471 related articles for article (PubMed ID: 15592418)
1. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
Mao JH; Perez-Losada J; Wu D; Delrosario R; Tsunematsu R; Nakayama KI; Brown K; Bryson S; Balmain A
Nature; 2004 Dec; 432(7018):775-9. PubMed ID: 15592418
[TBL] [Abstract][Full Text] [Related]
2. FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
Cancer Res; 2007 Oct; 67(19):9006-12. PubMed ID: 17909001
[TBL] [Abstract][Full Text] [Related]
3. CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
Kemp Z; Rowan A; Chambers W; Wortham N; Halford S; Sieber O; Mortensen N; von Herbay A; Gunther T; Ilyas M; Tomlinson I
Cancer Res; 2005 Dec; 65(24):11361-6. PubMed ID: 16357143
[TBL] [Abstract][Full Text] [Related]
4. Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiation-induced mouse thymic lymphomas.
Snijders AM; Liu Y; Su L; Huang Y; Mao JH
Oncotarget; 2015 Dec; 6(42):44794-805. PubMed ID: 26575021
[TBL] [Abstract][Full Text] [Related]
5. Recombinant human adenovirus-p53 injection induced apoptosis in hepatocellular carcinoma cell lines mediated by p53-Fbxw7 pathway, which controls c-Myc and cyclin E.
Tu K; Zheng X; Zhou Z; Li C; Zhang J; Gao J; Yao Y; Liu Q
PLoS One; 2013; 8(7):e68574. PubMed ID: 23840897
[TBL] [Abstract][Full Text] [Related]
6. Loss of CDC4/FBXW7 in gastric carcinoma.
Milne AN; Leguit R; Corver WE; Morsink FH; Polak M; de Leng WW; Carvalho R; Offerhaus GJ
Cell Oncol; 2010; 32(5-6):347-59. PubMed ID: 20448329
[TBL] [Abstract][Full Text] [Related]
7. Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway.
Perez-Losada J; Mao JH; Balmain A
Cancer Res; 2005 Aug; 65(15):6488-92. PubMed ID: 16061623
[TBL] [Abstract][Full Text] [Related]
8. Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner.
Matsumoto A; Onoyama I; Nakayama KI
Biochem Biophys Res Commun; 2006 Nov; 350(1):114-9. PubMed ID: 16989775
[TBL] [Abstract][Full Text] [Related]
9. FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors.
Kitade S; Onoyama I; Kobayashi H; Yagi H; Yoshida S; Kato M; Tsunematsu R; Asanoma K; Sonoda K; Wake N; Hata K; Nakayama KI; Kato K
Cancer Sci; 2016 Oct; 107(10):1399-1405. PubMed ID: 27486687
[TBL] [Abstract][Full Text] [Related]
10. The Fbxw7/hCdc4 tumor suppressor in human cancer.
Tan Y; Sangfelt O; Spruck C
Cancer Lett; 2008 Nov; 271(1):1-12. PubMed ID: 18541364
[TBL] [Abstract][Full Text] [Related]
11. FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15.
Li N; Lorenzi F; Kalakouti E; Normatova M; Babaei-Jadidi R; Tomlinson I; Nateri AS
Oncotarget; 2015 Apr; 6(11):9240-56. PubMed ID: 25860929
[TBL] [Abstract][Full Text] [Related]
12. Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch.
Ishikawa Y; Hosogane M; Okuyama R; Aoyama S; Onoyama I; Nakayama KI; Nakayama K
Oncogene; 2013 Apr; 32(15):1921-32. PubMed ID: 22665065
[TBL] [Abstract][Full Text] [Related]
13. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis.
Onoyama I; Tsunematsu R; Matsumoto A; Kimura T; de Alborán IM; Nakayama K; Nakayama KI
J Exp Med; 2007 Nov; 204(12):2875-88. PubMed ID: 17984302
[TBL] [Abstract][Full Text] [Related]
14. Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas.
Jen KY; Song IY; Banta KL; Wu D; Mao JH; Balmain A
Blood; 2012 Jan; 119(3):805-9. PubMed ID: 22117044
[TBL] [Abstract][Full Text] [Related]
15. Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation.
Fujii Y; Yada M; Nishiyama M; Kamura T; Takahashi H; Tsunematsu R; Susaki E; Nakagawa T; Matsumoto A; Nakayama KI
Cancer Sci; 2006 Aug; 97(8):729-36. PubMed ID: 16863506
[TBL] [Abstract][Full Text] [Related]
16. Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc.
Kim HS; Woolard K; Lai C; Bauer PO; Maric D; Song H; Li A; Kotliarova S; Zhang W; Fine HA
Cancer Res; 2012 Nov; 72(22):6065-75. PubMed ID: 22986743
[TBL] [Abstract][Full Text] [Related]
17. p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma.
Li Z; Sun Y; Chen X; Squires J; Nowroozizadeh B; Liang C; Huang J
Mol Cancer Res; 2015 Mar; 13(3):584-91. PubMed ID: 25512615
[TBL] [Abstract][Full Text] [Related]
18. RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses.
Dolly SO; Gurden MD; Drosopoulos K; Clarke P; de Bono J; Kaye S; Workman P; Linardopoulos S
Br J Cancer; 2017 Sep; 117(7):954-964. PubMed ID: 28829765
[TBL] [Abstract][Full Text] [Related]
19. The FBXW7 beta-form is suppressed in human glioma cells.
Gu Z; Inomata K; Ishizawa K; Horii A
Biochem Biophys Res Commun; 2007 Mar; 354(4):992-8. PubMed ID: 17274947
[TBL] [Abstract][Full Text] [Related]
20. The tumor suppressor gene FBXW7 is disrupted by a constitutional t(3;4)(q21;q31) in a patient with renal cell cancer.
Kuiper RP; Vreede L; Venkatachalam R; Ricketts C; Kamping E; Verwiel E; Govaerts L; Debiec-Rychter M; Lerut E; van Erp F; Hoogerbrugge N; van Kempen L; Schoenmakers EF; Bonne A; Maher ER; Geurts van Kessel A
Cancer Genet Cytogenet; 2009 Dec; 195(2):105-11. PubMed ID: 19963109
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]