BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

395 related articles for article (PubMed ID: 15545401)

  • 1. Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
    Wang SY; Mitchell J; Moczydlowski E; Wang GK
    J Gen Physiol; 2004 Dec; 124(6):691-701. PubMed ID: 15545401
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preferential block of inactivation-deficient Na+ currents by capsaicin reveals a non-TRPV1 receptor within the Na+ channel.
    Wang SY; Mitchell J; Wang GK
    Pain; 2007 Jan; 127(1-2):73-83. PubMed ID: 16962240
    [TBL] [Abstract][Full Text] [Related]  

  • 3. State-dependent block of wild-type and inactivation-deficient Na+ channels by flecainide.
    Wang GK; Russell C; Wang SY
    J Gen Physiol; 2003 Sep; 122(3):365-74. PubMed ID: 12913091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysine point mutations in Na+ channel D4-S6 reduce inactivated channel block by local anesthetics.
    Wright SN; Wang SY; Wang GK
    Mol Pharmacol; 1998 Oct; 54(4):733-9. PubMed ID: 9765517
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isoform-specific lidocaine block of sodium channels explained by differences in gating.
    Nuss HB; Kambouris NG; Marbán E; Tomaselli GF; Balser JR
    Biophys J; 2000 Jan; 78(1):200-10. PubMed ID: 10620286
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity.
    Hanck DA; Nikitina E; McNulty MM; Fozzard HA; Lipkind GM; Sheets MF
    Circ Res; 2009 Aug; 105(5):492-9. PubMed ID: 19661462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. State-dependent block of Na+ channels by articaine via the local anesthetic receptor.
    Wang GK; Calderon J; Jaw SJ; Wang SY
    J Membr Biol; 2009 May; 229(1):1-9. PubMed ID: 19418088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.
    Wang GK; Calderon J; Wang SY
    Mol Pharmacol; 2008 Mar; 73(3):940-8. PubMed ID: 18079277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional consequences of lidocaine binding to slow-inactivated sodium channels.
    Balser JR; Nuss HB; Romashko DN; Marban E; Tomaselli GF
    J Gen Physiol; 1996 May; 107(5):643-58. PubMed ID: 8740377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. State-dependent block of voltage-gated Na+ channels by amitriptyline via the local anesthetic receptor and its implication for neuropathic pain.
    Wang GK; Russell C; Wang SY
    Pain; 2004 Jul; 110(1-2):166-74. PubMed ID: 15275764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels.
    Balser JR; Nuss HB; Orias DW; Johns DC; Marban E; Tomaselli GF; Lawrence JH
    J Clin Invest; 1996 Dec; 98(12):2874-86. PubMed ID: 8981936
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Time-dependent block and resurgent tail currents induced by mouse beta4(154-167) peptide in cardiac Na+ channels.
    Wang GK; Edrich T; Wang SY
    J Gen Physiol; 2006 Mar; 127(3):277-89. PubMed ID: 16505148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity.
    Wright SN; Wang SY; Kallen RG; Wang GK
    Biophys J; 1997 Aug; 73(2):779-88. PubMed ID: 9251794
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.
    Wang SY; Nau C; Wang GK
    Biophys J; 2000 Sep; 79(3):1379-87. PubMed ID: 10969000
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Altered gating and local anesthetic block mediated by residues in the I-S6 and II-S6 transmembrane segments of voltage-dependent Na+ channels.
    Kondratiev A; Tomaselli GF
    Mol Pharmacol; 2003 Sep; 64(3):741-52. PubMed ID: 12920212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequency and voltage-dependent inhibition of type IIA Na+ channels, expressed in a mammalian cell line, by local anesthetic, antiarrhythmic, and anticonvulsant drugs.
    Ragsdale DS; Scheuer T; Catterall WA
    Mol Pharmacol; 1991 Nov; 40(5):756-65. PubMed ID: 1658608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Block of inactivation-deficient cardiac Na(+) channels by acetyl-KIFMK-amide.
    Wang SY; Wang GK
    Biochem Biophys Res Commun; 2005 Apr; 329(2):780-8. PubMed ID: 15737654
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An improved model for the binding of lidocaine and structurally related local anaesthetics to fast-inactivated voltage-operated sodium channels, showing evidence of cooperativity.
    Leuwer M; Haeseler G; Hecker H; Bufler J; Dengler R; Aronson JK
    Br J Pharmacol; 2004 Jan; 141(1):47-54. PubMed ID: 14662728
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.
    Sheets MF; Hanck DA
    J Physiol; 2007 Jul; 582(Pt 1):317-34. PubMed ID: 17510181
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cardiac sodium channels (hH1) are intrinsically more sensitive to block by lidocaine than are skeletal muscle (mu 1) channels.
    Nuss HB; Tomaselli GF; Marbán E
    J Gen Physiol; 1995 Dec; 106(6):1193-209. PubMed ID: 8786356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.