These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1630 related articles for article (PubMed ID: 15593186)

  • 1. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
    Mori Y; Ishida W; Bhattacharyya S; Li Y; Platanias LC; Varga J
    Arthritis Rheum; 2004 Dec; 50(12):4008-21. PubMed ID: 15593186
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
    Ghosh AK; Bhattacharyya S; Lakos G; Chen SJ; Mori Y; Varga J
    Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S; Ghosh AK; Pannu J; Mori Y; Takagawa S; Chen G; Trojanowska M; Gilliam AC; Varga J
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts.
    Mori Y; Chen SJ; Varga J
    Arthritis Rheum; 2003 Jul; 48(7):1964-78. PubMed ID: 12847691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.
    DaCosta Byfield S; Major C; Laping NJ; Roberts AB
    Mol Pharmacol; 2004 Mar; 65(3):744-52. PubMed ID: 14978253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
    Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR.
    Osman B; Doller A; Akool el-S; Holdener M; Hintermann E; Pfeilschifter J; Eberhardt W
    Cell Signal; 2009 Dec; 21(12):1806-17. PubMed ID: 19666112
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J; Gardner H; Shearstone JR; Smith E; Trojanowska M
    Arthritis Rheum; 2006 Sep; 54(9):3011-21. PubMed ID: 16947635
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma.
    Pannu J; Gore-Hyer E; Yamanaka M; Smith EA; Rubinchik S; Dong JY; Jablonska S; Blaszczyk M; Trojanowska M
    Arthritis Rheum; 2004 May; 50(5):1566-77. PubMed ID: 15146427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.
    Goumans MJ; Mummery C
    Int J Dev Biol; 2000 Apr; 44(3):253-65. PubMed ID: 10853822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.
    Hasegawa M; Matsushita Y; Horikawa M; Higashi K; Tomigahara Y; Kaneko H; Shirasaki F; Fujimoto M; Takehara K; Sato S
    Arthritis Rheum; 2009 Nov; 60(11):3465-75. PubMed ID: 19877032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of the activin A-ALK-Smad pathway in systemic sclerosis.
    Takagi K; Kawaguchi Y; Kawamoto M; Ota Y; Tochimoto A; Gono T; Katsumata Y; Takagi M; Hara M; Yamanaka H
    J Autoimmun; 2011 May; 36(3-4):181-8. PubMed ID: 21377836
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts.
    Liu X; Sun SQ; Hassid A; Ostrom RS
    Mol Pharmacol; 2006 Dec; 70(6):1992-2003. PubMed ID: 16959941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors.
    Ihn H; Yamane K; Kubo M; Tamaki K
    Arthritis Rheum; 2001 Feb; 44(2):474-80. PubMed ID: 11229480
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective inhibitors of type I receptor kinase block cellular transforming growth factor-beta signaling.
    Ge R; Rajeev V; Subramanian G; Reiss KA; Liu D; Higgins L; Joly A; Dugar S; Chakravarty J; Henson M; McEnroe G; Schreiner G; Reiss M
    Biochem Pharmacol; 2004 Jul; 68(1):41-50. PubMed ID: 15183116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts.
    Chen Y; Shi-wen X; Eastwood M; Black CM; Denton CP; Leask A; Abraham DJ
    Arthritis Rheum; 2006 Apr; 54(4):1309-16. PubMed ID: 16575856
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells.
    Yang L; Yang J; Venkateswarlu S; Ko T; Brattain MG
    J Cell Physiol; 2001 Sep; 188(3):383-93. PubMed ID: 11473365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts.
    Zhang GY; Li X; Yi CG; Pan H; He GD; Yu Q; Jiang LF; Xu WH; Li ZJ; Ding J; Lin DS; Gao WY
    Exp Dermatol; 2009 Nov; 18(11):947-53. PubMed ID: 19397700
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
    Meyer-ter-Vehn T; Sieprath S; Katzenberger B; Gebhardt S; Grehn F; Schlunck G
    Invest Ophthalmol Vis Sci; 2006 Nov; 47(11):4895-904. PubMed ID: 17065504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition.
    Yang J; Dai C; Liu Y
    J Am Soc Nephrol; 2005 Jan; 16(1):68-78. PubMed ID: 15537870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 82.