BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 15566282)

  • 1. Arylthioindoles, potent inhibitors of tubulin polymerization.
    De Martino G; La Regina G; Coluccia A; Edler MC; Barbera MC; Brancale A; Wilcox E; Hamel E; Artico M; Silvestri R
    J Med Chem; 2004 Dec; 47(25):6120-3. PubMed ID: 15566282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
    De Martino G; Edler MC; La Regina G; Coluccia A; Barbera MC; Barrow D; Nicholson RI; Chiosis G; Brancale A; Hamel E; Artico M; Silvestri R
    J Med Chem; 2006 Feb; 49(3):947-54. PubMed ID: 16451061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
    J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
    Gastpar R; Goldbrunner M; Marko D; von Angerer E
    J Med Chem; 1998 Dec; 41(25):4965-72. PubMed ID: 9836614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents.
    Liou JP; Chang YL; Kuo FM; Chang CW; Tseng HY; Wang CC; Yang YN; Chang JY; Lee SJ; Hsieh HP
    J Med Chem; 2004 Aug; 47(17):4247-57. PubMed ID: 15293996
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
    La Regina G; Edler MC; Brancale A; Kandil S; Coluccia A; Piscitelli F; Hamel E; De Martino G; Matesanz R; Díaz JF; Scovassi AI; Prosperi E; Lavecchia A; Novellino E; Artico M; Silvestri R
    J Med Chem; 2007 Jun; 50(12):2865-74. PubMed ID: 17497841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Nov; 49(23):6656-9. PubMed ID: 17154496
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
    J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
    Romagnoli R; Baraldi PG; Sarkar T; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Hsieh HP; Hamel E
    J Med Chem; 2008 Mar; 51(5):1464-8. PubMed ID: 18260616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY; Chen YC; Kuo CC; Hsieh HP; Chang CY; Wu JS; Wu SY; Liou JP; Chang JY
    J Med Chem; 2010 Mar; 53(5):2309-13. PubMed ID: 20148562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of tubulin polymerization by 5,6-dihydroindolo[2,1-alpha]isoquinoline derivatives.
    Goldbrunner M; Loidl G; Polossek T; Mannschreck A; von Angerer E
    J Med Chem; 1997 Oct; 40(22):3524-33. PubMed ID: 9357519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H; Ishii Y; Hirano T; Stoiber T; Camacho Gomez JA; Schmidt P; Düssmann H; Burger AM; Prehn JH; Günther EG; Unger E; Umezawa K
    J Med Chem; 2003 Jul; 46(15):3382-94. PubMed ID: 12852768
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
    J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
    Coluccia A; Sabbadin D; Brancale A
    Eur J Med Chem; 2011 Aug; 46(8):3519-25. PubMed ID: 21621885
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F; Zhao H; Li D; Chen H; Quan H; Shi X; Lou L; Hu Y
    J Med Chem; 2011 May; 54(9):3200-5. PubMed ID: 21480626
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of 1-(4'-Indolyl and 6'-Quinolinyl) indoles as a new class of potent anticancer agents.
    Lai MJ; Chang JY; Lee HY; Kuo CC; Lin MH; Hsieh HP; Chang CY; Wu JS; Wu SY; Shey KS; Liou JP
    Eur J Med Chem; 2011 Sep; 46(9):3623-9. PubMed ID: 21641700
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors.
    Beckers T; Reissmann T; Schmidt M; Burger AM; Fiebig HH; Vanhoefer U; Pongratz H; Hufsky H; Hockemeyer J; Frieser M; Mahboobi S
    Cancer Res; 2002 Jun; 62(11):3113-9. PubMed ID: 12036922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
    Edsall AB; Mohanakrishnan AK; Yang D; Fanwick PE; Hamel E; Hanson AD; Agoston GE; Cushman M
    J Med Chem; 2004 Oct; 47(21):5126-39. PubMed ID: 15456256
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.
    Keller L; Beaumont S; Liu JM; Thoret S; Bignon JS; Wdzieczak-Bakala J; Dauban P; Dodd RH
    J Med Chem; 2008 Jun; 51(12):3414-21. PubMed ID: 18503262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.