316 related articles for article (PubMed ID: 15605273)
1. Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells.
Lee SH; McCormick F
J Mol Med (Berl); 2005 Apr; 83(4):296-307. PubMed ID: 15605273
[TBL] [Abstract][Full Text] [Related]
2. p27(Kip1) stabilization and G(1) arrest by 1,25-dihydroxyvitamin D(3) in ovarian cancer cells mediated through down-regulation of cyclin E/cyclin-dependent kinase 2 and Skp1-Cullin-F-box protein/Skp2 ubiquitin ligase.
Li P; Li C; Zhao X; Zhang X; Nicosia SV; Bai W
J Biol Chem; 2004 Jun; 279(24):25260-7. PubMed ID: 15075339
[TBL] [Abstract][Full Text] [Related]
3. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
[TBL] [Abstract][Full Text] [Related]
4. Skp2 directs Myc-mediated suppression of p27Kip1 yet has modest effects on Myc-driven lymphomagenesis.
Old JB; Kratzat S; Hoellein A; Graf S; Nilsson JA; Nilsson L; Nakayama KI; Peschel C; Cleveland JL; Keller UB
Mol Cancer Res; 2010 Mar; 8(3):353-62. PubMed ID: 20197382
[TBL] [Abstract][Full Text] [Related]
5. Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter H; Friedrich M; Resch A; Kullmann M; Stögbauer F; Ringelstein EB; Hengst L
Cancer Res; 2006 Jul; 66(13):6530-9. PubMed ID: 16818624
[TBL] [Abstract][Full Text] [Related]
6. Vorinostat enhances protein stability of p27 and p21 through negative regulation of Skp2 and Cks1 in human breast cancer cells.
Uehara N; Yoshizawa K; Tsubura A
Oncol Rep; 2012 Jul; 28(1):105-10. PubMed ID: 22484732
[TBL] [Abstract][Full Text] [Related]
7. PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27(KIP1) through the ubiquitin E3 ligase SCF(SKP2).
Mamillapalli R; Gavrilova N; Mihaylova VT; Tsvetkov LM; Wu H; Zhang H; Sun H
Curr Biol; 2001 Feb; 11(4):263-7. PubMed ID: 11250155
[TBL] [Abstract][Full Text] [Related]
8. Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication.
Nakayama K; Nagahama H; Minamishima YA; Matsumoto M; Nakamichi I; Kitagawa K; Shirane M; Tsunematsu R; Tsukiyama T; Ishida N; Kitagawa M; Nakayama K; Hatakeyama S
EMBO J; 2000 May; 19(9):2069-81. PubMed ID: 10790373
[TBL] [Abstract][Full Text] [Related]
9. BCR-ABL induces the expression of Skp2 through the PI3K pathway to promote p27Kip1 degradation and proliferation of chronic myelogenous leukemia cells.
Andreu EJ; Lledó E; Poch E; Ivorra C; Albero MP; Martínez-Climent JA; Montiel-Duarte C; Rifón J; Pérez-Calvo J; Arbona C; Prósper F; Pérez-Roger I
Cancer Res; 2005 Apr; 65(8):3264-72. PubMed ID: 15833859
[TBL] [Abstract][Full Text] [Related]
10. CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.
Appleman LJ; Chernova I; Li L; Boussiotis VA
Cell Cycle; 2006 Sep; 5(18):2123-9. PubMed ID: 16969077
[TBL] [Abstract][Full Text] [Related]
11. Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.
Ungermannova D; Gao Y; Liu X
J Biol Chem; 2005 Aug; 280(34):30301-9. PubMed ID: 15980415
[TBL] [Abstract][Full Text] [Related]
12. Antimitogenesis linked to regulation of Skp2 gene expression.
Stewart SA; Kothapalli D; Yung Y; Assoian RK
J Biol Chem; 2004 Jul; 279(28):29109-13. PubMed ID: 15126498
[TBL] [Abstract][Full Text] [Related]
13. Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarcomas.
Huang HY; Kang HY; Li CF; Eng HL; Chou SC; Lin CN; Hsiung CY
Clin Cancer Res; 2006 Jan; 12(2):487-98. PubMed ID: 16428491
[TBL] [Abstract][Full Text] [Related]
14. Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase.
Bashir T; Dorrello NV; Amador V; Guardavaccaro D; Pagano M
Nature; 2004 Mar; 428(6979):190-3. PubMed ID: 15014502
[TBL] [Abstract][Full Text] [Related]
15. p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 function.
Liu S; Yamauchi H
Cancer Lett; 2009 Dec; 286(2):240-9. PubMed ID: 19631451
[TBL] [Abstract][Full Text] [Related]
16. Downregulation of Skp2 inhibits the growth and metastasis of gastric cancer cells in vitro and in vivo.
Wei Z; Jiang X; Liu F; Qiao H; Zhou B; Zhai B; Zhang L; Zhang X; Han L; Jiang H; Krissansen GW; Sun X
Tumour Biol; 2013 Feb; 34(1):181-92. PubMed ID: 23229098
[TBL] [Abstract][Full Text] [Related]
17. Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells.
Westbrook L; Manuvakhova M; Kern FG; Estes NR; Ramanathan HN; Thottassery JV
Cancer Res; 2007 Dec; 67(23):11393-401. PubMed ID: 18056467
[TBL] [Abstract][Full Text] [Related]
18. SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
Calvisi DF; Ladu S; Pinna F; Frau M; Tomasi ML; Sini M; Simile MM; Bonelli P; Muroni MR; Seddaiu MA; Lim DS; Feo F; Pascale RM
Gastroenterology; 2009 Nov; 137(5):1816-26.e1-10. PubMed ID: 19686743
[TBL] [Abstract][Full Text] [Related]
19. Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase.
Xu S; Abbasian M; Patel P; Jensen-Pergakes K; Lombardo CR; Cathers BE; Xie W; Mercurio F; Pagano M; Giegel D; Cox S
J Biol Chem; 2007 May; 282(21):15462-70. PubMed ID: 17409098
[TBL] [Abstract][Full Text] [Related]
20. Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4. Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation.
Tamamori-Adachi M; Hayashida K; Nobori K; Omizu C; Yamada K; Sakamoto N; Kamura T; Fukuda K; Ogawa S; Nakayama KI; Kitajima S
J Biol Chem; 2004 Nov; 279(48):50429-36. PubMed ID: 15371458
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]