BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

552 related articles for article (PubMed ID: 15547111)

  • 1. 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
    Schneider-Stock R; Diab-Assef M; Rohrbeck A; Foltzer-Jourdainne C; Boltze C; Hartig R; Schönfeld P; Roessner A; Gali-Muhtasib H
    J Pharmacol Exp Ther; 2005 Feb; 312(2):525-36. PubMed ID: 15547111
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
    Shin DY; Sung Kang H; Kim GY; Kim WJ; Yoo YH; Choi YH
    Biomed Pharmacother; 2013 May; 67(4):305-11. PubMed ID: 23582784
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
    Deng T; Zhang Y
    Life Sci; 2009 Feb; 84(9-10):311-20. PubMed ID: 19159630
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
    Schmelz K; Wagner M; Dörken B; Tamm I
    Int J Cancer; 2005 May; 114(5):683-95. PubMed ID: 15609309
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Effects of p53 inhibitor-alpha on the proliferation and apoptosis in large intestinal epithelial cells damaged by hyperthermic chemotherapy].
    Zhang AP; Liu BH; Zhang LY; Tong WD; He YJ; Fu T; Luo DL
    Zhonghua Yi Xue Za Zhi; 2006 Jan; 86(2):93-7. PubMed ID: 16620711
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.
    Nishioka C; Ikezoe T; Yang J; Komatsu N; Koeffler HP; Yokoyama A
    Int J Cancer; 2009 Sep; 125(5):1168-76. PubMed ID: 19422044
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.
    Pulukuri SM; Rao JS
    Int J Oncol; 2005 Apr; 26(4):863-71. PubMed ID: 15753979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of the DNA methyltranfserases inhibitor 5-Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells.
    Kornicka K; Marycz K; Marędziak M; Tomaszewski KA; Nicpoń J
    J Cell Mol Med; 2017 Feb; 21(2):387-401. PubMed ID: 27998022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells.
    Boyanapalli SS; Li W; Fuentes F; Guo Y; Ramirez CN; Gonzalez XP; Pung D; Kong AN
    Pharmacol Res; 2016 Dec; 114():175-184. PubMed ID: 27818231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
    Liu J; Xie YS; Wang FL; Zhang LJ; Zhang Y; Luo HS
    Biomed Pharmacother; 2013 Feb; 67(1):78-87. PubMed ID: 23201008
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-Aza-2'-deoxycytidine, a DNA methylation inhibitor, induces cytotoxicity, cell cycle dynamics and alters expression of DNA methyltransferase 1 and 3A in mouse hippocampus-derived neuronal HT22 cells.
    Yang J; Tian X; Yang J; Cui J; Jiang S; Shi R; Liu Y; Liu X; Xu W; Xie W; Jia X; Bade R; Zhang T; Zhang M; Gong K; Yan S; Yang Z; Shao G
    J Toxicol Environ Health A; 2017; 80(22):1222-1229. PubMed ID: 28880816
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.
    Zheng QH; Ma LW; Zhu WG; Zhang ZY; Tong TJ
    J Cell Biochem; 2006 Aug; 98(5):1230-48. PubMed ID: 16514663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
    Liu J; Zhang Y; Xie YS; Wang FL; Zhang LJ; Deng T; Luo HS
    Oncol Rep; 2012 Aug; 28(2):545-52. PubMed ID: 22664909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
    Chen W; Gao N; Shen Y; Cen JN
    J Gastroenterol Hepatol; 2010 Apr; 25(4):823-31. PubMed ID: 20492341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.
    Nishioka C; Ikezoe T; Yang J; Udaka K; Yokoyama A
    Leuk Res; 2011 Jul; 35(7):932-9. PubMed ID: 21550660
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent].
    Du HL; Qi Y; Shi YJ; Bu DF; Wu SL
    Ai Zheng; 2002 Oct; 21(10):1057-61. PubMed ID: 12508642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines].
    Chen YX; Fang JY; Lu J; Qiu DK
    Zhonghua Yi Xue Za Zhi; 2004 Feb; 84(4):312-7. PubMed ID: 15059516
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Down-regulation of p16 and MGMT promotes the anti-proliferative and pro-apoptotic effects of 5-Aza-dC and radiation on cervical cancer cells.
    Chen GD; Qian DY; Li ZG; Fan GY; You KL; Wu YL
    Cell Biochem Funct; 2017 Dec; 35(8):488-496. PubMed ID: 29143344
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.
    Crea F; Giovannetti E; Cortesi F; Mey V; Nannizzi S; Gallegos Ruiz MI; Ricciardi S; Del Tacca M; Peters GJ; Danesi R
    Mol Cancer Ther; 2009 Jul; 8(7):1964-73. PubMed ID: 19531575
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
    Ishiguro M; Iida S; Uetake H; Morita S; Makino H; Kato K; Takagi Y; Enomoto M; Sugihara K
    Ann Surg Oncol; 2007 May; 14(5):1752-62. PubMed ID: 17195906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.