BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 15602006)

  • 21. Differences in the longevity of topo IIalpha and topo IIbeta drug-stabilized cleavable complexes and the relationship to drug sensitivity.
    Errington F; Willmore E; Leontiou C; Tilby MJ; Austin CA
    Cancer Chemother Pharmacol; 2004 Feb; 53(2):155-62. PubMed ID: 14504921
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Lycobetaine acts as a selective topoisomerase II beta poison and inhibits the growth of human tumour cells.
    Barthelmes HU; Niederberger E; Roth T; Schulte K; Tang WC; Boege F; Fiebig HH; Eisenbrand G; Marko D
    Br J Cancer; 2001 Nov; 85(10):1585-91. PubMed ID: 11720449
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Topoisomerase IIalpha mRNA and protein expression vs. in vitro drug resistance and clinical outcome in acute leukaemia.
    Uggla B; Tina E; Nahi H; Paul C; Höglund M; Sirsjö A; Tidefelt U
    Int J Oncol; 2007 Jul; 31(1):153-60. PubMed ID: 17549416
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.
    Huang H; Chen Q; Ku X; Meng L; Lin L; Wang X; Zhu C; Wang Y; Chen Z; Li M; Jiang H; Chen K; Ding J; Liu H
    J Med Chem; 2010 Apr; 53(8):3048-64. PubMed ID: 20353152
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIalpha.
    Jonstrup AT; Thomsen T; Wang Y; Knudsen BR; Koch J; Andersen AH
    Nucleic Acids Res; 2008 Nov; 36(19):6165-74. PubMed ID: 18824478
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NK314, a novel topoisomerase II inhibitor, induces rapid DNA double-strand breaks and exhibits superior antitumor effects against tumors resistant to other topoisomerase II inhibitors.
    Onda T; Toyoda E; Miyazaki O; Seno C; Kagaya S; Okamoto K; Nishikawa K
    Cancer Lett; 2008 Jan; 259(1):99-110. PubMed ID: 17998154
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Regulation of p38 phosphorylation and topoisomerase IIalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.
    Yamochi T; Yamochi T; Aytac U; Sato T; Sato K; Ohnuma K; McKee KS; Morimoto C; Dang NH
    Cancer Res; 2005 Mar; 65(5):1973-83. PubMed ID: 15753397
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mechanism of action of ferrocene derivatives on the catalytic activity of topoisomerase IIalpha and beta--distinct mode of action of two derivatives.
    Sai Krishna AD; Panda G; Kondapi AK
    Arch Biochem Biophys; 2005 Jun; 438(2):206-16. PubMed ID: 15907782
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells.
    Christensen MO; Larsen MK; Barthelmes HU; Hock R; Andersen CL; Kjeldsen E; Knudsen BR; Westergaard O; Boege F; Mielke C
    J Cell Biol; 2002 Apr; 157(1):31-44. PubMed ID: 11927602
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The ATP-operated clamp of human DNA topoisomerase IIalpha: hyperstimulation of ATPase by "piggy-back" binding.
    Campbell S; Maxwell A
    J Mol Biol; 2002 Jul; 320(2):171-88. PubMed ID: 12079377
    [TBL] [Abstract][Full Text] [Related]  

  • 32. High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay.
    Singh PK; Chan PF; Hibbs MJ; Vazquez MJ; Segura DC; Thomas DA; Theobald AJ; Gallagher KT; Hassan NJ
    Protein Expr Purif; 2011 Apr; 76(2):165-72. PubMed ID: 20709174
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Functional compatibility between isoform alpha and beta of type II DNA topoisomerase.
    Sakaguchi A; Kikuchi A
    J Cell Sci; 2004 Mar; 117(Pt 7):1047-54. PubMed ID: 14996935
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.
    Leontiou C; Lakey JH; Austin CA
    Mol Pharmacol; 2004 Sep; 66(3):430-9. PubMed ID: 15322234
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo.
    Grauslund M; Thougaard AV; Füchtbauer A; Hofland KF; Hjorth PH; Jensen PB; Sehested M; Füchtbauer EM; Jensen LH
    Mol Pharmacol; 2007 Oct; 72(4):1003-14. PubMed ID: 17622580
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The QTK loop is essential for the communication between the N-terminal atpase domain and the central cleavage--ligation region in human topoisomerase IIalpha.
    Bendsen S; Oestergaard VH; Skouboe C; Brinch M; Knudsen BR; Andersen AH
    Biochemistry; 2009 Jul; 48(27):6508-15. PubMed ID: 19485418
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Topoisomerase II beta levels are a determinant of melphalan-induced DNA crosslinks and sensitivity to cell death.
    Emmons M; Boulware D; Sullivan DM; Hazlehurst LA
    Biochem Pharmacol; 2006 Jun; 72(1):11-8. PubMed ID: 16678798
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Transcriptional regulation of the human topoisomerase IIalpha gene.
    Bronner C; Hopfner R; Mousli M
    Anticancer Res; 2002; 22(2A):605-12. PubMed ID: 12014628
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Self-association and DNA binding properties of the human topoisomerase IIA alpha2HTH module.
    Morant-Lhomel A; René B; Zargarian L; Troalen F; Mauffret O; Fermandjian S
    Biochimie; 2006; 88(3-4):253-63. PubMed ID: 16213649
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Quantitative analysis of topoisomerase IIalpha to rapidly evaluate cell proliferation in brain tumors.
    Oda M; Arakawa Y; Kano H; Kawabata Y; Katsuki T; Shirahata M; Ono M; Yamana N; Hashimoto N; Takahashi JA
    Biochem Biophys Res Commun; 2005 Jun; 331(4):971-6. PubMed ID: 15882973
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.