154 related articles for article (PubMed ID: 15598073)
1. Synthesis, 18F-radiolabelling and biological evaluations of C-6 alkylated pyrimidine nucleoside analogues.
Raić-Malić S; Johayem A; Ametamey SM; Batinac S; De Clercq E; Folkers G; Scapozza L
Nucleosides Nucleotides Nucleic Acids; 2004; 23(11):1707-21. PubMed ID: 15598073
[TBL] [Abstract][Full Text] [Related]
2. Fluorosubstitution and 7-alkylation as prospective modifications of biologically active 6-aryl derivatives of tricyclic acyclovir and ganciclovir analogues.
Ostrowski T; Golankiewicz B; De Clercq E; Balzarini J
Bioorg Med Chem; 2005 Mar; 13(6):2089-96. PubMed ID: 15727862
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Russ P; Schelling P; Scapozza L; Folkers G; Clercq ED; Marquez VE
J Med Chem; 2003 Nov; 46(23):5045-54. PubMed ID: 14584954
[TBL] [Abstract][Full Text] [Related]
4. Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
Degrève B; Esnouf R; De Clercq E; Balzarini J
Mol Pharmacol; 2000 Dec; 58(6):1326-32. PubMed ID: 11093770
[TBL] [Abstract][Full Text] [Related]
5. The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.
Balzarini J; Liekens S; Esnouf R; De Clercq E
Biochemistry; 2002 May; 41(20):6517-24. PubMed ID: 12009916
[TBL] [Abstract][Full Text] [Related]
6. Comparison of HSV-1 thymidine kinase-dependent and -independent inhibition of replication-competent adenoviral vectors by a panel of drugs.
Wildner O; Hoffmann D; Jogler C; Uberla K
Cancer Gene Ther; 2003 Oct; 10(10):791-802. PubMed ID: 14502232
[TBL] [Abstract][Full Text] [Related]
7. Potentiation of ganciclovir toxicity in the herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin.
Hayashi K; Hayashi T; Sun HD; Takeda Y
Cancer Gene Ther; 2000 Jan; 7(1):45-52. PubMed ID: 10678355
[TBL] [Abstract][Full Text] [Related]
8. Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
Wang HE; Yu HM; Liu RS; Lin M; Gelovani JG; Hwang JJ; Wei HJ; Deng WP
J Nucl Med; 2006 Jul; 47(7):1161-71. PubMed ID: 16818951
[TBL] [Abstract][Full Text] [Related]
9. Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells.
Balzarini J; Degrève B; Andrei G; Neyts J; Sandvold M; Myhren F; de Clercq E
Gene Ther; 1998 Mar; 5(3):419-26. PubMed ID: 9614564
[TBL] [Abstract][Full Text] [Related]
10. Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations.
Benci K; Suhina T; Mandić L; Pavelić SK; Paravić AT; Pavelić K; Balzarini J; Wittine K; Mintas M
Antivir Chem Chemother; 2011 Jul; 21(6):221-30. PubMed ID: 21730369
[TBL] [Abstract][Full Text] [Related]
11. Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1.
Bae PK; Kim JH; Kim HS; Chung IK; Paik SG; Lee CK
Antiviral Res; 2006 Jul; 70(3):93-104. PubMed ID: 16546268
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and ++thiosangivamycin: influence of various 7-substituents on antiviral activity.
Renau TE; Wotring LL; Drach JC; Townsend LB
J Med Chem; 1996 Feb; 39(4):873-80. PubMed ID: 8632411
[TBL] [Abstract][Full Text] [Related]
13. Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir.
Howard BD; Boenicke L; Schniewind B; Henne-Bruns D; Kalthoff H
Cancer Gene Ther; 2000 Jun; 7(6):927-38. PubMed ID: 10880025
[TBL] [Abstract][Full Text] [Related]
14. Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation.
Balzarini J; Liekens S; Solaroli N; El Omari K; Stammers DK; Karlsson A
J Biol Chem; 2006 Jul; 281(28):19273-9. PubMed ID: 16702226
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and evaluation of [18F] labeled pyrimidine nucleosides for positron emission tomography imaging of herpes simplex virus 1 thymidine kinase gene expression.
Pillarsetty N; Cai S; Ageyeva L; Finn RD; Blasberg RG
J Med Chem; 2006 Aug; 49(17):5377-81. PubMed ID: 16913728
[TBL] [Abstract][Full Text] [Related]
16. The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy.
Hayashi K; Lee JB; Maitani Y; Toyooka N; Nemoto H; Hayashi T
J Gene Med; 2006 Aug; 8(8):1056-67. PubMed ID: 16779868
[TBL] [Abstract][Full Text] [Related]
17. C-5 hydroxyethyl and hydroxypropyl acyclonucleosides as substrates for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK): syntheses and biological evaluation.
Meščić A; Krištafor S; Novaković I; Osmanović A; Müller U; Završnik D; Ametamey SM; Scapozza L; Raić-Malić S
Molecules; 2013 May; 18(5):5104-24. PubMed ID: 23644977
[TBL] [Abstract][Full Text] [Related]
18. N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
Hernandez AI; Familiar O; Negri A; Rodríguez-Barrios F; Gago F; Karlsson A; Camarasa MJ; Balzarini J; Pérez-Pérez MJ
J Med Chem; 2006 Dec; 49(26):7766-73. PubMed ID: 17181158
[TBL] [Abstract][Full Text] [Related]
19. Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells.
Burrows FJ; Gore M; Smiley WR; Kanemitsu MY; Jolly DJ; Read SB; Nicholas T; Kruse CA
Cancer Gene Ther; 2002 Jan; 9(1):87-95. PubMed ID: 11916247
[TBL] [Abstract][Full Text] [Related]
20. Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines.
Balzarini J; Ostrowski T; Goslinski T; De Clercq E; Golankiewicz B
Gene Ther; 2002 Sep; 9(17):1173-82. PubMed ID: 12170381
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
