BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 15561098)

  • 1. Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway.
    Agner J; Falck J; Lukas J; Bartek J
    Exp Cell Res; 2005 Jan; 302(2):162-9. PubMed ID: 15561098
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.
    Xiao Z; Chen Z; Gunasekera AH; Sowin TJ; Rosenberg SH; Fesik S; Zhang H
    J Biol Chem; 2003 Jun; 278(24):21767-73. PubMed ID: 12676925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J; Ang XL; Ye X; Livingstone M; Harper JW
    J Biol Chem; 2008 Jul; 283(28):19322-8. PubMed ID: 18480045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells.
    Koledova Z; Kafkova LR; Krämer A; Divoky V
    Stem Cells; 2010 Mar; 28(3):450-61. PubMed ID: 20104581
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J; Mailand N; Syljuåsen RG; Bartek J; Lukas J
    Nature; 2001 Apr; 410(6830):842-7. PubMed ID: 11298456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.
    Hassepass I; Voit R; Hoffmann I
    J Biol Chem; 2003 Aug; 278(32):29824-9. PubMed ID: 12759351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
    Xiao Z; Xue J; Sowin TJ; Zhang H
    Mol Cancer Ther; 2006 Aug; 5(8):1935-43. PubMed ID: 16928813
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
    Jin J; Shirogane T; Xu L; Nalepa G; Qin J; Elledge SJ; Harper JW
    Genes Dev; 2003 Dec; 17(24):3062-74. PubMed ID: 14681206
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
    Yin MB; Li ZR; Cao S; Durrani FA; Azrak RG; Frank C; Rustum YM
    Mol Pharmacol; 2004 Jul; 66(1):153-60. PubMed ID: 15213307
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin.
    Zhang Y; Qu D; Morris EJ; O'Hare MJ; Callaghan SM; Slack RS; Geller HM; Park DS
    J Neurosci; 2006 Aug; 26(34):8819-28. PubMed ID: 16928871
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine.
    Sampath D; Shi Z; Plunkett W
    Mol Pharmacol; 2002 Sep; 62(3):680-8. PubMed ID: 12181445
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma.
    Wang XQ; Zhu YQ; Lui KS; Cai Q; Lu P; Poon RT
    Clin Cancer Res; 2008 Nov; 14(21):6813-20. PubMed ID: 18980975
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Degradation of Cdc25A phosphatase in HeLa cells under normal and stress conditions].
    Goloudina AR; Aksenov ND; Pospelov VA
    Tsitologiia; 2004; 46(5):423-30. PubMed ID: 15344887
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.
    Zhao H; Watkins JL; Piwnica-Worms H
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14795-800. PubMed ID: 12399544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rapid destruction of human Cdc25A in response to DNA damage.
    Mailand N; Falck J; Lukas C; Syljuâsen RG; Welcker M; Bartek J; Lukas J
    Science; 2000 May; 288(5470):1425-9. PubMed ID: 10827953
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
    Sørensen CS; Syljuåsen RG; Falck J; Schroeder T; Rönnstrand L; Khanna KK; Zhou BB; Bartek J; Lukas J
    Cancer Cell; 2003 Mar; 3(3):247-58. PubMed ID: 12676583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The regulatory beta-subunit of protein kinase CK2 accelerates the degradation of CDC25A phosphatase through the checkpoint kinase Chk1.
    Kreutzer J; Guerra B
    Int J Oncol; 2007 Nov; 31(5):1251-9. PubMed ID: 17912454
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells.
    Sandhu C; Donovan J; Bhattacharya N; Stampfer M; Worland P; Slingerland J
    Oncogene; 2000 Nov; 19(47):5314-23. PubMed ID: 11103932
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism.
    Uto K; Inoue D; Shimuta K; Nakajo N; Sagata N
    EMBO J; 2004 Aug; 23(16):3386-96. PubMed ID: 15272308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Human embryonic stem cells are capable of executing G1/S checkpoint activation.
    Bárta T; Vinarský V; Holubcová Z; Dolezalová D; Verner J; Pospísilová S; Dvorák P; Hampl A
    Stem Cells; 2010 Jul; 28(7):1143-52. PubMed ID: 20518019
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.