BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 15576447)

  • 1. The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity.
    Cheung C; Yu AM; Ward JM; Krausz KW; Akiyama TE; Feigenbaum L; Gonzalez FJ
    Drug Metab Dispos; 2005 Mar; 33(3):449-57. PubMed ID: 15576447
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.
    Zaher H; Buters JT; Ward JM; Bruno MK; Lucas AM; Stern ST; Cohen SD; Gonzalez FJ
    Toxicol Appl Pharmacol; 1998 Sep; 152(1):193-9. PubMed ID: 9772215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage.
    Morgan K; French SW; Morgan TR
    Hepatology; 2002 Jul; 36(1):122-34. PubMed ID: 12085356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes.
    Jemnitz K; Veres Z; Monostory K; Kóbori L; Vereczkey L
    Toxicol In Vitro; 2008 Jun; 22(4):961-7. PubMed ID: 18346862
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dietary steatotic liver attenuates acetaminophen hepatotoxicity in mice.
    Ito Y; Abril ER; Bethea NW; McCuskey MK; McCuskey RS
    Microcirculation; 2006 Jan; 13(1):19-27. PubMed ID: 16393943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetaminophen induced acute liver failure via oxidative stress and JNK activation: protective role of taurine by the suppression of cytochrome P450 2E1.
    Das J; Ghosh J; Manna P; Sil PC
    Free Radic Res; 2010 Mar; 44(3):340-55. PubMed ID: 20166895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity.
    Snawder JE; Roe AL; Benson RW; Roberts DW
    Biochem Biophys Res Commun; 1994 Aug; 203(1):532-9. PubMed ID: 8074700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in Cyp2e1(-/-) mice.
    Sinclair JF; Szakacs JG; Wood SG; Walton HS; Bement JL; Gonzalez FJ; Jeffery EH; Wrighton SA; Bement WJ; Sinclair PR
    Toxicol Appl Pharmacol; 2000 Oct; 168(2):114-22. PubMed ID: 11032766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Xenobiotic-enhanced expression of cytochromes P450 2E1 and 2B in primary cultured rat hepatocytes.
    Woodcroft KJ; Novak RF
    Drug Metab Dispos; 1998 Apr; 26(4):372-8. PubMed ID: 9531527
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ethanol-inducible cytochrome P4502E1: regulation, enzymology and molecular biology.
    Ingelman-Sundberg M; Ronis MJ; Lindros KO; Eliasson E; Zhukov A
    Alcohol Alcohol Suppl; 1994; 2():131-9. PubMed ID: 8974327
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.
    Hanioka N; Yamamoto M; Iwabu H; Jinno H; Tanaka-Kagawa T; Naito S; Shimizu T; Masuda K; Katsu T; Narimatsu S
    Life Sci; 2007 Oct; 81(19-20):1436-45. PubMed ID: 17935737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen.
    Knockaert L; Descatoire V; Vadrot N; Fromenty B; Robin MA
    Toxicol In Vitro; 2011 Mar; 25(2):475-84. PubMed ID: 21130154
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of human cytochromes P450 in chimeric mice with humanized liver.
    Katoh M; Matsui T; Nakajima M; Tateno C; Kataoka M; Soeno Y; Horie T; Iwasaki K; Yoshizato K; Yokoi T
    Drug Metab Dispos; 2004 Dec; 32(12):1402-10. PubMed ID: 15383493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolic basis of ethanol-induced cytotoxicity in recombinant HepG2 cells: role of nonoxidative metabolism.
    Wu H; Cai P; Clemens DL; Jerrells TR; Ansari GA; Kaphalia BS
    Toxicol Appl Pharmacol; 2006 Oct; 216(2):238-47. PubMed ID: 16806343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein.
    Ghosh A; Sil PC
    Chem Biol Interact; 2009 Jan; 177(2):96-106. PubMed ID: 18835260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CYP2E1--biochemical and toxicological aspects and role in alcohol-induced liver injury.
    Cederbaum AI
    Mt Sinai J Med; 2006 Jul; 73(4):657-72. PubMed ID: 16878272
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity.
    Kang JS; Wanibuchi H; Morimura K; Wongpoomchai R; Chusiri Y; Gonzalez FJ; Fukushima S
    Toxicol Appl Pharmacol; 2008 May; 228(3):295-300. PubMed ID: 18374380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human hepatocytes can repopulate mouse liver: histopathology of the liver in human hepatocyte-transplanted chimeric mice and toxicologic responses to acetaminophen.
    Sato Y; Yamada H; Iwasaki K; Tateno C; Yokoi T; Yoshizato K; Horii I
    Toxicol Pathol; 2008 Jun; 36(4):581-91. PubMed ID: 18467679
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes.
    Robin MA; Sauvage I; Grandperret T; Descatoire V; Pessayre D; Fromenty B
    FEBS Lett; 2005 Dec; 579(30):6895-902. PubMed ID: 16337197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine.
    Caro AA; Cederbaum AI
    Biochem Pharmacol; 2005 Apr; 69(7):1081-93. PubMed ID: 15763544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.