These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 15542838)

  • 1. Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.
    Deming PB; Schafer ZT; Tashker JS; Potts MB; Deshmukh M; Kornbluth S
    Mol Cell Biol; 2004 Dec; 24(23):10289-99. PubMed ID: 15542838
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW; Chong SY; Kim JY; Eom JI; Jeung HK; Maeng HY; Lee ST; Min YH
    Clin Cancer Res; 2003 Oct; 9(13):5018-27. PubMed ID: 14581377
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.
    Twiddy D; Brown DG; Adrain C; Jukes R; Martin SJ; Cohen GM; MacFarlane M; Cain K
    J Biol Chem; 2004 May; 279(19):19665-82. PubMed ID: 14993223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3.
    Amarante-Mendes GP; Naekyung Kim C; Liu L; Huang Y; Perkins CL; Green DR; Bhalla K
    Blood; 1998 Mar; 91(5):1700-5. PubMed ID: 9473236
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis.
    Perkins CL; Fang G; Kim CN; Bhalla KN
    Cancer Res; 2000 Mar; 60(6):1645-53. PubMed ID: 10749135
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L).
    Perkins C; Kim CN; Fang G; Bhalla KN
    Blood; 2000 Feb; 95(3):1014-22. PubMed ID: 10648417
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.
    Martin MC; Allan LA; Lickrish M; Sampson C; Morrice N; Clarke PR
    J Biol Chem; 2005 Apr; 280(15):15449-55. PubMed ID: 15703181
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.
    Lauber K; Appel HA; Schlosser SF; Gregor M; Schulze-Osthoff K; Wesselborg S
    J Biol Chem; 2001 Aug; 276(32):29772-81. PubMed ID: 11387322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.
    Steel R; Doherty JP; Buzzard K; Clemons N; Hawkins CJ; Anderson RL
    J Biol Chem; 2004 Dec; 279(49):51490-9. PubMed ID: 15371421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of the inhibitor of apoptosis protein survivin sensitizes Bcr-abl-positive cells to STI571-induced apoptosis.
    Wang Z; Sampath J; Fukuda S; Pelus LM
    Cancer Res; 2005 Sep; 65(18):8224-32. PubMed ID: 16166298
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis.
    Hu Y; Benedict MA; Ding L; Núñez G
    EMBO J; 1999 Jul; 18(13):3586-95. PubMed ID: 10393175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells.
    Mao X; Yu CR; Li WH; Li WX
    Cell Res; 2008 Aug; 18(8):879-88. PubMed ID: 18663379
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Negative regulation of the Apaf-1 apoptosome by Hsp70.
    Saleh A; Srinivasula SM; Balkir L; Robbins PD; Alnemri ES
    Nat Cell Biol; 2000 Aug; 2(8):476-83. PubMed ID: 10934467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome.
    Beere HM; Wolf BB; Cain K; Mosser DD; Mahboubi A; Kuwana T; Tailor P; Morimoto RI; Cohen GM; Green DR
    Nat Cell Biol; 2000 Aug; 2(8):469-75. PubMed ID: 10934466
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduction of caspase-8 and -9 cleavage is associated with increased c-FLIP and increased binding of Apaf-1 and Hsp70 after neonatal hypoxic/ischemic injury in mice overexpressing Hsp70.
    Matsumori Y; Northington FJ; Hong SM; Kayama T; Sheldon RA; Vexler ZS; Ferriero DM; Weinstein PR; Liu J
    Stroke; 2006 Feb; 37(2):507-12. PubMed ID: 16397188
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apaf-1 is a mediator of E2F-1-induced apoptosis.
    Furukawa Y; Nishimura N; Furukawa Y; Satoh M; Endo H; Iwase S; Yamada H; Matsuda M; Kano Y; Nakamura M
    J Biol Chem; 2002 Oct; 277(42):39760-8. PubMed ID: 12149244
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrially localized active caspase-9 and caspase-3 result mostly from translocation from the cytosol and partly from caspase-mediated activation in the organelle. Lack of evidence for Apaf-1-mediated procaspase-9 activation in the mitochondria.
    Chandra D; Tang DG
    J Biol Chem; 2003 May; 278(19):17408-20. PubMed ID: 12611882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation.
    Saleh A; Srinivasula SM; Acharya S; Fishel R; Alnemri ES
    J Biol Chem; 1999 Jun; 274(25):17941-5. PubMed ID: 10364241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.
    Kim HE; Du F; Fang M; Wang X
    Proc Natl Acad Sci U S A; 2005 Dec; 102(49):17545-50. PubMed ID: 16251271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9.
    Benedict MA; Hu Y; Inohara N; Núñez G
    J Biol Chem; 2000 Mar; 275(12):8461-8. PubMed ID: 10722681
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.