729 related articles for article (PubMed ID: 15625077)
1. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
[TBL] [Abstract][Full Text] [Related]
2. Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs.
Roudier E; Mistafa O; Stenius U
Mol Cancer Ther; 2006 Nov; 5(11):2706-15. PubMed ID: 17121917
[TBL] [Abstract][Full Text] [Related]
3. TCDD activates Mdm2 and attenuates the p53 response to DNA damaging agents.
Pääjärvi G; Viluksela M; Pohjanvirta R; Stenius U; Högberg J
Carcinogenesis; 2005 Jan; 26(1):201-8. PubMed ID: 15459018
[TBL] [Abstract][Full Text] [Related]
4. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
[TBL] [Abstract][Full Text] [Related]
5. Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.
Nakao T; Shiota M; Tatemoto Y; Izumi Y; Iwao H
J Pharmacol Sci; 2007 Dec; 105(4):334-41. PubMed ID: 18057776
[TBL] [Abstract][Full Text] [Related]
6. Akt enhances Mdm2-mediated ubiquitination and degradation of p53.
Ogawara Y; Kishishita S; Obata T; Isazawa Y; Suzuki T; Tanaka K; Masuyama N; Gotoh Y
J Biol Chem; 2002 Jun; 277(24):21843-50. PubMed ID: 11923280
[TBL] [Abstract][Full Text] [Related]
7. Reduced ATM kinase activity and an attenuated p53 response to DNA damage in carcinogen-induced preneoplastic hepatic lesions in the rat.
Silins I; Finnberg N; Ståhl A; Högberg J; Stenius U
Carcinogenesis; 2001 Dec; 22(12):2023-31. PubMed ID: 11751435
[TBL] [Abstract][Full Text] [Related]
8. Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.
Burch LR; Scott M; Pohler E; Meek D; Hupp T
J Mol Biol; 2004 Mar; 337(1):115-28. PubMed ID: 15001356
[TBL] [Abstract][Full Text] [Related]
9. Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells.
Bhattacharya S; Ray RM; Johnson LR
Cell Signal; 2009 Apr; 21(4):509-22. PubMed ID: 19136059
[TBL] [Abstract][Full Text] [Related]
10. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.
Zhou BP; Liao Y; Xia W; Zou Y; Spohn B; Hung MC
Nat Cell Biol; 2001 Nov; 3(11):973-82. PubMed ID: 11715018
[TBL] [Abstract][Full Text] [Related]
11. Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions.
Finnberg N; Silins I; Stenius U; Högberg J
Carcinogenesis; 2004 Jan; 25(1):113-22. PubMed ID: 14555611
[TBL] [Abstract][Full Text] [Related]
12. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
13. Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.
Shinozaki T; Nota A; Taya Y; Okamoto K
Oncogene; 2003 Dec; 22(55):8870-80. PubMed ID: 14654783
[TBL] [Abstract][Full Text] [Related]
14. Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents.
Mujoo K; Watanabe M; Nakamura J; Khokhar AR; Siddik ZH
J Cancer Res Clin Oncol; 2003 Dec; 129(12):709-18. PubMed ID: 14513366
[TBL] [Abstract][Full Text] [Related]
15. Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors.
Kubota T; Fujisaki K; Itoh Y; Yano T; Sendo T; Oishi R
Biochem Pharmacol; 2004 Jun; 67(12):2175-86. PubMed ID: 15163549
[TBL] [Abstract][Full Text] [Related]
16. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.
Kulikov R; Boehme KA; Blattner C
Mol Cell Biol; 2005 Aug; 25(16):7170-80. PubMed ID: 16055726
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
[TBL] [Abstract][Full Text] [Related]
18. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
[TBL] [Abstract][Full Text] [Related]
19. Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo.
Van Gijssel HE; Ohlson LC; Torndal UB; Mulder GJ; Eriksson LC; Porsch-Hällström I; Meerman JH
Hepatology; 2000 Oct; 32(4 Pt 1):701-10. PubMed ID: 11003613
[TBL] [Abstract][Full Text] [Related]
20. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells.
Yang Y; Ludwig RL; Jensen JP; Pierre SA; Medaglia MV; Davydov IV; Safiran YJ; Oberoi P; Kenten JH; Phillips AC; Weissman AM; Vousden KH
Cancer Cell; 2005 Jun; 7(6):547-59. PubMed ID: 15950904
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
