BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 15562828)

  • 1. Structural biology of insulin and IGF-1 receptors.
    De Meyts P; Palsgaard J; Sajid W; Theede AM; Aladdin H
    Novartis Found Symp; 2004; 262():160-71; discussion 171-6, 265-8. PubMed ID: 15562828
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Growth factor receptors: structure, mechanism, and drug discovery.
    McInnes C; Sykes BD
    Biopolymers; 1997; 43(5):339-66. PubMed ID: 9566117
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C; Lawrence M; Streltsov V; Garrett T; McKern N; Lou MZ; Lovrecz G; Adams T
    Acta Physiol (Oxf); 2008 Jan; 192(1):3-9. PubMed ID: 18171424
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
    Whitten AE; Smith BJ; Menting JG; Margetts MB; McKern NM; Lovrecz GO; Adams TE; Richards K; Bentley JD; Trewhella J; Ward CW; Lawrence MC
    J Mol Biol; 2009 Dec; 394(5):878-92. PubMed ID: 19835884
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin receptor structure and its implications for the IGF-1 receptor.
    Lawrence MC; McKern NM; Ward CW
    Curr Opin Struct Biol; 2007 Dec; 17(6):699-705. PubMed ID: 17851071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The insulin receptor: a prototype for dimeric, allosteric membrane receptors?
    De Meyts P
    Trends Biochem Sci; 2008 Aug; 33(8):376-84. PubMed ID: 18640841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural relationships between the insulin receptor and epidermal growth factor receptor families and other proteins.
    Ward CW; Garrett TP
    Curr Opin Drug Discov Devel; 2004 Sep; 7(5):630-8. PubMed ID: 15503865
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of allosteric ligand-receptor interactions in the insulin/relaxin peptide family: implications for other receptor tyrosine kinases and G-protein-coupled receptors.
    De Meyts P; Gauguin L; Svendsen AM; Sarhan M; Knudsen L; Nøhr J; Kiselyov VV
    Ann N Y Acad Sci; 2009 Apr; 1160():45-53. PubMed ID: 19416158
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [The internal symmetry of the primary structure of the beta-subunits of the tyrosine kinase receptors in insulin superfamily peptides and its relation to their functional activity].
    Shpakov AO
    Tsitologiia; 1997; 39(7):590-600. PubMed ID: 9490500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure and function of VEGF receptors.
    Stuttfeld E; Ballmer-Hofer K
    IUBMB Life; 2009 Sep; 61(9):915-22. PubMed ID: 19658168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of a second ligand binding site of the insulin receptor.
    Hao C; Whittaker L; Whittaker J
    Biochem Biophys Res Commun; 2006 Aug; 347(1):334-9. PubMed ID: 16814253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor.
    Wood ER; Shewchuk L; Hassel A; Nichols J; Truesdale AT; Smith D; Carter HL; Weaver K; Barrett G; Leesnitzer T; Alvarez E; Bardera AI; Alamillo A; Cantizani J; Martin J; Smith GK; Jensen DE; Xie H; Mook R; Kumar R; Kuntz K
    Biochem Pharmacol; 2009 Dec; 78(12):1438-47. PubMed ID: 19665448
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.
    Zaccheo OJ; Prince SN; Miller DM; Williams C; Kemp CF; Brown J; Jones EY; Catto LE; Crump MP; Hassan AB
    J Mol Biol; 2006 Jun; 359(2):403-21. PubMed ID: 16631789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells.
    Johansson GS; Arnqvist HJ
    Am J Physiol Endocrinol Metab; 2006 Nov; 291(5):E1124-30. PubMed ID: 16803852
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A; Carroll JM; Brierley GV; Cosgrove L; Wallace J; Forbes B; Roberts CT
    Mol Cell Biol; 2007 May; 27(10):3569-77. PubMed ID: 17325037
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the insulin receptor ectodomain reveals a folded-over conformation.
    McKern NM; Lawrence MC; Streltsov VA; Lou MZ; Adams TE; Lovrecz GO; Elleman TC; Richards KM; Bentley JD; Pilling PA; Hoyne PA; Cartledge KA; Pham TM; Lewis JL; Sankovich SE; Stoichevska V; Da Silva E; Robinson CP; Frenkel MJ; Sparrow LG; Fernley RT; Epa VC; Ward CW
    Nature; 2006 Sep; 443(7108):218-21. PubMed ID: 16957736
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG; Ward CW; Margetts MB; Lawrence MC
    Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.
    Glendorf T; Sørensen AR; Nishimura E; Pettersson I; Kjeldsen T
    Biochemistry; 2008 Apr; 47(16):4743-51. PubMed ID: 18376848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structural biology of growth factor receptor activation.
    Harmer NJ; Chirgadze D; Hyun Kim K; Pellegrini L; Blundell TL
    Biophys Chem; 2003; 100(1-3):545-53. PubMed ID: 12646390
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterisation of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells.
    Chisalita SI; Nitert MD; Arnqvist HJ
    Growth Horm IGF Res; 2006 Aug; 16(4):258-66. PubMed ID: 16914341
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.