246 related articles for article (PubMed ID: 15572593)
1. Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.
Bachmann PS; Gorman R; Mackenzie KL; Lutze-Mann L; Lock RB
Blood; 2005 Mar; 105(6):2519-26. PubMed ID: 15572593
[TBL] [Abstract][Full Text] [Related]
2. Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.
Bachmann PS; Gorman R; Papa RA; Bardell JE; Ford J; Kees UR; Marshall GM; Lock RB
Cancer Res; 2007 May; 67(9):4482-90. PubMed ID: 17483364
[TBL] [Abstract][Full Text] [Related]
3. Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells.
Jing D; Bhadri VA; Beck D; Thoms JA; Yakob NA; Wong JW; Knezevic K; Pimanda JE; Lock RB
Blood; 2015 Jan; 125(2):273-83. PubMed ID: 25336632
[TBL] [Abstract][Full Text] [Related]
4. Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.
Bachmann PS; Piazza RG; Janes ME; Wong NC; Davies C; Mogavero A; Bhadri VA; Szymanska B; Geninson G; Magistroni V; Cazzaniga G; Biondi A; Miranda-Saavedra D; Göttgens B; Saffery R; Craig JM; Marshall GM; Gambacorti-Passerini C; Pimanda JE; Lock RB
Blood; 2010 Oct; 116(16):3013-22. PubMed ID: 20647567
[TBL] [Abstract][Full Text] [Related]
5. [P38 mitogen-activated protein kinase mediates glucocorticoid receptor function induced by dexamethasone in acute lymphoblastic leukemia cells].
He L; Li D; Hou KZ; Liu YP
Zhonghua Er Ke Za Zhi; 2007 Sep; 45(9):687-91. PubMed ID: 18021564
[TBL] [Abstract][Full Text] [Related]
6. High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.
Catts VS; Farnsworth ML; Haber M; Norris MD; Lutze-Mann LH; Lock RB
Leukemia; 2001 Jun; 15(6):929-35. PubMed ID: 11417479
[TBL] [Abstract][Full Text] [Related]
7. Modulation of Glucocorticoid Resistance in Pediatric T-cell Acute Lymphoblastic Leukemia by Increasing BIM Expression with the PI3K/mTOR Inhibitor BEZ235.
Hall CP; Reynolds CP; Kang MH
Clin Cancer Res; 2016 Feb; 22(3):621-32. PubMed ID: 26080839
[TBL] [Abstract][Full Text] [Related]
8. Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.
Heidari N; Miller AV; Hicks MA; Marking CB; Harada H
Cell Death Dis; 2012 Jul; 3(7):e349. PubMed ID: 22825467
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia.
Bhadri VA; Cowley MJ; Kaplan W; Trahair TN; Lock RB
BMC Genomics; 2011 Nov; 12():565. PubMed ID: 22093874
[TBL] [Abstract][Full Text] [Related]
10. Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line.
Hosono N; Kishi S; Iho S; Urasaki Y; Yoshida A; Kurooka H; Yokota Y; Ueda T
Cancer Sci; 2010 Mar; 101(3):767-73. PubMed ID: 20067466
[TBL] [Abstract][Full Text] [Related]
11. Glycogen synthase kinase-3 plays a central role in mediating glucocorticoid-induced apoptosis.
Spokoini R; Kfir-Erenfeld S; Yefenof E; Sionov RV
Mol Endocrinol; 2010 Jun; 24(6):1136-50. PubMed ID: 20371704
[TBL] [Abstract][Full Text] [Related]
12. Glucocorticoids and selumetinib are highly synergistic in RAS pathway-mutated childhood acute lymphoblastic leukemia through upregulation of BIM.
Matheson EC; Thomas H; Case M; Blair H; Jackson RK; Masic D; Veal G; Halsey C; Newell DR; Vormoor J; Irving JAE
Haematologica; 2019 Sep; 104(9):1804-1811. PubMed ID: 30655370
[TBL] [Abstract][Full Text] [Related]
13. Involvement of miR17 pathway in glucocorticoid-induced cell death in pediatric acute lymphoblastic leukemia.
Harada M; Pokrovskaja-Tamm K; Söderhäll S; Heyman M; Grander D; Corcoran M
Leuk Lymphoma; 2012 Oct; 53(10):2041-50. PubMed ID: 22475310
[TBL] [Abstract][Full Text] [Related]
14. Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Real PJ; Tosello V; Palomero T; Castillo M; Hernando E; de Stanchina E; Sulis ML; Barnes K; Sawai C; Homminga I; Meijerink J; Aifantis I; Basso G; Cordon-Cardo C; Ai W; Ferrando A
Nat Med; 2009 Jan; 15(1):50-8. PubMed ID: 19098907
[TBL] [Abstract][Full Text] [Related]
15. Differential mRNA expression of glucocorticoid receptor alpha and beta is associated with glucocorticoid sensitivity of acute lymphoblastic leukemia in children.
Koga Y; Matsuzaki A; Suminoe A; Hattori H; Kanemitsu S; Hara T
Pediatr Blood Cancer; 2005 Aug; 45(2):121-7. PubMed ID: 15704223
[TBL] [Abstract][Full Text] [Related]
16. Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.
Liem NL; Papa RA; Milross CG; Schmid MA; Tajbakhsh M; Choi S; Ramirez CD; Rice AM; Haber M; Norris MD; MacKenzie KL; Lock RB
Blood; 2004 May; 103(10):3905-14. PubMed ID: 14764536
[TBL] [Abstract][Full Text] [Related]
17. [Effect of glucocorticoid on the expression of Puma in acute lymphoblastic leukemia].
Xu B; Wang BJ; Li AM; Lock R
Zhongguo Dang Dai Er Ke Za Zhi; 2006 Apr; 8(2):151-4. PubMed ID: 16613713
[TBL] [Abstract][Full Text] [Related]
18. In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature.
Haarman EG; Kaspers GJ; Pieters R; Rottier MM; Den Boer ML; Janka-Schaub GE; Veerman AJ
Leukemia; 2002 Sep; 16(9):1882-4. PubMed ID: 12200716
[No Abstract] [Full Text] [Related]
19. Quantitative analysis and modeling of glucocorticoid-controlled gene expression.
Chen DW; Lynch JT; Demonacos C; Krstic-Demonacos M; Schwartz JM
Pharmacogenomics; 2010 Nov; 11(11):1545-60. PubMed ID: 21121775
[TBL] [Abstract][Full Text] [Related]
20. Glucocorticoid-induced apoptosis and glucocorticoid resistance in acute lymphoblastic leukemia.
Ploner C; Schmidt S; Presul E; Renner K; Schröcksnadel K; Rainer J; Riml S; Kofler R
J Steroid Biochem Mol Biol; 2005 Feb; 93(2-5):153-60. PubMed ID: 15860257
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]