BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 15550400)

  • 1. Cyclooxygenase-2 suppresses hypoxia-induced apoptosis via a combination of direct and indirect inhibition of p53 activity in a human prostate cancer cell line.
    Liu XH; Kirschenbaum A; Yu K; Yao S; Levine AC
    J Biol Chem; 2005 Feb; 280(5):3817-23. PubMed ID: 15550400
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of p53 signalling in acetylsalicylic acid-induced apoptosis in OC2 human oral cancer cells.
    Ho CC; Yang XW; Lee TL; Liao PH; Yang SH; Tsai CH; Chou MY
    Eur J Clin Invest; 2003 Oct; 33(10):875-82. PubMed ID: 14511359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.
    Lee SJ; Lim CJ; Min JK; Lee JK; Kim YM; Lee JY; Won MH; Kwon YG
    Cell Death Differ; 2007 Jun; 14(6):1106-16. PubMed ID: 17318220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of COX-2 protein expression by Akt in endometrial cancer cells is mediated through NF-kappaB/IkappaB pathway.
    St-Germain ME; Gagnon V; Parent S; Asselin E
    Mol Cancer; 2004 Mar; 3():7. PubMed ID: 15016316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxic regulation of angiopoietin-2 expression in endothelial cells.
    Pichiule P; Chavez JC; LaManna JC
    J Biol Chem; 2004 Mar; 279(13):12171-80. PubMed ID: 14702352
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.
    Koumenis C; Alarcon R; Hammond E; Sutphin P; Hoffman W; Murphy M; Derr J; Taya Y; Lowe SW; Kastan M; Giaccia A
    Mol Cell Biol; 2001 Feb; 21(4):1297-310. PubMed ID: 11158315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.
    Xia M; Knezevic D; Tovar C; Huang B; Heimbrook DC; Vassilev LT
    Cell Cycle; 2008 Jun; 7(11):1604-12. PubMed ID: 18520179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons.
    Zhu Y; Mao XO; Sun Y; Xia Z; Greenberg DA
    J Biol Chem; 2002 Jun; 277(25):22909-14. PubMed ID: 11948180
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S; Gupta S
    Clin Cancer Res; 2004 May; 10(9):3169-78. PubMed ID: 15131058
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mdm2 ligase dead mutants did not act in a dominant negative manner to re-activate p53, but promoted tumor cell growth.
    Swaroop M; Sun Y
    Anticancer Res; 2003; 23(4):3167-74. PubMed ID: 12926050
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms.
    Zhong H; Willard M; Simons J
    Int J Cancer; 2004 Nov; 112(4):585-95. PubMed ID: 15382039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified.
    Mayo LD; Seo YR; Jackson MW; Smith ML; Rivera Guzman J; Korgaonkar CK; Donner DB
    J Biol Chem; 2005 Jul; 280(28):25953-9. PubMed ID: 15843377
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
    Kitagawa M; Aonuma M; Lee SH; Fukutake S; McCormick F
    Oncogene; 2008 Sep; 27(40):5303-14. PubMed ID: 18521084
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upregulation of vascular endothelial growth factor by cobalt chloride-simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line.
    Liu XH; Kirschenbaum A; Yao S; Stearns ME; Holland JF; Claffey K; Levine AC
    Clin Exp Metastasis; 1999; 17(8):687-94. PubMed ID: 10919714
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of p53 or p27 overexpression on cyclooxygenase-2 gene expression in head and neck squamous cell carcinoma cell lines.
    Lee DW; Park SW; Park SY; Heo DS; Kim KH; Sung MW
    Head Neck; 2004 Aug; 26(8):706-15. PubMed ID: 15287038
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia induces high-mobility-group protein I(Y) and transcription of the cyclooxygenase-2 gene in human vascular endothelium.
    Ji YS; Xu Q; Schmedtje JF
    Circ Res; 1998 Aug; 83(3):295-304. PubMed ID: 9710122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma.
    Huang SP; Wu MS; Shun CT; Wang HP; Hsieh CY; Kuo ML; Lin JT
    J Biomed Sci; 2005; 12(1):229-41. PubMed ID: 15864753
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of cyclooxygenase (COX)-2 expression by Tet-inducible COX-2 antisense cDNA in hormone-refractory prostate cancer significantly slows tumor growth and improves efficacy of chemotherapeutic drugs.
    Dandekar DS; Lokeshwar BL
    Clin Cancer Res; 2004 Dec; 10(23):8037-47. PubMed ID: 15585639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia.
    Suzuki H; Tomida A; Tsuruo T
    Oncogene; 2001 Sep; 20(41):5779-88. PubMed ID: 11593383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.