These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 15626750)

  • 1. Pharmacological differences between human and guinea pig histamine H1 receptors: Asn84 (2.61) as key residue within an additional binding pocket in the H1 receptor.
    Bruysters M; Jongejan A; Gillard M; van de Manakker F; Bakker RA; Chatelain P; Leurs R
    Mol Pharmacol; 2005 Apr; 67(4):1045-52. PubMed ID: 15626750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
    Strasser A; Striegl B; Wittmann HJ; Seifert R
    J Pharmacol Exp Ther; 2008 Jan; 324(1):60-71. PubMed ID: 17928567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor.
    Strasser A; Wittmann HJ; Kunze M; Elz S; Seifert R
    Mol Pharmacol; 2009 Mar; 75(3):454-65. PubMed ID: 19047480
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H(1)-receptor.
    Wittmann HJ; Seifert R; Strasser A
    Mol Pharmacol; 2009 Jul; 76(1):25-37. PubMed ID: 19346300
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.
    Bruysters M; Pertz HH; Teunissen A; Bakker RA; Gillard M; Chatelain P; Schunack W; Timmerman H; Leurs R
    Eur J Pharmacol; 2004 Mar; 487(1-3):55-63. PubMed ID: 15033376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
    Wittmann HJ; Seifert R; Strasser A
    Biochem Pharmacol; 2011 Dec; 82(12):1910-8. PubMed ID: 21933664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand-specific contribution of the N terminus and E2-loop to pharmacological properties of the histamine H1-receptor.
    Strasser A; Wittmann HJ; Seifert R
    J Pharmacol Exp Ther; 2008 Sep; 326(3):783-91. PubMed ID: 18577700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of impromidine- and arpromidine-derived guanidines on recombinant human and guinea pig histamine H1 and H2 receptors.
    Xie SX; Schalkhausser F; Ye QZ; Seifert R; Buschauer A
    Arch Pharm (Weinheim); 2007 Jan; 340(1):9-16. PubMed ID: 17206612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor.
    Seifert R; Wenzel-Seifert K; Burckstummer T; Pertz HH; Schunack W; Dove S; Buschauer A; Elz S
    J Pharmacol Exp Ther; 2003 Jun; 305(3):1104-15. PubMed ID: 12626648
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines.
    Xie SX; Ghorai P; Ye QZ; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2006 Apr; 317(1):139-46. PubMed ID: 16394198
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor.
    Deml KF; Beermann S; Neumann D; Strasser A; Seifert R
    Mol Pharmacol; 2009 Nov; 76(5):1019-30. PubMed ID: 19720730
    [TBL] [Abstract][Full Text] [Related]  

  • 12. N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors.
    Xie SX; Kraus A; Ghorai P; Ye QZ; Elz S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1262-8. PubMed ID: 16554355
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular determinants of ligand binding to H4R species variants.
    Lim HD; de Graaf C; Jiang W; Sadek P; McGovern PM; Istyastono EP; Bakker RA; de Esch IJ; Thurmond RL; Leurs R
    Mol Pharmacol; 2010 May; 77(5):734-43. PubMed ID: 20103609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors.
    Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2007 Jun; 321(3):983-95. PubMed ID: 17332265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Linking agonist binding to histamine H1 receptor activation.
    Jongejan A; Bruysters M; Ballesteros JA; Haaksma E; Bakker RA; Pardo L; Leurs R
    Nat Chem Biol; 2005 Jul; 1(2):98-103. PubMed ID: 16408006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity.
    Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
    J Pharmacol Exp Ther; 2007 Jun; 321(3):975-82. PubMed ID: 17347323
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Delineation of receptor-ligand interactions at the human histamine H1 receptor by a combined approach of site-directed mutagenesis and computational techniques - or - how to bind the H1 receptor.
    Jongejan A; Leurs R
    Arch Pharm (Weinheim); 2005 Jun; 338(5-6):248-59. PubMed ID: 15952243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Homology modelling and binding site mapping of the human histamine H1 receptor.
    Kiss R; Kovári Z; Keseru GM
    Eur J Med Chem; 2004 Nov; 39(11):959-67. PubMed ID: 15501545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Side-chain modified analogues of histaprodifen: asymmetric synthesis and histamine H1-receptor activity.
    Patil R; Elz S; Reiser O
    Bioorg Med Chem Lett; 2006 Feb; 16(3):672-6. PubMed ID: 16266803
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N(alpha)-imidazolylalkyl and pyridylalkyl derivatives of histaprodifen: synthesis and in vitro evaluation of highly potent histamine H(1)-receptor agonists.
    Menghin S; Pertz HH; Kramer K; Seifert R; Schunack W; Elz S
    J Med Chem; 2003 Dec; 46(25):5458-70. PubMed ID: 14640554
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.