146 related articles for article (PubMed ID: 15615514)
1. Identification of 7-phenylaminothieno- [3,2-b]pyridine-6-carbonitriles as a new class of Src kinase inhibitors.
Boschelli DH; Wu B; Barrios Sosa AC; Durutlic H; Ye F; Raifeld Y; Golas JM; Boschelli F
J Med Chem; 2004 Dec; 47(27):6666-8. PubMed ID: 15615514
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles.
Boschelli DH; Wu B; Barrios Sosa AC; Durutlic H; Chen JJ; Wang Y; Golas JM; Lucas J; Boschelli F
J Med Chem; 2005 Jun; 48(11):3891-902. PubMed ID: 15916442
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and PKCtheta inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles.
Boschelli DH; Wu B; Barrios Sosa AC; Chen J; Asselin M; Cole DC; Lee J; Yang X; Chaudhary D
Bioorg Med Chem Lett; 2008 May; 18(9):2850-3. PubMed ID: 18434148
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles.
Boschelli DH; Wu B; Barrios Sosa AC; Chen JJ; Golas JM; Boschelli F
Bioorg Med Chem Lett; 2005 Nov; 15(21):4681-4. PubMed ID: 16125383
[TBL] [Abstract][Full Text] [Related]
5. 4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonitriles as potent Src kinase inhibitors.
Berger DM; Dutia M; Birnberg G; Powell D; Boschelli DH; Wang YD; Ravi M; Yaczko D; Golas J; Lucas J; Boschelli F
J Med Chem; 2005 Sep; 48(19):5909-20. PubMed ID: 16161995
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and pharmacological evaluation of thieno[2,3-b]pyridine derivatives as novel c-Src inhibitors.
Pevet I; Brulé C; Tizot A; Gohier A; Cruzalegui F; Boutin JA; Goldstein S
Bioorg Med Chem; 2011 Apr; 19(8):2517-28. PubMed ID: 21459579
[TBL] [Abstract][Full Text] [Related]
7. Second generation 4-(4-methyl-1H-indol-5-ylamino)-2-phenylthieno[2,3-b]pyridine-5-carbonitrile PKCtheta inhibitors.
Wu B; Boschelli DH; Lee J; Yang X; Chaudhary D
Bioorg Med Chem Lett; 2009 Feb; 19(3):766-9. PubMed ID: 19111463
[TBL] [Abstract][Full Text] [Related]
8. Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation.
Jaramillo C; de Diego JE; Hamdouchi C; Collins E; Keyser H; Sánchez-Martínez C; del Prado M; Norman B; Brooks HB; Watkins SA; Spencer CD; Dempsey JA; Anderson BD; Campbell RM; Leggett T; Patel B; Schultz RM; Espinosa J; Vieth M; Zhang F; Timm DE
Bioorg Med Chem Lett; 2004 Dec; 14(24):6095-9. PubMed ID: 15546737
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, topoisomerase I inhibition and structure-activity relationship study of 2,4,6-trisubstituted pyridine derivatives.
Zhao LX; Moon YS; Basnet A; Kim EK; Jahng Y; Park JG; Jeong TC; Cho WJ; Choi SU; Lee CO; Lee SY; Lee CS; Lee ES
Bioorg Med Chem Lett; 2004 Mar; 14(5):1333-7. PubMed ID: 14980693
[TBL] [Abstract][Full Text] [Related]
10. Facile preparation of new 4-phenylamino-3-quinolinecarbonitrile Src kinase inhibitors via 7-fluoro intermediates: identification of potent 7-amino analogs.
Boschelli DH; Wu B; Ye F; Durutlic H; Golas JM; Lucas J; Boschelli F
Bioorg Med Chem; 2008 Jan; 16(1):405-12. PubMed ID: 17905586
[TBL] [Abstract][Full Text] [Related]
11. 7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase.
Larsen SD; Zhang Z; DiPaolo BA; Manninen PR; Rohrer DC; Hageman MJ; Hopkins TA; Knechtel ML; Oien NL; Rush BD; Schwende FJ; Stefanski KJ; Wieber JL; Wilkinson KF; Zamora KM; Wathen MW; Brideau RJ
Bioorg Med Chem Lett; 2007 Jul; 17(14):3840-4. PubMed ID: 17513108
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt.
Zhu GD; Gong J; Gandhi VB; Woods K; Luo Y; Liu X; Guan R; Klinghofer V; Johnson EF; Stoll VS; Mamo M; Li Q; Rosenberg SH; Giranda VL
Bioorg Med Chem; 2007 Mar; 15(6):2441-52. PubMed ID: 17258463
[TBL] [Abstract][Full Text] [Related]
13. 7-(aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: addition of water solubilizing groups.
Wu B; Barrios Sosa AC; Boschelli DH; Boschelli F; Honores EE; Golas JM; Powell DW; Wang YD
Bioorg Med Chem Lett; 2006 Aug; 16(15):3993-7. PubMed ID: 16735116
[TBL] [Abstract][Full Text] [Related]
14. 4-Anilino-7-pyridyl-3-quinolinecarbonitriles as Src kinase inhibitors.
Zhang N; Wu B; Boschelli DH; Golas JM; Boschelli F
Bioorg Med Chem Lett; 2009 Sep; 19(17):5071-4. PubMed ID: 19632113
[TBL] [Abstract][Full Text] [Related]
15. Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.
Dalgarno D; Stehle T; Narula S; Schelling P; van Schravendijk MR; Adams S; Andrade L; Keats J; Ram M; Jin L; Grossman T; MacNeil I; Metcalf C; Shakespeare W; Wang Y; Keenan T; Sundaramoorthi R; Bohacek R; Weigele M; Sawyer T
Chem Biol Drug Des; 2006 Jan; 67(1):46-57. PubMed ID: 16492148
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56(Lck) inhibitors.
Chen P; Norris D; Das J; Spergel SH; Wityak J; Leith L; Zhao R; Chen BC; Pitt S; Pang S; Shen DR; Zhang R; De Fex HF; Doweyko AM; McIntyre KW; Shuster DJ; Behnia K; Schieven GL; Barrish JC
Bioorg Med Chem Lett; 2004 Dec; 14(24):6061-6. PubMed ID: 15546730
[TBL] [Abstract][Full Text] [Related]
17. Discovery of thieno[2,3-c]pyridines as potent COT inhibitors.
George D; Friedman M; Allen H; Argiriadi M; Barberis C; Bischoff A; Clabbers A; Cusack K; Dixon R; Fix-Stenzel S; Gordon T; Janssen B; Jia Y; Moskey M; Quinn C; Salmeron JA; Wishart N; Woller K; Yu Z
Bioorg Med Chem Lett; 2008 Sep; 18(18):4952-5. PubMed ID: 18755587
[TBL] [Abstract][Full Text] [Related]
18. Chemical modification and structure-activity relationships of pyripyropenes. 3. Synthetic conversion of pyridine-pyrone moiety.
Obata R; Sunazuka T; Tian Z; Tomoda H; Harigaya Y; Omura S
J Antibiot (Tokyo); 1997 Mar; 50(3):229-36. PubMed ID: 9127194
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of 3,7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR.
Wu Z; Fraley ME; Bilodeau MT; Kaufman ML; Tasber ES; Balitza AE; Hartman GD; Coll KE; Rickert K; Shipman J; Shi B; Sepp-Lorenzino L; Thomas KA
Bioorg Med Chem Lett; 2004 Feb; 14(4):909-12. PubMed ID: 15012992
[TBL] [Abstract][Full Text] [Related]
20. 2-Trifluoroacetylthiophenes, a novel series of potent and selective class II histone deacetylase inhibitors.
Jones P; Bottomley MJ; Carfí A; Cecchetti O; Ferrigno F; Lo Surdo P; Ontoria JM; Rowley M; Scarpelli R; Schultz-Fademrecht C; Steinkühler C
Bioorg Med Chem Lett; 2008 Jun; 18(11):3456-61. PubMed ID: 18440229
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]