These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 15611642)

  • 1. HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways.
    Le XF; Pruefer F; Bast RC
    Cell Cycle; 2005 Jan; 4(1):87-95. PubMed ID: 15611642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition.
    Le XF; Claret FX; Lammayot A; Tian L; Deshpande D; LaPushin R; Tari AM; Bast RC
    J Biol Chem; 2003 Jun; 278(26):23441-50. PubMed ID: 12700233
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells.
    Marches R; Uhr JW
    Int J Cancer; 2004 Nov; 112(3):492-501. PubMed ID: 15382077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells.
    Le XF; Arachchige-Don AS; Mao W; Horne MC; Bast RC
    Mol Cancer Ther; 2007 Nov; 6(11):2843-57. PubMed ID: 18025271
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.
    Le XF; Bedrosian I; Mao W; Murray M; Lu Z; Keyomarsi K; Lee MH; Zhao J; Bast RC
    Cell Cycle; 2006 Aug; 5(15):1654-61. PubMed ID: 16861913
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of p27Kip1 in G1 arrest by high dose 5 alpha-dihydrotestosterone in LNCaP human prostate cancer cells.
    Tsihlias J; Zhang W; Bhattacharya N; Flanagan M; Klotz L; Slingerland J
    Oncogene; 2000 Feb; 19(5):670-9. PubMed ID: 10698512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells.
    Lu Y; Zi X; Pollak M
    Int J Cancer; 2004 Jan; 108(3):334-41. PubMed ID: 14648698
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.
    Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL
    Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modulation of p27/Cdk2 complex formation through 4D5-mediated inhibition of HER2 receptor signaling.
    Lane HA; Motoyama AB; Beuvink I; Hynes NE
    Ann Oncol; 2001; 12 Suppl 1():S21-2. PubMed ID: 11521716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor.
    Tseng PH; Wang YC; Weng SC; Weng JR; Chen CS; Brueggemeier RW; Shapiro CL; Chen CY; Dunn SE; Pollak M; Chen CS
    Mol Pharmacol; 2006 Nov; 70(5):1534-41. PubMed ID: 16887935
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of the combined blockade of EGFR and ErbB-2 on signal transduction and regulation of cell cycle regulatory proteins in breast cancer cells.
    D'Alessio A; De Luca A; Maiello MR; Lamura L; Rachiglio AM; Napolitano M; Gallo M; Normanno N
    Breast Cancer Res Treat; 2010 Sep; 123(2):387-96. PubMed ID: 19946741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncology].
    Viallard JF; Lacombe F; Belloc F; Pellegrin JL; Reiffers J
    Cancer Radiother; 2001 Apr; 5(2):109-29. PubMed ID: 11355576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TGF-beta 1 induces the cyclin-dependent kinase inhibitor p27Kip1 mRNA and protein in murine B cells.
    Kamesaki H; Nishizawa K; Michaud GY; Cossman J; Kiyono T
    J Immunol; 1998 Jan; 160(2):770-7. PubMed ID: 9551912
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of action of trastuzumab and scientific update.
    Baselga J; Albanell J; Molina MA; Arribas J
    Semin Oncol; 2001 Oct; 28(5 Suppl 16):4-11. PubMed ID: 11706390
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells.
    Neve RM; Sutterlüty H; Pullen N; Lane HA; Daly JM; Krek W; Hynes NE
    Oncogene; 2000 Mar; 19(13):1647-56. PubMed ID: 10763821
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL; Buffolino P; Kopman C; Nathanson L
    Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens.
    Carroll JS; Swarbrick A; Musgrove EA; Sutherland RL
    Cancer Res; 2002 Jun; 62(11):3126-31. PubMed ID: 12036924
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc.
    Vlach J; Hennecke S; Alevizopoulos K; Conti D; Amati B
    EMBO J; 1996 Dec; 15(23):6595-604. PubMed ID: 8978686
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1).
    Cheng M; Sexl V; Sherr CJ; Roussel MF
    Proc Natl Acad Sci U S A; 1998 Feb; 95(3):1091-6. PubMed ID: 9448290
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.