149 related articles for article (PubMed ID: 15548515)
21. Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction.
Feng B; Gorin A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
Biochemistry; 1997 Nov; 36(45):13769-79. PubMed ID: 9374853
[TBL] [Abstract][Full Text] [Related]
22. Formation and persistence of benzo[a]pyrene-DNA adducts in mouse epidermis in vivo: importance of adduct conformation.
Suh M; Ariese F; Small GJ; Jankowiak R; Hewer A; Phillips DH
Carcinogenesis; 1995 Oct; 16(10):2561-9. PubMed ID: 7586167
[TBL] [Abstract][Full Text] [Related]
23. Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
Lin CH; Huang X; Kolbanovskii A; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
J Mol Biol; 2001 Mar; 306(5):1059-80. PubMed ID: 11237618
[TBL] [Abstract][Full Text] [Related]
24. Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.
Cosman M; de los Santos C; Fiala R; Hingerty BE; Ibanez V; Luna E; Harvey R; Geacintov NE; Broyde S; Patel DJ
Biochemistry; 1993 Apr; 32(16):4145-55. PubMed ID: 8476845
[TBL] [Abstract][Full Text] [Related]
25. Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations.
Liyanage PS; Walker AR; Brenlla A; Cisneros GA; Romano LJ; Rueda D
Sci Rep; 2017 Dec; 7(1):17383. PubMed ID: 29234107
[TBL] [Abstract][Full Text] [Related]
26. Interactions between DNA polymerase beta and the major covalent adduct of the carcinogen (+)-anti-benzo[a]pyrene diol epoxide with DNA at a primer-template junction.
Singh SB; Beard WA; Hingerty BE; Wilson SH; Broyde S
Biochemistry; 1998 Jan; 37(3):878-84. PubMed ID: 9454577
[TBL] [Abstract][Full Text] [Related]
27. Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase.
Xu P; Oum L; Beese LS; Geacintov NE; Broyde S
Nucleic Acids Res; 2007; 35(13):4275-88. PubMed ID: 17576677
[TBL] [Abstract][Full Text] [Related]
28. Stereochemical origin of opposite orientations in DNA adducts derived from enantiomeric anti-benzo[a]pyrene diol epoxides with different tumorigenic potentials.
Xie XM; Geacintov NE; Broyde S
Biochemistry; 1999 Mar; 38(10):2956-68. PubMed ID: 10074348
[TBL] [Abstract][Full Text] [Related]
29. Monitoring the conformation of benzo[a]pyrene adducts in the polymerase active site using fluorescence resonance energy transfer.
Christian TD; Romano LJ
Biochemistry; 2009 Jun; 48(23):5382-8. PubMed ID: 19435285
[TBL] [Abstract][Full Text] [Related]
30. Molecular dynamics of a food carcinogen-DNA adduct in a replicative DNA polymerase suggest hindered nucleotide incorporation and extension.
Zhang L; Shapiro R; Broyde S
Chem Res Toxicol; 2005 Sep; 18(9):1347-63. PubMed ID: 16167826
[TBL] [Abstract][Full Text] [Related]
31. Lesion bypass of N2-ethylguanine by human DNA polymerase iota.
Pence MG; Blans P; Zink CN; Hollis T; Fishbein JC; Perrino FW
J Biol Chem; 2009 Jan; 284(3):1732-40. PubMed ID: 18984581
[TBL] [Abstract][Full Text] [Related]
32. Quantitative analysis of translesion DNA synthesis across a benzo[a]pyrene-guanine adduct in mammalian cells: the role of DNA polymerase kappa.
Avkin S; Goldsmith M; Velasco-Miguel S; Geacintov N; Friedberg EC; Livneh Z
J Biol Chem; 2004 Dec; 279(51):53298-305. PubMed ID: 15475561
[TBL] [Abstract][Full Text] [Related]
33. Structural and dynamic characterization of polymerase κ's minor groove lesion processing reveals how adduct topology impacts fidelity.
Lior-Hoffmann L; Ding S; Geacintov NE; Zhang Y; Broyde S
Biochemistry; 2014 Sep; 53(35):5683-91. PubMed ID: 25148552
[TBL] [Abstract][Full Text] [Related]
34. Conformational Flexibility of the Benzyl-Guanine Adduct in a Bypass Polymerase Active Site Permits Replication: Insights from Molecular Dynamics Simulations.
Wilson KA; Wetmore SD
Chem Res Toxicol; 2017 Nov; 30(11):2013-2022. PubMed ID: 28810119
[TBL] [Abstract][Full Text] [Related]
35. Effects of solvent on DNA adduct formation in skin and lung of CD1 mice exposed cutaneously to benzo(a)pyrene.
Booth ED; Loose RW; Watson WP
Arch Toxicol; 1999 Aug; 73(6):316-22. PubMed ID: 10447559
[TBL] [Abstract][Full Text] [Related]
36. Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.
Sassa A; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Nohmi T
Mutat Res; 2011 Jan; 718(1-2):10-7. PubMed ID: 21078407
[TBL] [Abstract][Full Text] [Related]
37. Adduct size limits efficient and error-free bypass across bulky N2-guanine DNA lesions by human DNA polymerase eta.
Choi JY; Guengerich FP
J Mol Biol; 2005 Sep; 352(1):72-90. PubMed ID: 16061253
[TBL] [Abstract][Full Text] [Related]
38. Benzo[a]pyrene-dG adduct interference illuminates the interface of vaccinia topoisomerase with the DNA minor groove.
Tian L; Sayer JM; Kroth H; Kalena G; Jerina DM; Shuman S
J Biol Chem; 2003 Mar; 278(11):9905-11. PubMed ID: 12524450
[TBL] [Abstract][Full Text] [Related]
39. Altering DNA polymerase incorporation fidelity by distorting the dNTP binding pocket with a bulky carcinogen-damaged template.
Yan SF; Wu M; Geacintov NE; Broyde S
Biochemistry; 2004 Jun; 43(24):7750-65. PubMed ID: 15196018
[TBL] [Abstract][Full Text] [Related]
40. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.
Alexandrov K; Rojas M; Geneste O; Castegnaro M; Camus AM; Petruzzelli S; Giuntini C; Bartsch H
Cancer Res; 1992 Nov; 52(22):6248-53. PubMed ID: 1423269
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]