BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 15572581)

  • 1. Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American.
    Kaniwa N; Kurose K; Jinno H; Tanaka-Kagawa T; Saito Y; Saeki M; Sawada J; Tohkin M; Hasegawa R
    Drug Metab Dispos; 2005 Mar; 33(3):458-65. PubMed ID: 15572581
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intra-ethnic differences in genetic variants of the UGT-glucuronosyltransferase 1A1 gene in Chinese populations.
    Zhang A; Xing Q; Qin S; Du J; Wang L; Yu L; Li X; Xu L; Xu M; Feng G; He L
    Pharmacogenomics J; 2007 Oct; 7(5):333-8. PubMed ID: 17060921
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.
    Saito Y; Sai K; Maekawa K; Kaniwa N; Shirao K; Hamaguchi T; Yamamoto N; Kunitoh H; Ohe Y; Yamada Y; Tamura T; Yoshida T; Minami H; Ohtsu A; Matsumura Y; Saijo N; Sawada J
    Drug Metab Dispos; 2009 Feb; 37(2):272-6. PubMed ID: 18981166
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
    Innocenti F; Grimsley C; Das S; Ramírez J; Cheng C; Kuttab-Boulos H; Ratain MJ; Di Rienzo A
    Pharmacogenetics; 2002 Dec; 12(9):725-33. PubMed ID: 12464801
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
    Jinno H; Tanaka-Kagawa T; Hanioka N; Saeki M; Ishida S; Nishimura T; Ando M; Saito Y; Ozawa S; Sawada J
    Drug Metab Dispos; 2003 Jan; 31(1):108-13. PubMed ID: 12485959
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Haplotypes in the UGT1A1 gene and their role as genetic determinants of bilirubin concentration in healthy German volunteers.
    Borucki K; Weikert C; Fisher E; Jakubiczka S; Luley C; Westphal S; Dierkes J
    Clin Biochem; 2009 Nov; 42(16-17):1635-41. PubMed ID: 19732760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer.
    Sai K; Saeki M; Saito Y; Ozawa S; Katori N; Jinno H; Hasegawa R; Kaniwa N; Sawada J; Komamura K; Ueno K; Kamakura S; Kitakaze M; Kitamura Y; Kamatani N; Minami H; Ohtsu A; Shirao K; Yoshida T; Saijo N
    Clin Pharmacol Ther; 2004 Jun; 75(6):501-15. PubMed ID: 15179405
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bilirubin metabolism and UDP-glucuronosyltransferase 1A1 variants in Asians: Pathogenic implications and therapeutic response.
    Huang MJ; Chen PL; Huang CS
    Kaohsiung J Med Sci; 2022 Aug; 38(8):729-738. PubMed ID: 35942604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UDP-Glucuronosyltransferase 1A1 gene polymorphisms and total bilirubin levels in an ethnically diverse cohort of women.
    Hong AL; Huo D; Kim HJ; Niu Q; Fackenthal DL; Cummings SA; John EM; West DW; Whittemore AS; Das S; Olopade OI
    Drug Metab Dispos; 2007 Aug; 35(8):1254-61. PubMed ID: 17478602
    [TBL] [Abstract][Full Text] [Related]  

  • 10. UGT1A1*6, 1A7*3, and 1A9*22 genotypes predict severe neutropenia in FOLFIRI-treated metastatic colorectal cancer in two prospective studies in Japan.
    Hazama S; Mishima H; Tsunedomi R; Okuyama Y; Kato T; Takahashi K; Nozawa H; Ando H; Kobayashi M; Takemoto H; Nagata N; Kanekiyo S; Inoue Y; Hamamoto Y; Fujita Y; Hinoda Y; Okayama N; Oba K; Sakamoto J; Oka M
    Cancer Sci; 2013 Dec; 104(12):1662-9. PubMed ID: 24033692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
    Girard H; Villeneuve L; Court MH; Fortier LC; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
    Drug Metab Dispos; 2006 Jul; 34(7):1220-8. PubMed ID: 16595709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UDP-glucuronosyltransferase 1A1 (UGT1A1) gene haplotypes and their effect on serum bilirubin concentration in healthy Indian adults.
    D'Silva S; Colah RB; Ghosh K; Mukherjee MB
    Gene; 2013 Jan; 513(1):36-9. PubMed ID: 23147267
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.
    Villeneuve L; Girard H; Fortier LC; Gagné JF; Guillemette C
    J Pharmacol Exp Ther; 2003 Oct; 307(1):117-28. PubMed ID: 12944498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity.
    Kitagawa C; Ando M; Ando Y; Sekido Y; Wakai K; Imaizumi K; Shimokata K; Hasegawa Y
    Pharmacogenet Genomics; 2005 Jan; 15(1):35-41. PubMed ID: 15864124
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
    Wang H; Bian T; Jin T; Chen Y; Lin A; Chen C
    Pharmacogenomics; 2014 Apr; 15(6):785-98. PubMed ID: 24897286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.
    Court MH; Freytsis M; Wang X; Peter I; Guillemette C; Hazarika S; Duan SX; Greenblatt DJ; Lee WM;
    J Pharmacol Exp Ther; 2013 May; 345(2):297-307. PubMed ID: 23408116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distribution of the UGT1A1*28 polymorphism in Caucasian and Asian populations in the US: a genomic analysis of 138 healthy individuals.
    Liu JY; Qu K; Sferruzza AD; Bender RA
    Anticancer Drugs; 2007 Jul; 18(6):693-6. PubMed ID: 17762398
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UGT1A1 gene mutations and neonatal hyperbilirubinemia in Guangxi Heiyi Zhuang and Han populations.
    Wu XJ; Zhong DN; Xie XZ; Ye DZ; Gao ZY
    Pediatr Res; 2015 Nov; 78(5):585-8. PubMed ID: 26200705
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan.
    Innocenti F; Undevia SD; Iyer L; Chen PX; Das S; Kocherginsky M; Karrison T; Janisch L; Ramírez J; Rudin CM; Vokes EE; Ratain MJ
    J Clin Oncol; 2004 Apr; 22(8):1382-8. PubMed ID: 15007088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver.
    Li Y; Buckley D; Wang S; Klaassen CD; Zhong XB
    Drug Metab Dispos; 2009 Sep; 37(9):1978-86. PubMed ID: 19541828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.