BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 15606134)

  • 1. Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene.
    El-Bayoumy K; Sharma AK; Lin JM; Krzeminski J; Boyiri T; King LC; Lambert G; Padgett W; Nesnow S; Amin S
    Chem Res Toxicol; 2004 Dec; 17(12):1591-9. PubMed ID: 15606134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene.
    Krzeminski J; Kropachev K; Kolbanovskiy M; Reeves D; Kolbanovskiy A; Yun BH; Geacintov NE; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2011 Jan; 24(1):65-72. PubMed ID: 21114286
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts.
    Krzeminski J; Kropachev K; Reeves D; Kolbanovskiy A; Kolbanovskiy M; Chen KM; Sharma AK; Geacintov N; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2013 Nov; 26(11):1746-54. PubMed ID: 24112095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland.
    El-Bayoumy K; Desai D; Boyiri T; Rosa J; Krzeminski J; Sharma AK; Pittman B; Amin S
    Chem Res Toxicol; 2002 Jul; 15(7):972-8. PubMed ID: 12119009
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts in isolated rat hepatocytes treated with 6-nitrochrysene and 6-aminochrysene.
    Delclos KB; Miller DW; Lay JO; Casciano DA; Walker RP; Fu PP; Kadlubar FF
    Carcinogenesis; 1987 Nov; 8(11):1703-9. PubMed ID: 3664962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism and DNA binding of the environmental colon carcinogen 6-nitrochrysene in rats.
    Chae YH; Delclos KB; Blaydes B; el-Bayoumy K
    Cancer Res; 1996 May; 56(9):2052-8. PubMed ID: 8616850
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism and DNA binding of the environmental pollutant 6-nitrochrysene in primary culture of human breast cells and in cultured MCF-10A, MCF-7 and MDA-MB-435s cell lines.
    Boyiri T; Leszczynska J; Desai D; Amin S; Nixon DW; El-Bayoumy K
    Int J Cancer; 2002 Aug; 100(4):395-400. PubMed ID: 12115519
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line.
    Sun YW; Guttenplan JB; Khmelnitsky M; Krzeminski J; Boyiri T; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2009 Dec; 22(12):1992-7. PubMed ID: 19886636
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat.
    Sun YW; Guttenplan JB; Cooper T; Krzeminski J; Aliaga C; Boyiri T; Kosinska W; Zhao ZL; Chen KM; Berg A; Amin S; El-Bayoumy K
    Chem Res Toxicol; 2013 Apr; 26(4):547-54. PubMed ID: 23461617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line.
    Guttenplan JB; Zhao ZL; Kosinska W; Norman RG; Krzeminski J; Sun YW; Amin S; El-Bayoumy K
    Carcinogenesis; 2007 Nov; 28(11):2391-7. PubMed ID: 17602172
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium.
    el-Bayoumy K; Delclos KB; Heflich RH; Walker R; Shiue GH; Hecht SS
    Mutagenesis; 1989 May; 4(3):235-40. PubMed ID: 2659942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice.
    Li EE; Heflich RH; Bucci TJ; Manjanatha MG; Blaydes BS; Delclos KB
    Carcinogenesis; 1994 Jul; 15(7):1377-85. PubMed ID: 8033314
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic activation of 6-nitrochrysene in explants of human bronchus and in isolated rat hepatocytes.
    Delclos KB; el-Bayoumy K; Casciano DA; Walker RP; Kadlubar FF; Hecht SS; Shivapurkar N; Mandal S; Stoner GD
    Cancer Res; 1989 Jun; 49(11):2909-13. PubMed ID: 2720650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nitroreduction of 4-nitropyrene is primarily responsible for DNA adduct formation in the mammary gland of female CD rats.
    Chae YH; Ji BY; Lin JM; Fu PP; Cho BP; El-Bayoumy K
    Chem Res Toxicol; 1999 Feb; 12(2):180-6. PubMed ID: 10027796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Site-Specific Incorporation of
    Pande P; Rebello KR; Chatterjee A; Naldiga S; Basu AK
    Chem Res Toxicol; 2020 Jul; 33(7):1997-2005. PubMed ID: 32551527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
    Chae YH; Yun CH; Guengerich FP; Kadlubar FF; el-Bayoumy K
    Cancer Res; 1993 May; 53(9):2028-34. PubMed ID: 8481905
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Products formed from the in vitro reaction of metabolites of 3-aminochrysene with calf thymus DNA.
    Herreno-Saenz D; Evans FE; Lai CC; Abian J; Fu PP; Delclos KB
    Chem Biol Interact; 1993 Jan; 86(1):1-15. PubMed ID: 8431961
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene.
    Delclos KB; Walker RP; Dooley KL; Fu PP; Kadlubar FF
    Cancer Res; 1987 Dec; 47(23):6272-7. PubMed ID: 3677076
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene is metabolized to form a major adduct with deoxyguanosine and produces mutations in the hprt gene of Chinese hamster ovary cells at G:C basepairs.
    Li EE; Heflich RH; Delclos KB
    Carcinogenesis; 1993 Oct; 14(10):2109-14. PubMed ID: 8222062
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA adducts from nitroreduction of 2,7-dinitrofluorene, a mammary gland carcinogen, catalyzed by rat liver or mammary gland cytosol.
    Ritter CL; Culp SJ; Freeman JP; Marques MM; Beland FA; Malejka-Giganti D
    Chem Res Toxicol; 2002 Apr; 15(4):536-44. PubMed ID: 11952340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.