367 related articles for article (PubMed ID: 15566300)
1. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
Kemnitzer W; Drewe J; Jiang S; Zhang H; Wang Y; Zhao J; Jia S; Herich J; Labreque D; Storer R; Meerovitch K; Bouffard D; Rej R; Denis R; Blais C; Lamothe S; Attardo G; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
J Med Chem; 2004 Dec; 47(25):6299-310. PubMed ID: 15566300
[TBL] [Abstract][Full Text] [Related]
2. Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay.
Cai SX; Nguyen B; Jia S; Herich J; Guastella J; Reddy S; Tseng B; Drewe J; Kasibhatla S
J Med Chem; 2003 Jun; 46(12):2474-81. PubMed ID: 12773051
[TBL] [Abstract][Full Text] [Related]
3. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 4. Structure-activity relationships of N-alkyl substituted pyrrole fused at the 7,8-positions.
Kemnitzer W; Drewe J; Jiang S; Zhang H; Crogan-Grundy C; Labreque D; Bubenick M; Attardo G; Denis R; Lamothe S; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
J Med Chem; 2008 Feb; 51(3):417-23. PubMed ID: 18197614
[TBL] [Abstract][Full Text] [Related]
4. Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay.
Kemnitzer W; Jiang S; Zhang H; Kasibhatla S; Crogan-Grundy C; Blais C; Attardo G; Denis R; Lamothe S; Gourdeau H; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2008 Oct; 18(20):5571-5. PubMed ID: 18805007
[TBL] [Abstract][Full Text] [Related]
5. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions.
Kemnitzer W; Kasibhatla S; Jiang S; Zhang H; Zhao J; Jia S; Xu L; Crogan-Grundy C; Denis R; Barriault N; Vaillancourt L; Charron S; Dodd J; Attardo G; Labrecque D; Lamothe S; Gourdeau H; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2005 Nov; 15(21):4745-51. PubMed ID: 16143530
[TBL] [Abstract][Full Text] [Related]
6. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions.
Kemnitzer W; Jiang S; Wang Y; Kasibhatla S; Crogan-Grundy C; Bubenik M; Labrecque D; Denis R; Lamothe S; Attardo G; Gourdeau H; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2008 Jan; 18(2):603-7. PubMed ID: 18077161
[TBL] [Abstract][Full Text] [Related]
7. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.
Sirisoma N; Kasibhatla S; Nguyen B; Pervin A; Wang Y; Claassen G; Tseng B; Drewe J; Cai SX
Bioorg Med Chem; 2006 Dec; 14(23):7761-73. PubMed ID: 16919962
[TBL] [Abstract][Full Text] [Related]
8. Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay.
Drewe J; Kasibhatla S; Tseng B; Shelton E; Sperandio D; Yee RM; Litvak J; Sendzik M; Spencer JR; Cai SX
Bioorg Med Chem Lett; 2007 Sep; 17(17):4987-90. PubMed ID: 17562361
[TBL] [Abstract][Full Text] [Related]
9. Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the carboxamide group.
Kemnitzer W; Sirisoma N; Nguyen B; Jiang S; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2009 Jun; 19(11):3045-9. PubMed ID: 19394823
[TBL] [Abstract][Full Text] [Related]
10. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1- and 3-positions.
Kemnitzer W; Kuemmerle J; Jiang S; Zhang HZ; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2008 Dec; 18(23):6259-64. PubMed ID: 18952423
[TBL] [Abstract][Full Text] [Related]
11. Discovery of 4-aryl-4H-chromenes as potent apoptosis inducers using a cell- and caspase-based Anti-cancer Screening Apoptosis Program (ASAP): SAR studies and the identification of novel vascular disrupting agents.
Cai SX; Drewe J; Kemnitzer W
Anticancer Agents Med Chem; 2009 May; 9(4):437-56. PubMed ID: 19442043
[TBL] [Abstract][Full Text] [Related]
12. Discovery and SAR of indole-2-carboxylic acid benzylidene-hydrazides as a new series of potent apoptosis inducers using a cell-based HTS assay.
Zhang HZ; Drewe J; Tseng B; Kasibhatla S; Cai SX
Bioorg Med Chem; 2004 Jul; 12(13):3649-55. PubMed ID: 15186849
[TBL] [Abstract][Full Text] [Related]
13. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions.
Kemnitzer W; Kuemmerle J; Jiang S; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2009 Jul; 19(13):3481-4. PubMed ID: 19467598
[TBL] [Abstract][Full Text] [Related]
14. Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure-activity relationships of the 2-aryl group.
Sirisoma N; Pervin A; Nguyen B; Crogan-Grundy C; Kasibhatla S; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2009 Apr; 19(8):2305-9. PubMed ID: 19285392
[TBL] [Abstract][Full Text] [Related]
15. Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay.
Jiang S; Crogan-Grundy C; Drewe J; Tseng B; Cai SX
Bioorg Med Chem Lett; 2008 Nov; 18(21):5725-8. PubMed ID: 18849165
[TBL] [Abstract][Full Text] [Related]
16. Discovery and structure-activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers.
Zhang HZ; Crogan-Grundy C; May C; Drewe J; Tseng B; Cai SX
Bioorg Med Chem; 2009 Apr; 17(7):2852-8. PubMed ID: 19282188
[TBL] [Abstract][Full Text] [Related]
17. Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers.
Kemnitzer W; Sirisoma N; May C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem Lett; 2009 Jul; 19(13):3536-40. PubMed ID: 19464890
[TBL] [Abstract][Full Text] [Related]
18. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 3. Structure-activity relationships of fused rings at the 7,8-positions.
Kemnitzer W; Drewe J; Jiang S; Zhang H; Zhao J; Crogan-Grundy C; Xu L; Lamothe S; Gourdeau H; Denis R; Tseng B; Kasibhatla S; Cai SX
J Med Chem; 2007 Jun; 50(12):2858-64. PubMed ID: 17497765
[TBL] [Abstract][Full Text] [Related]
19. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Prinz H; Ishii Y; Hirano T; Stoiber T; Camacho Gomez JA; Schmidt P; Düssmann H; Burger AM; Prehn JH; Günther EG; Unger E; Umezawa K
J Med Chem; 2003 Jul; 46(15):3382-94. PubMed ID: 12852768
[TBL] [Abstract][Full Text] [Related]
20. Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers.
Zhang HZ; Claassen G; Crogran-Grundy C; Tseng B; Drewe J; Cai SX
Bioorg Med Chem; 2008 Jan; 16(1):222-31. PubMed ID: 17950608
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]