BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

99 related articles for article (PubMed ID: 15619241)

  • 1. Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.
    Uppal H; Toma D; Saini SP; Ren S; Jones TJ; Xie W
    Hepatology; 2005 Jan; 41(1):168-76. PubMed ID: 15619241
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
    Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
    Stedman CA; Liddle C; Coulter SA; Sonoda J; Alvarez JG; Moore DD; Evans RM; Downes M
    Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2063-8. PubMed ID: 15684063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice.
    Teng S; Piquette-Miller M
    J Pharmacol Exp Ther; 2005 Feb; 312(2):841-8. PubMed ID: 15456840
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinate regulation of xenobiotic and bile acid homeostasis by pregnane X receptor.
    Staudinger J; Liu Y; Madan A; Habeebu S; Klaassen CD
    Drug Metab Dispos; 2001 Nov; 29(11):1467-72. PubMed ID: 11602523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.
    Saini SP; Sonoda J; Xu L; Toma D; Uppal H; Mu Y; Ren S; Moore DD; Evans RM; Xie W
    Mol Pharmacol; 2004 Feb; 65(2):292-300. PubMed ID: 14742670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S; Huang W; Staudinger JL; Tan K; Cole TJ; Moore DD; Strobel HW
    Drug Metab Dispos; 2007 Jan; 35(1):36-42. PubMed ID: 17020958
    [TBL] [Abstract][Full Text] [Related]  

  • 8. P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
    Waxman DJ
    Arch Biochem Biophys; 1999 Sep; 369(1):11-23. PubMed ID: 10462436
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A; Looser R; Kaufmann M; Blättler SM; Rencurel F; Huang W; Moore DD; Meyer UA
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of hepatic drug metabolism: role of the nuclear receptors PXR and CAR.
    Liddle C; Goodwin B
    Semin Liver Dis; 2002; 22(2):115-22. PubMed ID: 12016543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.
    Saini SP; Mu Y; Gong H; Toma D; Uppal H; Ren S; Li S; Poloyac SM; Xie W
    Hepatology; 2005 Mar; 41(3):497-505. PubMed ID: 15726644
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pregnane X receptor (PXR) deficiency improves high fat diet-induced obesity via induction of fibroblast growth factor 15 (FGF15) expression.
    Zhao LY; Xu JY; Shi Z; Englert NA; Zhang SY
    Biochem Pharmacol; 2017 Oct; 142():194-203. PubMed ID: 28756207
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response.
    Kim MS; Shigenaga J; Moser A; Grunfeld C; Feingold KR
    Am J Physiol Endocrinol Metab; 2004 Oct; 287(4):E731-8. PubMed ID: 15198932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
    Anakk S; Kalsotra A; Kikuta Y; Huang W; Zhang J; Staudinger JL; Moore DD; Strobel HW
    Pharmacogenomics J; 2004; 4(2):91-101. PubMed ID: 14770174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver.
    Kiyosawa N; Kwekel JC; Burgoon LD; Williams KJ; Tashiro C; Chittim B; Zacharewski TR
    Toxicol Sci; 2008 Feb; 101(2):350-63. PubMed ID: 17984292
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response.
    Beigneux AP; Moser AH; Shigenaga JK; Grunfeld C; Feingold KR
    Biochem Biophys Res Commun; 2002 Apr; 293(1):145-9. PubMed ID: 12054576
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Microarray-based compendium of hepatic gene expression profiles for prototypical ADME gene-inducing compounds in rats and mice in vivo.
    Slatter JG; Cheng O; Cornwell PD; de Souza A; Rockett J; Rushmore T; Hartley D; Evers R; He Y; Dai X; Hu R; Caguyong M; Roberts CJ; Castle J; Ulrich RG
    Xenobiotica; 2006; 36(10-11):902-37. PubMed ID: 17118914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bile acid-activated receptors in the treatment of dyslipidemia and related disorders.
    Fiorucci S; Cipriani S; Baldelli F; Mencarelli A
    Prog Lipid Res; 2010 Apr; 49(2):171-85. PubMed ID: 19932133
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PXR and CAR in energy metabolism.
    Wada T; Gao J; Xie W
    Trends Endocrinol Metab; 2009 Aug; 20(6):273-9. PubMed ID: 19595610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver.
    Xu DX; Wei W; Sun MF; Wu CY; Wang JP; Wei LZ; Zhou CF
    Free Radic Biol Med; 2004 Jul; 37(1):10-22. PubMed ID: 15183191
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.