BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 15605246)

  • 1. Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity.
    Nielsen K; Kruhøffer M; Orntoft T; Sparre T; Wang H; Wollheim C; Jørgensen MC; Nerup J; Karlsen AE
    Diabetologia; 2004 Dec; 47(12):2185-99. PubMed ID: 15605246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beta-cell maturation leads to in vitro sensitivity to cytotoxins.
    Nielsen K; Karlsen AE; Deckert M; Madsen OD; Serup P; Mandrup-Poulsen T; Nerup J
    Diabetes; 1999 Dec; 48(12):2324-32. PubMed ID: 10580420
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein expression changes in a cell system of beta-cell maturation reflect an acquired sensitivity to IL-1beta.
    Nielsen K; Sparre T; Larsen MR; Nielsen M; Fey SJ; Mose Larsen P; Roepstorff P; Nerup J; Karlsen AE
    Diabetologia; 2004 Jan; 47(1):62-74. PubMed ID: 14652719
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.
    Schisler JC; Jensen PB; Taylor DG; Becker TC; Knop FK; Takekawa S; German M; Weir GC; Lu D; Mirmira RG; Newgard CB
    Proc Natl Acad Sci U S A; 2005 May; 102(20):7297-302. PubMed ID: 15883383
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PDX-1 induces differentiation of intestinal epithelioid IEC-6 into insulin-producing cells.
    Yoshida S; Kajimoto Y; Yasuda T; Watada H; Fujitani Y; Kosaka H; Gotow T; Miyatsuka T; Umayahara Y; Yamasaki Y; Hori M
    Diabetes; 2002 Aug; 51(8):2505-13. PubMed ID: 12145164
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
    Hayes HL; Moss LG; Schisler JC; Haldeman JM; Zhang Z; Rosenberg PB; Newgard CB; Hohmeier HE
    Mol Cell Biol; 2013 Oct; 33(20):4017-29. PubMed ID: 23938296
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.
    Karlsen AE; Rønn SG; Lindberg K; Johannesen J; Galsgaard ED; Pociot F; Nielsen JH; Mandrup-Poulsen T; Nerup J; Billestrup N
    Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12191-6. PubMed ID: 11593036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.
    Pavlovic D; Chen MC; Gysemans CA; Mathieu C; Eizirik DL
    Eur Cytokine Netw; 1999 Sep; 10(3):403-12. PubMed ID: 10477397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.
    Wang H; Iezzi M; Theander S; Antinozzi PA; Gauthier BR; Halban PA; Wollheim CB
    Diabetologia; 2005 Apr; 48(4):720-31. PubMed ID: 15756539
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.
    Cardozo AK; Kruhøffer M; Leeman R; Orntoft T; Eizirik DL
    Diabetes; 2001 May; 50(5):909-20. PubMed ID: 11334433
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytokines affect PDX-1 expression, insulin and proinsulin secretion from iNOS deficient murine islets.
    Andersson AK; Börjesson A; Sandgren J; Sandler S
    Mol Cell Endocrinol; 2005 Aug; 240(1-2):50-7. PubMed ID: 16023781
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The C-terminal domain of the beta cell homeodomain factor Nkx6.1 enhances sequence-selective DNA binding at the insulin promoter.
    Taylor DG; Babu D; Mirmira RG
    Biochemistry; 2005 Aug; 44(33):11269-78. PubMed ID: 16101311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
    Ling Z; Van de Casteele M; Eizirik DL; Pipeleers DG
    Diabetes; 2000 Mar; 49(3):340-5. PubMed ID: 10868954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peroxisome proliferator-activated receptor-gamma regulates expression of PDX-1 and NKX6.1 in INS-1 cells.
    Moibi JA; Gupta D; Jetton TL; Peshavaria M; Desai R; Leahy JL
    Diabetes; 2007 Jan; 56(1):88-95. PubMed ID: 17192469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.
    Hong TP; Andersen NA; Nielsen K; Karlsen AE; Fantuzzi G; Eizirik DL; Dinarello CA; Mandrup-Poulsen T
    Eur Cytokine Netw; 2000 Jun; 11(2):193-205. PubMed ID: 10903798
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NKX6.1 promotes PDX-1-induced liver to pancreatic β-cells reprogramming.
    Gefen-Halevi S; Rachmut IH; Molakandov K; Berneman D; Mor E; Meivar-Levy I; Ferber S
    Cell Reprogram; 2010 Dec; 12(6):655-64. PubMed ID: 21108535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peroxisome proliferator-activated receptor-alpha regulates the expression of pancreatic/duodenal homeobox-1 in rat insulinoma (INS-1) cells and ameliorates glucose-induced insulin secretion impaired by palmitate.
    Sun Y; Zhang L; Gu HF; Han W; Ren M; Wang F; Gong B; Wang L; Guo H; Xin W; Zhao J; Gao L
    Endocrinology; 2008 Feb; 149(2):662-71. PubMed ID: 17991720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.
    Ammendrup A; Maillard A; Nielsen K; Aabenhus Andersen N; Serup P; Dragsbaek Madsen O; Mandrup-Poulsen T; Bonny C
    Diabetes; 2000 Sep; 49(9):1468-76. PubMed ID: 10969830
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells.
    Lottmann H; Vanselow J; Hessabi B; Walther R
    J Mol Med (Berl); 2001 Jun; 79(5-6):321-8. PubMed ID: 11485027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDX-1 expression is associated with islet proliferation in vitro and in vivo.
    Feanny MA; Fagan SP; Ballian N; Liu SH; Li Z; Wang X; Fisher W; Brunicardi FC; Belaguli NS
    J Surg Res; 2008 Jan; 144(1):8-16. PubMed ID: 17583748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.