BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 15553925)

  • 1. Structural bioinformatics and QSAR analysis applied to the acetylcholinesterase and bispyridinium aldoximes.
    Mager PP; Weber A
    Drug Des Discov; 2003; 18(4):127-50. PubMed ID: 15553925
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.
    Mercey G; Verdelet T; Renou J; Kliachyna M; Baati R; Nachon F; Jean L; Renard PY
    Acc Chem Res; 2012 May; 45(5):756-66. PubMed ID: 22360473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico pharmacophore model for tabun-inhibited acetylcholinesterase reactivators: a study of their stereoelectronic properties.
    Bhattacharjee AK; Kuca K; Musilek K; Gordon RK
    Chem Res Toxicol; 2010 Jan; 23(1):26-36. PubMed ID: 20028185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antidotal efficacy of pyridinium chloride derivatives against soman poisoning.
    Vrdoljak AL; Lovrić J; Radić B; Zlender V
    Basic Clin Pharmacol Toxicol; 2006 Jul; 99(1):17-21. PubMed ID: 16867165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluorinated pyridinium oximes as potential reactivators for acetylcholinesterases inhibited by paraoxon organophosphorus agent.
    Jeong HC; Park NJ; Chae CH; Musilek K; Kassa J; Kuca K; Jung YS
    Bioorg Med Chem; 2009 Sep; 17(17):6213-7. PubMed ID: 19665386
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice.
    Kassa J; Karasova J; Musilek K; Kuca K
    Toxicology; 2008 Jan; 243(3):311-6. PubMed ID: 18054821
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel nerve-agent antidote design based on crystallographic and mass spectrometric analyses of tabun-conjugated acetylcholinesterase in complex with antidotes.
    Ekström FJ; Astot C; Pang YP
    Clin Pharmacol Ther; 2007 Sep; 82(3):282-93. PubMed ID: 17443135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates.
    Ekström F; Pang YP; Boman M; Artursson E; Akfur C; Börjegren S
    Biochem Pharmacol; 2006 Aug; 72(5):597-607. PubMed ID: 16876764
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of monoquaternary pyridinium oximes potency to reactivate tabun-inhibited human acetylcholinesterase.
    Odzak R; Calić M; Hrenar T; Primozic I; Kovarik Z
    Toxicology; 2007 Apr; 233(1-3):85-96. PubMed ID: 16962227
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New oxime reactivators connected with CH2O(CH2)nOCH2 linker and their reactivation potency for organophosphorus agents-inhibited acetylcholinesterase.
    Yang GY; Oh KA; Park NJ; Jung YS
    Bioorg Med Chem; 2007 Dec; 15(24):7704-10. PubMed ID: 17869525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Why acetylcholinesterase reactivators do not work in butyrylcholinesterase.
    Wiesner J; Kríz Z; Kuca K; Jun D; Koca J
    J Enzyme Inhib Med Chem; 2010 Jun; 25(3):318-22. PubMed ID: 19874115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ligand-based 3D QSAR analysis of reactivation potency of mono- and bis-pyridinium aldoximes toward VX-inhibited rat acetylcholinesterase.
    Dolezal R; Korabecny J; Malinak D; Honegr J; Musilek K; Kuca K
    J Mol Graph Model; 2015 Mar; 56():113-29. PubMed ID: 25588616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An evaluation of reactivating and therapeutic efficacy of newly developed oximes (K206, K269) and commonly used oximes (obidoxime, HI-6) in cyclosarin-poisoned rats and mice.
    Kassa J; Karasova J; Musilek K; Kuca K; Bajgar J
    Clin Toxicol (Phila); 2009 Jan; 47(1):72-6. PubMed ID: 18686075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.
    Musilek K; Holas O; Kuca K; Jun D; Dohnal V; Opletalova V; Dolezal M
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3172-6. PubMed ID: 17383875
    [TBL] [Abstract][Full Text] [Related]  

  • 15. QSAR models for the reactivation of sarin inhibited acetylcholinesterase by quaternary pyridinium oximes based on Monte Carlo method.
    Veselinović AM; Veselinović JB; Toropov AA; Toropova AP; Nikolić GM
    Curr Comput Aided Drug Des; 2014; 10(3):266-73. PubMed ID: 25756672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
    Carletti E; Aurbek N; Gillon E; Loiodice M; Nicolet Y; Fontecilla-Camps JC; Masson P; Thiermann H; Nachon F; Worek F
    Biochem J; 2009 Jun; 421(1):97-106. PubMed ID: 19368529
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel acetylcholinesterase reactivator K112 and its cholinergic properties.
    Soukup O; Kristofikova Z; Proska J; Tobin G; Patocka J; Marek J; Jun D; Fusek J; Ripova D; Kuca K
    Biomed Pharmacother; 2010 Oct; 64(8):541-5. PubMed ID: 20634031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
    Aurbek N; Thiermann H; Eyer F; Eyer P; Worek F
    Toxicology; 2009 May; 259(3):133-9. PubMed ID: 19428953
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of quantitative structure activity relationships for the binding affinity of methoxypyridinium cations for human acetylcholinesterase.
    Morrill JA; Topczewski JJ; Lodge AM; Yasapala N; Quinn DM
    J Mol Graph Model; 2015 Nov; 62():181-189. PubMed ID: 26454505
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.
    Musilek K; Kuca K; Jun D; Dohnal V; Dolezal M
    Bioorg Med Chem Lett; 2006 Feb; 16(3):622-7. PubMed ID: 16288867
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.