BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 15586242)

  • 1. Hypoxia-responsive element-mediated soluble Tie2 vector exhibits an anti-angiogenic activity in vitro under hypoxic condition.
    Jeong CH; Lee YM; Choi KS; Seong YR; Kim YJ; Im DS; Kim KW
    Int J Oncol; 2005 Jan; 26(1):211-6. PubMed ID: 15586242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulated hypoxia-inducible factor-1 DNA binding activity to the vascular endothelial growth factor-A promoter mediates increased vascular permeability in donor lung grafts.
    Abraham D; Krenn K; Seebacher G; Paulus P; Klepetko W; Aharinejad S
    Ann Thorac Surg; 2004 May; 77(5):1751-5. PubMed ID: 15111179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.
    Takeda N; Maemura K; Imai Y; Harada T; Kawanami D; Nojiri T; Manabe I; Nagai R
    Circ Res; 2004 Jul; 95(2):146-53. PubMed ID: 15192019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A; Uranchimeg B; Scudiero DA; Selby M; Sausville EA; Shoemaker RH; Melillo G
    Cancer Res; 2002 Aug; 62(15):4316-24. PubMed ID: 12154035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a hypoxia-responsive vector for tumor-specific gene therapy.
    Shibata T; Giaccia AJ; Brown JM
    Gene Ther; 2000 Mar; 7(6):493-8. PubMed ID: 10757022
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia--a key regulatory factor in tumour growth.
    Harris AL
    Nat Rev Cancer; 2002 Jan; 2(1):38-47. PubMed ID: 11902584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression.
    Makino Y; Cao R; Svensson K; Bertilsson G; Asman M; Tanaka H; Cao Y; Berkenstam A; Poellinger L
    Nature; 2001 Nov; 414(6863):550-4. PubMed ID: 11734856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Subcellular localization and regulation of hypoxia-inducible factor-2alpha in vascular endothelial cells.
    Takahashi R; Kobayashi C; Kondo Y; Nakatani Y; Kudo I; Kunimoto M; Imura N; Hara S
    Biochem Biophys Res Commun; 2004 Apr; 317(1):84-91. PubMed ID: 15047151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-angiogenic effects of ribonucleic acid interference targeting vascular endothelial growth factor and hypoxia-inducible factor-1alpha.
    Forooghian F; Das B
    Am J Ophthalmol; 2007 Nov; 144(5):761-8. PubMed ID: 17869204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A.
    Detwiller KY; Fernando NT; Segal NH; Ryeom SW; D'Amore PA; Yoon SS
    Cancer Res; 2005 Jul; 65(13):5881-9. PubMed ID: 15994966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Repression of alpha-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc.
    Mazure NM; Chauvet C; Bois-Joyeux B; Bernard MA; Nacer-Chérif H; Danan JL
    Cancer Res; 2002 Feb; 62(4):1158-65. PubMed ID: 11861398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding and regulation of hypoxia-inducible factor-1 by the inhibitory PAS proteins.
    Jang MS; Park JE; Lee JA; Park SG; Myung PK; Lee DH; Park BC; Cho S
    Biochem Biophys Res Commun; 2005 Nov; 337(1):209-15. PubMed ID: 16182248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of VEGF transcription in renal cell carcinoma cells by pyrrole-imidazole hairpin polyamides targeting the hypoxia responsive element.
    Kageyama Y; Sugiyama H; Ayame H; Iwai A; Fujii Y; Huang LE; Kizaka-Kondoh S; Hiraoka M; Kihara K
    Acta Oncol; 2006; 45(3):317-24. PubMed ID: 16644575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression.
    Sato F; Bhawal UK; Kawamoto T; Fujimoto K; Imaizumi T; Imanaka T; Kondo J; Koyanagi S; Noshiro M; Yoshida H; Kusumi T; Kato Y; Kijima H
    Genes Cells; 2008 Feb; 13(2):131-44. PubMed ID: 18233956
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diosgenin induces hypoxia-inducible factor-1 activation and angiogenesis through estrogen receptor-related phosphatidylinositol 3-kinase/Akt and p38 mitogen-activated protein kinase pathways in osteoblasts.
    Yen ML; Su JL; Chien CL; Tseng KW; Yang CY; Chen WF; Chang CC; Kuo ML
    Mol Pharmacol; 2005 Oct; 68(4):1061-73. PubMed ID: 15998873
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene.
    Ziel KA; Campbell CC; Wilson GL; Gillespie MN
    FASEB J; 2004 Jun; 18(9):986-8. PubMed ID: 15084519
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Effect of silencing HIF-1alpha by RNA interference on expression of vascular endothelial growth factor in osteosarcoma cell line SaOS-2 under hypoxia].
    Wu Q; Yang SH; Wang RY; Ye SN; Xia T; Ma DZ
    Ai Zheng; 2005 May; 24(5):531-5. PubMed ID: 15890092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Herpes simplex virus amplicon delivery of a hypoxia-inducible soluble vascular endothelial growth factor receptor (sFlk-1) inhibits angiogenesis and tumor growth in pancreatic adenocarcinoma.
    Reinblatt M; Pin RH; Bowers WJ; Federoff HJ; Fong Y
    Ann Surg Oncol; 2005 Dec; 12(12):1025-36. PubMed ID: 16244806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Does endogenous fatty acid metabolism allow cancer cells to sense hypoxia and mediate hypoxic vasodilatation? Characterization of a novel molecular connection between fatty acid synthase (FAS) and hypoxia-inducible factor-1alpha (HIF-1alpha)-related expression of vascular endothelial growth factor (VEGF) in cancer cells overexpressing her-2/neu oncogene.
    Menendez JA; Vellon L; Oza BP; Lupu R
    J Cell Biochem; 2005 Apr; 94(5):857-63. PubMed ID: 15669079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NERF2, a member of the Ets family of transcription factors, is increased in response to hypoxia and angiopoietin-1: a potential mechanism for Tie2 regulation during hypoxia.
    Christensen RA; Fujikawa K; Madore R; Oettgen P; Varticovski L
    J Cell Biochem; 2002; 85(3):505-15. PubMed ID: 11967990
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.