183 related articles for article (PubMed ID: 15579109)
1. In silico methods for predicting ligand binding determinants of cytochromes P450.
de Groot MJ; Kirton SB; Sutcliffe MJ
Curr Top Med Chem; 2004; 4(16):1803-24. PubMed ID: 15579109
[TBL] [Abstract][Full Text] [Related]
2. Designing better drugs: predicting cytochrome P450 metabolism.
de Groot MJ
Drug Discov Today; 2006 Jul; 11(13-14):601-6. PubMed ID: 16793528
[TBL] [Abstract][Full Text] [Related]
3. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.
Dong D; Wu B
Drug Metab Rev; 2012 Feb; 44(1):1-17. PubMed ID: 22242930
[TBL] [Abstract][Full Text] [Related]
4. Toward Computational Understanding of Molecular Recognition in the Human Metabolizing Cytochrome P450s.
Kontoyianni M; Lacy B
Curr Med Chem; 2018; 25(28):3353-3373. PubMed ID: 29484977
[TBL] [Abstract][Full Text] [Related]
5. Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.
Dong D; Wu B; Chow D; Hu M
Drug Metab Rev; 2012 May; 44(2):192-208. PubMed ID: 22251142
[TBL] [Abstract][Full Text] [Related]
6. Pharmacophore modeling of cytochromes P450.
de Groot MJ; Ekins S
Adv Drug Deliv Rev; 2002 Mar; 54(3):367-83. PubMed ID: 11922953
[TBL] [Abstract][Full Text] [Related]
7. Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.
Lewis DF; Ito Y
Xenobiotica; 2009 Aug; 39(8):625-35. PubMed ID: 19514836
[TBL] [Abstract][Full Text] [Related]
8. Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modeling.
Wang Q; Halpert JR
Drug Metab Dispos; 2002 Jan; 30(1):86-95. PubMed ID: 11744616
[TBL] [Abstract][Full Text] [Related]
9. Predicting the cytochrome P450 mediated metabolism of xenobiotics.
Korzekwa KR; Jones JP
Pharmacogenetics; 1993 Feb; 3(1):1-18. PubMed ID: 8485584
[TBL] [Abstract][Full Text] [Related]
10. Computational methods and tools to predict cytochrome P450 metabolism for drug discovery.
Tyzack JD; Kirchmair J
Chem Biol Drug Des; 2019 Apr; 93(4):377-386. PubMed ID: 30471192
[TBL] [Abstract][Full Text] [Related]
11. Comparative modelling of cytochromes P450.
Kirton SB; Baxter CA; Sutcliffe MJ
Adv Drug Deliv Rev; 2002 Mar; 54(3):385-406. PubMed ID: 11922954
[TBL] [Abstract][Full Text] [Related]
12. In silico prediction of cytochrome P450-mediated site of metabolism (SOM).
Liu X; Shen Q; Li J; Li S; Luo C; Zhu W; Luo X; Zheng M; Jiang H
Protein Pept Lett; 2013 Mar; 20(3):279-89. PubMed ID: 22591483
[TBL] [Abstract][Full Text] [Related]
13. Compound lipophilicity for substrate binding to human P450s in drug metabolism.
Lewis DF; Jacobs MN; Dickins M
Drug Discov Today; 2004 Jun; 9(12):530-7. PubMed ID: 15183161
[TBL] [Abstract][Full Text] [Related]
14. Computational prediction of drug binding and rationalisation of selectivity towards cytochromes P450.
Stjernschantz E; Vermeulen NP; Oostenbrink C
Expert Opin Drug Metab Toxicol; 2008 May; 4(5):513-27. PubMed ID: 18484912
[TBL] [Abstract][Full Text] [Related]
15. Modelling cytochromes P450 binding modes to predict P450 inhibition, metabolic stability and isoform selectivity.
Carosati E
Drug Discov Today Technol; 2013; 10(1):e167-75. PubMed ID: 24050246
[TBL] [Abstract][Full Text] [Related]
16. Towards Predicting the Cytochrome P450 Modulation: From QSAR to Proteochemometric Modeling.
Shoombuatong W; Prathipati P; Prachayasittikul V; Schaduangrat N; Malik AA; Pratiwi R; Wanwimolruk S; Wikberg JES; Gleeson MP; Spjuth O; Nantasenamat C
Curr Drug Metab; 2017 Jul; 18(6):540-555. PubMed ID: 28322159
[TBL] [Abstract][Full Text] [Related]
17. Computational identification and binding analysis of orphan human cytochrome P450 4X1 enzyme with substrates.
Kumar S
BMC Res Notes; 2015 Jan; 8():9. PubMed ID: 25595103
[TBL] [Abstract][Full Text] [Related]
18. In silico predictive metabolism: a structural/electronic filter method.
Harris DL
Curr Opin Drug Discov Devel; 2004 Jan; 7(1):43-8. PubMed ID: 14982147
[TBL] [Abstract][Full Text] [Related]
19. The human hepatic cytochromes P450 involved in drug metabolism.
Wrighton SA; Stevens JC
Crit Rev Toxicol; 1992; 22(1):1-21. PubMed ID: 1616599
[TBL] [Abstract][Full Text] [Related]
20. Toward reduction in animal sacrifice for drugs: molecular modeling of Macaca fascicularis P450 2C20 for virtual screening of Homo sapiens P450 2C8 substrates.
Rua F; Di Nardo G; Sadeghi SJ; Gilardi G
Biotechnol Appl Biochem; 2012; 59(6):479-89. PubMed ID: 23586958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]