J Immunol; 1998 Jul; 161(1):161-7. PubMed ID: 9647220
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human and mouse granzyme A induce a proinflammatory cytokine response.
    Metkar SS; Menaa C; Pardo J; Wang B; Wallich R; Freudenberg M; Kim S; Raja SM; Shi L; Simon MM; Froelich CJ
    Immunity; 2008 Nov; 29(5):720-33. PubMed ID: 18951048
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activated T killer cells induce apoptosis in lung epithelial cells and the release of pro-inflammatory cytokine TNF-alpha.
    Shinbori T; Walczak H; Krammer PH
    Eur J Immunol; 2004 Jun; 34(6):1762-70. PubMed ID: 15162447
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis.
    Zhang D; Beresford PJ; Greenberg AH; Lieberman J
    Proc Natl Acad Sci U S A; 2001 May; 98(10):5746-51. PubMed ID: 11331782
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Perforin and granzyme B of cytotoxic T lymphocyte mediate apoptosis irrespective of Helicobacter pylori infection: possible act as a trigger of peptic ulcer formation.
    Ohara T; Morishita T; Suzuki H; Masaoka T; Ishii H
    Hepatogastroenterology; 2003; 50(54):1774-9. PubMed ID: 14696402
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
    Trapani JA; Sutton VR; Thia KY; Li YQ; Froelich CJ; Jans DA; Sandrin MS; Browne KA
    J Cell Biol; 2003 Jan; 160(2):223-33. PubMed ID: 12538642
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The role of granzyme B cluster proteases in cell-mediated cytotoxicity.
    Pham CT; Ley TJ
    Semin Immunol; 1997 Apr; 9(2):127-33. PubMed ID: 9194223
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli.
    Garcia-Sanz JA; Velotti F; MacDonald HR; Masson D; Tschopp J; Nabholz M
    Immunology; 1988 May; 64(1):129-34. PubMed ID: 3260214
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Arrest of the cell cycle reduces susceptibility of target cells to perforin-mediated lysis.
    De Leon M; Jackson KM; Cavanaugh JR; Mbangkollo D; Verret CR
    J Cell Biochem; 1998 Jun; 69(4):425-35. PubMed ID: 9620169
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dimethyl 2,2-dichlorovinyl phosphate (DDVP) markedly inhibits activities of natural killer cells, cytotoxic T lymphocytes and lymphokine-activated killer cells via the Fas-ligand/Fas pathway in perforin-knockout (PKO) mice.
    Li Q; Nakadai A; Takeda K; Kawada T
    Toxicology; 2004 Nov; 204(1):41-50. PubMed ID: 15369847
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Lytic reaction of in vivo primed peritoneal exudate CTL. Induction of high-conductance single channels in the target cell membrane.
    Lavy R; Mika YH; Rosen D; Berke G; Binah O
    J Immunol; 1995 May; 154(10):5039-48. PubMed ID: 7537299
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 29.