These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 1559990)

  • 21. On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase.
    Kulik V; Weyand M; Seidel R; Niks D; Arac D; Dunn MF; Schlichting I
    J Mol Biol; 2002 Dec; 324(4):677-90. PubMed ID: 12460570
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Importance of conserved and variable C-terminal residues for the activity and thermal stability of the beta subunit of tryptophan synthase.
    Yang L; Ahmed SA; Rhee S; Miles EW
    J Biol Chem; 1997 Mar; 272(12):7859-66. PubMed ID: 9065452
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Affinities of phosphorylated substrates for the E. coli tryptophan synthase alpha-subunit: roles of Ser-235 and helix-8' dipole.
    Sarker KD; Hardman JK
    Proteins; 1995 Feb; 21(2):130-9. PubMed ID: 7777488
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Thermal repair of tryptophan synthase mutations in a regulatory intersubunit salt bridge. Evidence from arrhenius plots, absorption spectra, and primary kinetic isotope effects.
    Fan YX; McPhie P; Miles EW
    J Biol Chem; 2000 Jul; 275(27):20302-7. PubMed ID: 10801803
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Identification of the geometric requirements for allosteric communication between the alpha- and beta-subunits of tryptophan synthase.
    Raboni S; Bettati S; Mozzarelli A
    J Biol Chem; 2005 Apr; 280(14):13450-6. PubMed ID: 15691828
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone.
    Nishio K; Morimoto Y; Ishizuka M; Ogasahara K; Tsukihara T; Yutani K
    Biochemistry; 2005 Feb; 44(4):1184-92. PubMed ID: 15667212
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The tryptophan synthase multienzyme complex: exploring structure-function relationships with X-ray crystallography and mutagenesis.
    Hyde CC; Miles EW
    Biotechnology (N Y); 1990 Jan; 8(1):27-32. PubMed ID: 1366510
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mutations in the contact region between the alpha and beta subunits of tryptophan synthase alter subunit interaction and intersubunit communication.
    Rowlett R; Yang LH; Ahmed SA; McPhie P; Jhee KH; Miles EW
    Biochemistry; 1998 Mar; 37(9):2961-8. PubMed ID: 9485448
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Tryptophan synthase: structure and function of the monovalent cation site.
    Dierkers AT; Niks D; Schlichting I; Dunn MF
    Biochemistry; 2009 Nov; 48(46):10997-1010. PubMed ID: 19848417
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Site-directed mutagenesis of the alpha subunit of tryptophan synthase from Salmonella typhimurium.
    Ahmed SA; Kawasaki H; Bauerle R; Morita H; Miles EW
    Biochem Biophys Res Commun; 1988 Mar; 151(2):672-8. PubMed ID: 3126743
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Origin of the mutual activation of the alpha and beta 2 subunits in the alpha 2 beta 2 complex of tryptophan synthase. Effect of alanine or glycine substitutions at proline residues in the alpha subunit.
    Ogasahara K; Hiraga K; Ito W; Miles EW; Yutani K
    J Biol Chem; 1992 Mar; 267(8):5222-8. PubMed ID: 1544905
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The tryptophan synthase bienzyme complex transfers indole between the alpha- and beta-sites via a 25-30 A long tunnel.
    Dunn MF; Aguilar V; Brzović P; Drewe WF; Houben KF; Leja CA; Roy M
    Biochemistry; 1990 Sep; 29(37):8598-607. PubMed ID: 2271543
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Site-directed mutagenesis of the beta subunit of tryptophan synthase from Salmonella typhimurium. Role of active site glutamic acid 350.
    Kayastha AM; Sawa Y; Nagata S; Miles EW
    J Biol Chem; 1991 Apr; 266(12):7618-25. PubMed ID: 1673461
    [TBL] [Abstract][Full Text] [Related]  

  • 34. pH dependence of tryptophan synthase catalytic mechanism: I. The first stage, the beta-elimination reaction.
    Schiaretti F; Bettati S; Viappiani C; Mozzarelli A
    J Biol Chem; 2004 Jul; 279(28):29572-82. PubMed ID: 15117965
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity.
    Ferrari D; Yang LH; Miles EW; Dunn MF
    Biochemistry; 2001 Jun; 40(25):7421-32. PubMed ID: 11412095
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure and function of the tryptophan synthase alpha(2)beta(2) complex. Roles of beta subunit histidine 86.
    Ro HS; Miles EW
    J Biol Chem; 1999 Dec; 274(51):36439-45. PubMed ID: 10593940
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Tryptophan synthase mutations that alter cofactor chemistry lead to mechanism-based inactivation.
    Jhee KH; McPhie P; Ro HS; Miles EW
    Biochemistry; 1998 Oct; 37(41):14591-604. PubMed ID: 9772188
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structural conservation in parallel beta/alpha-barrel enzymes that catalyze three sequential reactions in the pathway of tryptophan biosynthesis.
    Wilmanns M; Hyde CC; Davies DR; Kirschner K; Jansonius JN
    Biochemistry; 1991 Sep; 30(38):9161-9. PubMed ID: 1892826
    [TBL] [Abstract][Full Text] [Related]  

  • 39. beta-Site covalent reactions trigger transitions between open and closed conformations of the tryptophan synthase bienzyme complex.
    Pan P; Dunn MF
    Biochemistry; 1996 Apr; 35(15):5002-13. PubMed ID: 8664293
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Aliphatic alcohols stabilize an alternative conformation of the tryptophan synthase alpha 2 beta 2 complex from Salmonella typhimurium.
    Ahmed SA; Miles EW
    J Biol Chem; 1994 Jun; 269(23):16486-92. PubMed ID: 8206958
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.