These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists. Zhao H; Xin Z; Patel JR; Nelson LT; Liu B; Szczepankiewicz BG; Schaefer VG; Falls HD; Kaszubska W; Collins CA; Sham HL; Liu G Bioorg Med Chem Lett; 2005 Apr; 15(7):1825-8. PubMed ID: 15780615 [TBL] [Abstract][Full Text] [Related]
3. 2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists. Serby MD; Zhao H; Szczepankiewicz BG; Kosogof C; Xin Z; Liu B; Liu M; Nelson LT; Kaszubska W; Falls HD; Schaefer V; Bush EN; Shapiro R; Droz BA; Knourek-Segel VE; Fey TA; Brune ME; Beno DW; Turner TM; Collins CA; Jacobson PB; Sham HL; Liu G J Med Chem; 2006 Apr; 49(8):2568-78. PubMed ID: 16610800 [TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists. Xin Z; Zhao H; Serby MD; Liu B; Schaefer VG; Falls DH; Kaszubska W; Colins CA; Sham HL; Liu G Bioorg Med Chem Lett; 2005 Feb; 15(4):1201-4. PubMed ID: 15686942 [TBL] [Abstract][Full Text] [Related]
5. Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists. Xin Z; Serby MD; Zhao H; Kosogof C; Szczepankiewicz BG; Liu M; Liu B; Hutchins CW; Sarris KA; Hoff ED; Falls HD; Lin CW; Ogiela CA; Collins CA; Brune ME; Bush EN; Droz BA; Fey TA; Knourek-Segel VE; Shapiro R; Jacobson PB; Beno DW; Turner TM; Sham HL; Liu G J Med Chem; 2006 Jul; 49(15):4459-69. PubMed ID: 16854051 [TBL] [Abstract][Full Text] [Related]
6. Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration. Liu B; Liu M; Xin Z; Zhao H; Serby MD; Kosogof C; Nelson LT; Szczepankiewicz BG; Kaszubska W; Schaefer VG; Falls HD; Lin CW; Collins CA; Sham HL; Liu G Bioorg Med Chem Lett; 2006 Apr; 16(7):1864-8. PubMed ID: 16442284 [TBL] [Abstract][Full Text] [Related]
8. Growth hormone secretagogue receptor antagonists as anti-obesity therapies? Still an open question. Zhao H; Liu G Curr Opin Drug Discov Devel; 2006 Jul; 9(4):509-15. PubMed ID: 16889233 [TBL] [Abstract][Full Text] [Related]
9. Unacylated ghrelin is not a functional antagonist but a full agonist of the type 1a growth hormone secretagogue receptor (GHS-R). Gauna C; van de Zande B; van Kerkwijk A; Themmen AP; van der Lely AJ; Delhanty PJ Mol Cell Endocrinol; 2007 Aug; 274(1-2):30-4. PubMed ID: 17601657 [TBL] [Abstract][Full Text] [Related]
10. Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR). Zhai W; Flynn N; Longhi DA; Tino JA; Murphy BJ; Slusarchyk D; Gordon DA; Pendri A; Shi S; Stoffel R; Ma B; Sofia MJ; Gerritz SW Bioorg Med Chem Lett; 2008 Sep; 18(18):5083-6. PubMed ID: 18722770 [TBL] [Abstract][Full Text] [Related]
11. Potent achiral agonists of the growth hormone secretagogue (ghrelin) receptor. Part 2: Lead optimisation. Witherington J; Abberley L; Briggs MA; Collis K; Dean DK; Gaiba A; King NP; Kraus H; Shuker N; Steadman JG; Takle AK; Sanger G; Wadsworth G; Butler S; McKay F; Muir A; Winborn K; Heightman TD Bioorg Med Chem Lett; 2008 Mar; 18(6):2203-5. PubMed ID: 18316188 [TBL] [Abstract][Full Text] [Related]
17. Adenosine does not bind to the growth hormone secretagogue receptor type-1a (GHS-R1a). Carreira MC; Camiña JP; Díaz-Rodríguez E; Alvear-Perez R; Llorens-Cortes C; Casanueva FF J Endocrinol; 2006 Oct; 191(1):147-57. PubMed ID: 17065398 [TBL] [Abstract][Full Text] [Related]
18. Characterization of ghrelin receptor activity in a rat pituitary cell line RC-4B/C. Falls HD; Dayton BD; Fry DG; Ogiela CA; Schaefer VG; Brodjian S; Reilly RM; Collins CA; Kaszubska W J Mol Endocrinol; 2006 Aug; 37(1):51-62. PubMed ID: 16901923 [TBL] [Abstract][Full Text] [Related]
19. Urotensin-II receptor antagonists: synthesis and SAR of N-cyclic azaalkyl benzamides. Jin J; An M; Sapienza A; Aiyar N; Naselsky D; Sarau HM; Foley JJ; Salyers KL; Knight SD; Keenan RM; Rivero RA; Dhanak D; Douglas SA Bioorg Med Chem Lett; 2008 Jul; 18(14):3950-4. PubMed ID: 18573659 [TBL] [Abstract][Full Text] [Related]
20. Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands. Bresciani E; Tamiazzo L; Torsello A; Bulgarelli I; Rapetti D; Caporali S; Perrissoud D; Moulin A; Fehrentz JA; Martinez J; Locatelli V Eat Weight Disord; 2008 Sep; 13(3):e67-74. PubMed ID: 19011367 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]