BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

336 related articles for article (PubMed ID: 15574785)

  • 1. The prosurvival activity of p53 protects cells from UV-induced apoptosis by inhibiting c-Jun NH2-terminal kinase activity and mitochondrial death signaling.
    Lo PK; Huang SZ; Chen HC; Wang FF
    Cancer Res; 2004 Dec; 64(23):8736-45. PubMed ID: 15574785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
    Hsu YL; Cho CY; Kuo PL; Huang YT; Lin CC
    J Pharmacol Exp Ther; 2006 Aug; 318(2):484-94. PubMed ID: 16632641
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53.
    Hildesheim J; Bulavin DV; Anver MR; Alvord WG; Hollander MC; Vardanian L; Fornace AJ
    Cancer Res; 2002 Dec; 62(24):7305-15. PubMed ID: 12499274
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanisms underlying the pro-survival pathway of p53 in suppressing mitotic death induced by adriamycin.
    Lin YC; Wang FF
    Cell Signal; 2008 Jan; 20(1):258-67. PubMed ID: 18006273
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine.
    Fan M; Goodwin ME; Birrer MJ; Chambers TC
    Cancer Res; 2001 Jun; 61(11):4450-8. PubMed ID: 11389075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis in UV-C light irradiated p53 wild-type, apaf-1 and p53 knockout mouse embryonic fibroblasts: interplay of receptor and mitochondrial pathway.
    Tomicic MT; Christmann M; Kaina B
    Apoptosis; 2005 Dec; 10(6):1295-304. PubMed ID: 16215690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.
    Kim MJ; Lee KH; Lee SJ
    FEBS J; 2008 May; 275(9):2096-108. PubMed ID: 18373696
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1.
    Gulati AP; Yang YM; Harter D; Mukhopadhyay A; Aggarwal BB; Benzil DL; Whysner J; Albino AP; Murali R; Jhanwar-Uniyal M
    Mol Carcinog; 2006 Jan; 45(1):26-37. PubMed ID: 16267831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Moscatilin induces apoptosis in human colorectal cancer cells: a crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage.
    Chen TH; Pan SL; Guh JH; Liao CH; Huang DY; Chen CC; Teng CM
    Clin Cancer Res; 2008 Jul; 14(13):4250-8. PubMed ID: 18594007
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of caspase-3 and a caffeine-inhibitable event.
    Essmann F; Engels IH; Totzke G; Schulze-Osthoff K; Jänicke RU
    Cancer Res; 2004 Oct; 64(19):7065-72. PubMed ID: 15466201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proton induces apoptosis of hypoxic tumor cells by the p53-dependent and p38/JNK MAPK signaling pathways.
    Lee KB; Kim KR; Huh TL; Lee YM
    Int J Oncol; 2008 Dec; 33(6):1247-56. PubMed ID: 19020758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways in human breast cancer cells.
    Hsu YL; Kuo PL; Lin LT; Lin CC
    J Pharmacol Exp Ther; 2005 Apr; 313(1):333-44. PubMed ID: 15626723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells.
    Cheng Y; Qiu F; Ye YC; Tashiro S; Onodera S; Ikejima T
    Arch Biochem Biophys; 2009 Oct; 490(1):70-5. PubMed ID: 19699177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of tumor suppressor p53 facilitates DNA repair but not UV-induced G2/M arrest or apoptosis in Chinese hamster ovary CHO-K1 cells.
    Chang YC; Liao CB; Hsieh PY; Liou ML; Liu YC
    J Cell Biochem; 2008 Feb; 103(2):528-37. PubMed ID: 17549699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. c-Jun N-terminal kinase regulates apoptosis in endometrial cancer cells.
    Reno EM; Haughian JM; Jackson TA; Thorne AM; Bradford AP
    Apoptosis; 2009 Jun; 14(6):809-20. PubMed ID: 19424800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A role for UV-light-induced c-Fos: Stimulation of nucleotide excision repair and protection against sustained JNK activation and apoptosis.
    Christmann M; Tomicic MT; Aasland D; Kaina B
    Carcinogenesis; 2007 Jan; 28(1):183-90. PubMed ID: 16829684
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone deacetylase 5 is not a p53 target gene, but its overexpression inhibits tumor cell growth and induces apoptosis.
    Huang Y; Tan M; Gosink M; Wang KK; Sun Y
    Cancer Res; 2002 May; 62(10):2913-22. PubMed ID: 12019172
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis.
    de Belle I; Huang RP; Fan Y; Liu C; Mercola D; Adamson ED
    Oncogene; 1999 Jun; 18(24):3633-42. PubMed ID: 10380885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.
    Vesely DL; Hoffman B; Liebermann DA
    Oncogene; 2007 May; 26(21):3041-50. PubMed ID: 17099722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of correlation in JNK activation and p53-dependent Fas expression induced by apoptotic stimuli.
    Chen YR; Tan TH
    Biochem Biophys Res Commun; 1999 Mar; 256(3):595-9. PubMed ID: 10080943
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.