138 related articles for article (PubMed ID: 15548998)
1. T cell acute lymphoblastic leukemia/lymphoma: a human cancer commonly associated with aberrant NOTCH1 signaling.
Pear WS; Aster JC
Curr Opin Hematol; 2004 Nov; 11(6):426-33. PubMed ID: 15548998
[TBL] [Abstract][Full Text] [Related]
2. OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.
Lin YW; Deveney R; Barbara M; Iscove NN; Nimer SD; Slape C; Aplan PD
Cancer Res; 2005 Aug; 65(16):7151-8. PubMed ID: 16103065
[TBL] [Abstract][Full Text] [Related]
3. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Weng AP; Millholland JM; Yashiro-Ohtani Y; Arcangeli ML; Lau A; Wai C; Del Bianco C; Rodriguez CG; Sai H; Tobias J; Li Y; Wolfe MS; Shachaf C; Felsher D; Blacklow SC; Pear WS; Aster JC
Genes Dev; 2006 Aug; 20(15):2096-109. PubMed ID: 16847353
[TBL] [Abstract][Full Text] [Related]
4. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia.
Marchesini M; Gherli A; Montanaro A; Patrizi L; Sorrentino C; Pagliaro L; Rompietti C; Kitara S; Heit S; Olesen CE; Møller JV; Savi M; Bocchi L; Vilella R; Rizzi F; Baglione M; Rastelli G; Loiacono C; La Starza R; Mecucci C; Stegmaier K; Aversa F; Stilli D; Lund Winther AM; Sportoletti P; Bublitz M; Dalby-Brown W; Roti G
Cell Chem Biol; 2020 Jun; 27(6):678-697.e13. PubMed ID: 32386594
[TBL] [Abstract][Full Text] [Related]
5. An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia.
Knoechel B; Roderick JE; Williamson KE; Zhu J; Lohr JG; Cotton MJ; Gillespie SM; Fernandez D; Ku M; Wang H; Piccioni F; Silver SJ; Jain M; Pearson D; Kluk MJ; Ott CJ; Shultz LD; Brehm MA; Greiner DL; Gutierrez A; Stegmaier K; Kung AL; Root DE; Bradner JE; Aster JC; Kelliher MA; Bernstein BE
Nat Genet; 2014 Apr; 46(4):364-70. PubMed ID: 24584072
[TBL] [Abstract][Full Text] [Related]
6. Augmented efficacy with the combination of blockade of the Notch-1 pathway, bortezomib and romidepsin in a murine MT-1 adult T-cell leukemia model.
Yu P; Petrus MN; Ju W; Zhang M; Conlon KC; Nakagawa M; Maeda M; Bamford RN; Waldmann TA
Leukemia; 2015 Mar; 29(3):556-66. PubMed ID: 25118879
[TBL] [Abstract][Full Text] [Related]
7. CAD204520 Targets
Pagliaro L; Cerretani E; Vento F; Montanaro A; Moron Dalla Tor L; Simoncini E; Giaimo M; Gherli A; Zamponi R; Tartaglione I; Lorusso B; Scita M; Russo F; Sammarelli G; Todaro G; Silini EM; Rigolin GM; Quaini F; Cuneo A; Roti G
Int J Mol Sci; 2024 Jan; 25(2):. PubMed ID: 38255842
[No Abstract] [Full Text] [Related]
8. The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.
Pinnell N; Yan R; Cho HJ; Keeley T; Murai MJ; Liu Y; Alarcon AS; Qin J; Wang Q; Kuick R; Elenitoba-Johnson KS; Maillard I; Samuelson LC; Cierpicki T; Chiang MY
Immunity; 2015 Nov; 43(5):870-83. PubMed ID: 26522984
[TBL] [Abstract][Full Text] [Related]
9. A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Carofino BL; Ayanga B; Justice MJ
Dis Model Mech; 2013 Nov; 6(6):1494-506. PubMed ID: 24046360
[TBL] [Abstract][Full Text] [Related]
10. NOTCH1-Induced T-Cell Acute Lymphoblastic Leukemia In Vivo Models.
Campagnari A; Belver L
Methods Mol Biol; 2024; 2773():9-24. PubMed ID: 38236532
[TBL] [Abstract][Full Text] [Related]
11. NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.
Giambra V; Jenkins CR; Wang H; Lam SH; Shevchuk OO; Nemirovsky O; Wai C; Gusscott S; Chiang MY; Aster JC; Humphries RK; Eaves C; Weng AP
Nat Med; 2012 Nov; 18(11):1693-8. PubMed ID: 23086478
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.
Baran N; Lodi A; Dhungana Y; Herbrich S; Collins M; Sweeney S; Pandey R; Skwarska A; Patel S; Tremblay M; Kuruvilla VM; Cavazos A; Kaplan M; Warmoes MO; Veiga DT; Furudate K; Rojas-Sutterin S; Haman A; Gareau Y; Marinier A; Ma H; Harutyunyan K; Daher M; Garcia LM; Al-Atrash G; Piya S; Ruvolo V; Yang W; Shanmugavelandy SS; Feng N; Gay J; Du D; Yang JJ; Hoff FW; Kaminski M; Tomczak K; Eric Davis R; Herranz D; Ferrando A; Jabbour EJ; Emilia Di Francesco M; Teachey DT; Horton TM; Kornblau S; Rezvani K; Sauvageau G; Gagea M; Andreeff M; Takahashi K; Marszalek JR; Lorenzi PL; Yu J; Tiziani S; Hoang T; Konopleva M
Nat Commun; 2022 May; 13(1):2801. PubMed ID: 35589701
[TBL] [Abstract][Full Text] [Related]
13. Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress.
Melnick AF; Mullin C; Lin K; McCarter AC; Liang S; Liu YE; Wang Q; Jerome NA; Choe E; Kunnath N; Bodanapu G; Akter F; Magnuson B; Kumar S; Lombard DB; Muntean AG; Ljungman M; Sekiguchi J; Ryan RJH; Chiang MY
Blood; 2023 Dec; 142(25):2159-2174. PubMed ID: 37616559
[TBL] [Abstract][Full Text] [Related]
14. Can one target T-cell ALL?
Ferrando A
Best Pract Res Clin Haematol; 2018 Dec; 31(4):361-366. PubMed ID: 30466748
[TBL] [Abstract][Full Text] [Related]
15. Gamma-delta T-cell acute lymphoblastic lymphoma/leukemia: a report of a rare entity.
George GV; Kajstura M; Evans AG; Syposs CR
J Hematop; 2024 Mar; ():. PubMed ID: 38528212
[TBL] [Abstract][Full Text] [Related]
16. The genetics and molecular biology of T-ALL.
Girardi T; Vicente C; Cools J; De Keersmaecker K
Blood; 2017 Mar; 129(9):1113-1123. PubMed ID: 28115373
[TBL] [Abstract][Full Text] [Related]
17. Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia.
Xu J; Peng J; Sun S; Wang D; Yuan W; Yang X; Shi T; Wang R; Liu H; Zhang P; Zhu HH
Br J Haematol; 2024 Apr; ():. PubMed ID: 38685813
[TBL] [Abstract][Full Text] [Related]
18. Quadruple and Truncated MEK3 Mutants Identified from Acute Lymphoblastic Leukemia Promote Degradation and Enhance Proliferation.
Ayala-Marin YM; Grant AH; Rodriguez G; Kirken RA
Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830095
[TBL] [Abstract][Full Text] [Related]
19. Pharmacodynamic and Toxicity Studies of 6-Isopropyldithio-2'-guanosine Analogs in Acute T-Lymphoblastic Leukemia.
Song T; Yu Z; Shen Q; Xu Y; Hu H; Liu J; Zeng K; Lei J; Yu L
Cancers (Basel); 2024 Apr; 16(9):. PubMed ID: 38730567
[TBL] [Abstract][Full Text] [Related]
20. Near-early T-cell precursor acute lymphoblastic leukemia following a diagnosis of essential thrombocythemia.
Lebecque B; Tassin T
EJHaem; 2024 Feb; 5(1):276-277. PubMed ID: 38406523
[No Abstract] [Full Text] [Related]
[Next] [New Search]
