146 related articles for article (PubMed ID: 15587776)
1. NXY-059: a neuroprotective agent in acute stroke.
Wang CX; Shuaib A
Int J Clin Pract; 2004 Oct; 58(10):964-9. PubMed ID: 15587776
[TBL] [Abstract][Full Text] [Related]
2. Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator.
Lapchak PA; Araujo DM; Song D; Wei J; Zivin JA
Stroke; 2002 May; 33(5):1411-5. PubMed ID: 11988623
[TBL] [Abstract][Full Text] [Related]
3. Effects of the spin trap agent disodium- [tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit Large clot embolic stroke model: combination studies with tissue plasminogen activator.
Lapchak PA; Araujo DM; Song D; Wei J; Purdy R; Zivin JA
Stroke; 2002 Jun; 33(6):1665-70. PubMed ID: 12053009
[TBL] [Abstract][Full Text] [Related]
4. Development of the nitrone-based spin trap agent NXY-059 to treat acute ischemic stroke.
Lapchak PA; Araujo DM
CNS Drug Rev; 2003; 9(3):253-62. PubMed ID: 14530797
[TBL] [Abstract][Full Text] [Related]
5. Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke.
Peeling J; Del Bigio MR; Corbett D; Green AR; Jackson DM
Neuropharmacology; 2001 Mar; 40(3):433-9. PubMed ID: 11166336
[TBL] [Abstract][Full Text] [Related]
6. Nitrone-related therapeutics: potential of NXY-059 for the treatment of acute ischaemic stroke.
Maples KR; Green AR; Floyd RA
CNS Drugs; 2004; 18(15):1071-84. PubMed ID: 15581379
[TBL] [Abstract][Full Text] [Related]
7. NXY-059: review of neuroprotective potential for acute stroke.
Fong JJ; Rhoney DH
Ann Pharmacother; 2006 Mar; 40(3):461-71. PubMed ID: 16507608
[TBL] [Abstract][Full Text] [Related]
8. Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059.
Green AR; Ashwood T; Odergren T; Jackson DM
Pharmacol Ther; 2003 Dec; 100(3):195-214. PubMed ID: 14652110
[TBL] [Abstract][Full Text] [Related]
9. Coadministration of NXY-059 and tenecteplase six hours following embolic strokes in rabbits improves clinical rating scores.
Lapchak PA; Song D; Wei J; Zivin JA
Exp Neurol; 2004 Aug; 188(2):279-85. PubMed ID: 15246827
[TBL] [Abstract][Full Text] [Related]
10. Tolerability and pharmacokinetics of the nitrone NXY-059 in patients with acute stroke.
Lees KR; Sharma AK; Barer D; Ford GA; Kostulas V; Cheng YF; Odergren T
Stroke; 2001 Mar; 32(3):675-80. PubMed ID: 11239186
[TBL] [Abstract][Full Text] [Related]
11. Neuroprotective effects of free radical scavengers in stroke.
Wang CX; Shuaib A
Drugs Aging; 2007; 24(7):537-46. PubMed ID: 17658905
[TBL] [Abstract][Full Text] [Related]
12. NXY-059. Centaur.
Lapchak PA
Curr Opin Investig Drugs; 2002 Dec; 3(12):1758-62. PubMed ID: 12528313
[TBL] [Abstract][Full Text] [Related]
13. Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat.
Kuroda S; Tsuchidate R; Smith ML; Maples KR; Siesjö BK
J Cereb Blood Flow Metab; 1999 Jul; 19(7):778-87. PubMed ID: 10413033
[TBL] [Abstract][Full Text] [Related]
14. NXY-059 for acute ischemic stroke.
Lees KR; Zivin JA; Ashwood T; Davalos A; Davis SM; Diener HC; Grotta J; Lyden P; Shuaib A; Hårdemark HG; Wasiewski WW;
N Engl J Med; 2006 Feb; 354(6):588-600. PubMed ID: 16467546
[TBL] [Abstract][Full Text] [Related]
15. NXY-059, a nitrone with free radical trapping properties inhibits release of cytochrome c after focal cerebral ischemia.
Han M; He QP; Yong G; Siesjö BK; Li PA
Cell Mol Biol (Noisy-le-grand); 2003 Dec; 49(8):1249-52. PubMed ID: 14983994
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetics in renally impaired subjects of NXY-059, a nitrone-based, free-radical trapping agent developed for the treatment of acute stroke.
Strid S; Borgå O; Edenius C; Jostell KG; Odergren T; Weil A
Eur J Clin Pharmacol; 2002 Sep; 58(6):409-15. PubMed ID: 12242600
[TBL] [Abstract][Full Text] [Related]
17. In vitro blood-brain barrier permeability and cerebral endothelial cell uptake of the neuroprotective nitrone compound NXY-059 in normoxic, hypoxic and ischemic conditions.
Dehouck MP; Cecchelli R; Richard Green A; Renftel M; Lundquist S
Brain Res; 2002 Nov; 955(1-2):229-35. PubMed ID: 12419541
[TBL] [Abstract][Full Text] [Related]
18. Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers.
Green AR; Ashwood T
Curr Drug Targets CNS Neurol Disord; 2005 Apr; 4(2):109-18. PubMed ID: 15857295
[TBL] [Abstract][Full Text] [Related]
19. NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat.
Zhao Z; Cheng M; Maples KR; Ma JY; Buchan AM
Brain Res; 2001 Aug; 909(1-2):46-50. PubMed ID: 11478919
[TBL] [Abstract][Full Text] [Related]
20. Tolerability of NXY-059 at higher target concentrations in patients with acute stroke.
Lees KR; Barer D; Ford GA; Hacke W; Kostulas V; Sharma AK; Odergren T;
Stroke; 2003 Feb; 34(2):482-7. PubMed ID: 12574564
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]