138 related articles for article (PubMed ID: 15610006)
1. Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Wan Z; Xu B; Huang K; Chu YC; Li B; Nakagawa SH; Qu Y; Hu SQ; Katsoyannis PG; Weiss MA
Biochemistry; 2004 Dec; 43(51):16119-33. PubMed ID: 15610006
[TBL] [Abstract][Full Text] [Related]
2. Diabetes-associated mutations in human insulin: crystal structure and photo-cross-linking studies of a-chain variant insulin Wakayama.
Wan ZL; Huang K; Xu B; Hu SQ; Wang S; Chu YC; Katsoyannis PG; Weiss MA
Biochemistry; 2005 Apr; 44(13):5000-16. PubMed ID: 15794638
[TBL] [Abstract][Full Text] [Related]
3. Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
Weiss MA; Wan Z; Zhao M; Chu YC; Nakagawa SH; Burke GT; Jia W; Hellmich R; Katsoyannis PG
J Mol Biol; 2002 Jan; 315(2):103-11. PubMed ID: 11779231
[TBL] [Abstract][Full Text] [Related]
4. How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor.
Huang K; Xu B; Hu SQ; Chu YC; Hua QX; Qu Y; Li B; Wang S; Wang RY; Nakagawa SH; Theede AM; Whittaker J; De Meyts P; Katsoyannis PG; Weiss MA
J Mol Biol; 2004 Aug; 341(2):529-50. PubMed ID: 15276842
[TBL] [Abstract][Full Text] [Related]
5. Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor.
Xu B; Hu SQ; Chu YC; Huang K; Nakagawa SH; Whittaker J; Katsoyannis PG; Weiss MA
Biochemistry; 2004 Jul; 43(26):8356-72. PubMed ID: 15222748
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of allo-Ile(A2)-insulin, an inactive chiral analogue: implications for the mechanism of receptor binding.
Wan ZL; Xu B; Chu YC; Katsoyannis PG; Weiss MA
Biochemistry; 2003 Nov; 42(44):12770-83. PubMed ID: 14596591
[TBL] [Abstract][Full Text] [Related]
7. Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures.
Hua QX; Hu SQ; Jia W; Chu YC; Burke GT; Wang SH; Wang RY; Katsoyannis PG; Weiss MA
J Mol Biol; 1998 Mar; 277(1):103-18. PubMed ID: 9514738
[TBL] [Abstract][Full Text] [Related]
8. Receptor binding redefined by a structural switch in a mutant human insulin.
Hua QX; Shoelson SE; Kochoyan M; Weiss MA
Nature; 1991 Nov; 354(6350):238-41. PubMed ID: 1961250
[TBL] [Abstract][Full Text] [Related]
9. Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.
Glendorf T; Sørensen AR; Nishimura E; Pettersson I; Kjeldsen T
Biochemistry; 2008 Apr; 47(16):4743-51. PubMed ID: 18376848
[TBL] [Abstract][Full Text] [Related]
10. Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue.
Xu B; Hua QX; Nakagawa SH; Jia W; Chu YC; Katsoyannis PG; Weiss MA
J Mol Biol; 2002 Feb; 316(3):435-41. PubMed ID: 11866509
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure and site 1 binding energetics of human placental lactogen.
Walsh ST; Kossiakoff AA
J Mol Biol; 2006 May; 358(3):773-84. PubMed ID: 16546209
[TBL] [Abstract][Full Text] [Related]
12. Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue.
Hua QX; Hu SQ; Frank BH; Jia W; Chu YC; Wang SH; Burke GT; Katsoyannis PG; Weiss MA
J Mol Biol; 1996 Nov; 264(2):390-403. PubMed ID: 8951384
[TBL] [Abstract][Full Text] [Related]
13. Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments.
Nakamura T; Takahashi H; Takahashi M; Shimba N; Suzuki E; Shimada I
J Med Chem; 2010 Mar; 53(5):1917-22. PubMed ID: 20158183
[TBL] [Abstract][Full Text] [Related]
14. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
Menting JG; Ward CW; Margetts MB; Lawrence MC
Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
[TBL] [Abstract][Full Text] [Related]
15. Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
Zhao M; Wan ZL; Whittaker L; Xu B; Phillips NB; Katsoyannis PG; Ismail-Beigi F; Whittaker J; Weiss MA
J Biol Chem; 2009 Nov; 284(46):32178-87. PubMed ID: 19773552
[TBL] [Abstract][Full Text] [Related]
16. The relationship between insulin bioactivity and structure in the NH2-terminal A-chain helix.
Olsen HB; Ludvigsen S; Kaarsholm NC
J Mol Biol; 1998 Nov; 284(2):477-88. PubMed ID: 9813131
[TBL] [Abstract][Full Text] [Related]
17. Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chain.
Nakagawa SH; Zhao M; Hua QX; Hu SQ; Wan ZL; Jia W; Weiss MA
Biochemistry; 2005 Apr; 44(13):4984-99. PubMed ID: 15794637
[TBL] [Abstract][Full Text] [Related]
18. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
Ward CW; Lawrence MC
Bioessays; 2009 Apr; 31(4):422-34. PubMed ID: 19274663
[TBL] [Abstract][Full Text] [Related]
19. Isosteric replacement of A3 Val of porcine insulin by allo-Thr.
Li M; Cui D; Zhang Y
IUBMB Life; 2002 Jan; 53(1):57-60. PubMed ID: 12018409
[TBL] [Abstract][Full Text] [Related]
20. Characterization of a second ligand binding site of the insulin receptor.
Hao C; Whittaker L; Whittaker J
Biochem Biophys Res Commun; 2006 Aug; 347(1):334-9. PubMed ID: 16814253
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
