These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
25. Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. Laggner C; Schieferer C; Fiechtner B; Poles G; Hoffmann RD; Glossmann H; Langer T; Moebius FF J Med Chem; 2005 Jul; 48(15):4754-64. PubMed ID: 16033255 [TBL] [Abstract][Full Text] [Related]
26. Synthesis, structure and quantitative structure-activity relationships of sigma receptor ligands, 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl) piperazines. Fujimura K; Matsumoto J; Niwa M; Kobayashi T; Kawashima Y; In Y; Ishida T Bioorg Med Chem; 1997 Aug; 5(8):1675-83. PubMed ID: 9313869 [TBL] [Abstract][Full Text] [Related]
27. Functional assays to define agonists and antagonists of the sigma-2 receptor. Zeng C; Rothfuss JM; Zhang J; Vangveravong S; Chu W; Li S; Tu Z; Xu J; Mach RH Anal Biochem; 2014 Mar; 448():68-74. PubMed ID: 24333652 [TBL] [Abstract][Full Text] [Related]
28. 3D-chiral quadratic indices of the 'molecular pseudograph's atom adjacency matrix' and their application to central chirality codification: classification of ACE inhibitors and prediction of sigma-receptor antagonist activities. Ponce YM; Diaz HG; Zaldivar VR; Torrens F; Castro EA Bioorg Med Chem; 2004 Oct; 12(20):5331-42. PubMed ID: 15388160 [TBL] [Abstract][Full Text] [Related]
29. Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (σ) receptor ligands modulates off-target activity and subtype selectivity. Banister SD; Moussa IA; Jorgensen WT; Chua SW; Kassiou M Bioorg Med Chem Lett; 2011 Jun; 21(12):3622-6. PubMed ID: 21555222 [TBL] [Abstract][Full Text] [Related]
30. The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors. Mach RH; Wu L; West T; Whirrett BR; Childers SR Life Sci; 1999; 64(10):PL131-7. PubMed ID: 10096443 [TBL] [Abstract][Full Text] [Related]
31. Identification of a potent and selective σ₁ receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Rossi D; Pedrali A; Urbano M; Gaggeri R; Serra M; Fernández L; Fernández M; Caballero J; Ronsisvalle S; Prezzavento O; Schepmann D; Wuensch B; Peviani M; Curti D; Azzolina O; Collina S Bioorg Med Chem; 2011 Nov; 19(21):6210-24. PubMed ID: 21967807 [TBL] [Abstract][Full Text] [Related]
33. A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands. Floresta G; Amata E; Barbaraci C; Gentile D; Turnaturi R; Marrazzo A; Rescifina A Mar Drugs; 2018 Oct; 16(10):. PubMed ID: 30322188 [TBL] [Abstract][Full Text] [Related]
34. Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples. McLeod MC; Aubé J; Frankowski KJ Bioorg Med Chem Lett; 2016 Dec; 26(23):5689-5694. PubMed ID: 27839919 [TBL] [Abstract][Full Text] [Related]
35. Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor. Kedjouar B; Daunes S; Vilner BJ; Bowen WD; Klaebe A; Faye JC; Poirot M Biochem Pharmacol; 1999 Dec; 58(12):1927-39. PubMed ID: 10591147 [TBL] [Abstract][Full Text] [Related]
36. A systematic exploration of the effects of flexibility and basicity on sigma (σ) receptor binding in a series of substituted diamines. Conroy T; Manohar M; Gong Y; Wilkinson SM; Webster M; Lieberman BP; Banister SD; Reekie TA; Mach RH; Rendina LM; Kassiou M Org Biomol Chem; 2016 Oct; 14(39):9388-9405. PubMed ID: 27714195 [TBL] [Abstract][Full Text] [Related]
37. Synthesis and evaluation of tetrahydroindazole derivatives as sigma-2 receptor ligands. Wu ZW; Song SY; Li L; Lu HL; Lieberman B; Huang YS; Mach RH Bioorg Med Chem; 2015 Apr; 23(7):1463-71. PubMed ID: 25752422 [TBL] [Abstract][Full Text] [Related]
38. Pharmacophore models and development of spirocyclic ligands for σ1 receptors. Wunsch B Curr Pharm Des; 2012; 18(7):930-7. PubMed ID: 22288413 [TBL] [Abstract][Full Text] [Related]
39. Design and Investigation of a [ Yang D; Comeau A; Bowen WD; Mach RH; Ross BD; Hong H; Van Dort ME Mol Pharm; 2017 Mar; 14(3):770-780. PubMed ID: 28135101 [TBL] [Abstract][Full Text] [Related]