These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 15591046)

  • 1. beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein.
    Snyder H; Mensah K; Hsu C; Hashimoto M; Surgucheva IG; Festoff B; Surguchov A; Masliah E; Matouschek A; Wolozin B
    J Biol Chem; 2005 Mar; 280(9):7562-9. PubMed ID: 15591046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function.
    Snyder H; Mensah K; Theisler C; Lee J; Matouschek A; Wolozin B
    J Biol Chem; 2003 Apr; 278(14):11753-9. PubMed ID: 12551928
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteasomal inhibition by alpha-synuclein filaments and oligomers.
    Lindersson E; Beedholm R; Højrup P; Moos T; Gai W; Hendil KB; Jensen PH
    J Biol Chem; 2004 Mar; 279(13):12924-34. PubMed ID: 14711827
    [TBL] [Abstract][Full Text] [Related]  

  • 4. alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome.
    Tofaris GK; Layfield R; Spillantini MG
    FEBS Lett; 2001 Nov; 509(1):22-6. PubMed ID: 11734199
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathological proteins in Parkinson's disease: focus on the proteasome.
    Snyder H; Wolozin B
    J Mol Neurosci; 2004; 24(3):425-42. PubMed ID: 15655264
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins.
    Uversky VN; Li J; Souillac P; Millett IS; Doniach S; Jakes R; Goedert M; Fink AL
    J Biol Chem; 2002 Apr; 277(14):11970-8. PubMed ID: 11812782
    [TBL] [Abstract][Full Text] [Related]  

  • 7. alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.
    Zhang NY; Tang Z; Liu CW
    J Biol Chem; 2008 Jul; 283(29):20288-98. PubMed ID: 18502751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. alpha-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.
    Martìn-Clemente B; Alvarez-Castelao B; Mayo I; Sierra AB; Dìaz V; Milán M; Fariñas I; Gómez-Isla T; Ferrer I; Castaño JG
    J Biol Chem; 2004 Dec; 279(51):52984-90. PubMed ID: 15466467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines.
    Alvarez-Castelao B; Goethals M; Vandekerckhove J; Castaño JG
    Biochim Biophys Acta; 2014 Feb; 1843(2):352-65. PubMed ID: 24315858
    [TBL] [Abstract][Full Text] [Related]  

  • 10. E3 ubiquitin ligase RNF2 interacts with the S6' proteasomal ATPase subunit and increases the ATP hydrolysis activity of S6'.
    Lee SJ; Choi D; Rhim H; Kang S
    Biochem J; 2005 Jul; 389(Pt 2):457-63. PubMed ID: 15773819
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains.
    Doss-Pepe EW; Chen L; Madura K
    J Biol Chem; 2005 Apr; 280(17):16619-24. PubMed ID: 15718234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of alpha-synuclein aggregation by intracellular nitrative insult.
    Paxinou E; Chen Q; Weisse M; Giasson BI; Norris EH; Rueter SM; Trojanowski JQ; Lee VM; Ischiropoulos H
    J Neurosci; 2001 Oct; 21(20):8053-61. PubMed ID: 11588178
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Accumulation of beta- and gamma-synucleins in the ubiquitin carboxyl-terminal hydrolase L1-deficient gad mouse.
    Wang YL; Takeda A; Osaka H; Hara Y; Furuta A; Setsuie R; Sun YJ; Kwon J; Sato Y; Sakurai M; Noda M; Yoshikawa Y; Wada K
    Brain Res; 2004 Sep; 1019(1-2):1-9. PubMed ID: 15306232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways.
    Shin Y; Klucken J; Patterson C; Hyman BT; McLean PJ
    J Biol Chem; 2005 Jun; 280(25):23727-34. PubMed ID: 15845543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival.
    Lee G; Junn E; Tanaka M; Kim YM; Mouradian MM
    J Neurochem; 2002 Oct; 83(2):346-52. PubMed ID: 12423244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease.
    Liu CW; Giasson BI; Lewis KA; Lee VM; Demartino GN; Thomas PJ
    J Biol Chem; 2005 Jun; 280(24):22670-8. PubMed ID: 15840579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells.
    Ancolio K; Alves da Costa C; Uéda K; Checler F
    Neurosci Lett; 2000 May; 285(2):79-82. PubMed ID: 10793231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
    Stefanis L; Larsen KE; Rideout HJ; Sulzer D; Greene LA
    J Neurosci; 2001 Dec; 21(24):9549-60. PubMed ID: 11739566
    [TBL] [Abstract][Full Text] [Related]  

  • 19. UCH-L1 aggresome formation in response to proteasome impairment indicates a role in inclusion formation in Parkinson's disease.
    Ardley HC; Scott GB; Rose SA; Tan NG; Robinson PA
    J Neurochem; 2004 Jul; 90(2):379-91. PubMed ID: 15228595
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells.
    Rideout HJ; Larsen KE; Sulzer D; Stefanis L
    J Neurochem; 2001 Aug; 78(4):899-908. PubMed ID: 11520910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.