These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 15632059)

  • 1. Chk1-dependent S-M checkpoint delay in vertebrate cells is linked to maintenance of viable replication structures.
    Zachos G; Rainey MD; Gillespie DA
    Mol Cell Biol; 2005 Jan; 25(2):563-74. PubMed ID: 15632059
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
    Guo N; Faller DV; Vaziri C
    Cell Growth Differ; 2002 Feb; 13(2):77-86. PubMed ID: 11864911
    [TBL] [Abstract][Full Text] [Related]  

  • 3. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
    Yu Q; La Rose J; Zhang H; Takemura H; Kohn KW; Pommier Y
    Cancer Res; 2002 Oct; 62(20):5743-8. PubMed ID: 12384533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing.
    Feijoo C; Hall-Jackson C; Wu R; Jenkins D; Leitch J; Gilbert DM; Smythe C
    J Cell Biol; 2001 Sep; 154(5):913-23. PubMed ID: 11535615
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.
    Rainey MD; Black EJ; Zachos G; Gillespie DA
    Oncogene; 2008 Feb; 27(7):896-906. PubMed ID: 17684483
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of Cdc2/cyclin B activation in Xenopus egg extracts via inhibitory phosphorylation of Cdc25C phosphatase by Ca(2+)/calmodulin-dependent protein [corrected] kinase II.
    Hutchins JR; Dikovskaya D; Clarke PR
    Mol Biol Cell; 2003 Oct; 14(10):4003-14. PubMed ID: 14517314
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA damage control: regulation and functions of checkpoint kinase 1.
    Smits VA; Gillespie DA
    FEBS J; 2015 Oct; 282(19):3681-92. PubMed ID: 26216057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
    Varmark H; Kwak S; Theurkauf WE
    Cell Cycle; 2010 Jan; 9(2):312-20. PubMed ID: 20023427
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p53-dependent Chk1 phosphorylation is required for maintenance of prolonged G2 Arrest.
    Wang XQ; Stanbridge EJ; Lao X; Cai Q; Fan ST; Redpath JL
    Radiat Res; 2007 Dec; 168(6):706-15. PubMed ID: 18088187
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1.
    Clay-Farrace L; Pelizon C; Santamaria D; Pines J; Laskey RA
    EMBO J; 2003 Feb; 22(3):704-12. PubMed ID: 12554670
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cdk phosphorylation of Chk1 regulates efficient Chk1 activation and multiple checkpoint proficiency.
    Xu N; Libertini S; Zhang Y; Gillespie DA
    Biochem Biophys Res Commun; 2011 Sep; 413(3):465-70. PubMed ID: 21907702
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.
    den Elzen NR; O'Connell MJ
    EMBO J; 2004 Feb; 23(4):908-18. PubMed ID: 14765108
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1).
    Shiromizu T; Goto H; Tomono Y; Bartek J; Totsukawa G; Inoko A; Nakanishi M; Matsumura F; Inagaki M
    Genes Cells; 2006 May; 11(5):477-85. PubMed ID: 16629900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects.
    Zachos G; Rainey MD; Gillespie DA
    EMBO J; 2003 Feb; 22(3):713-23. PubMed ID: 12554671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chk1 instability is coupled to mitotic cell death of p53-deficient cells in response to virus-induced DNA damage signaling.
    Jurvansuu J; Fragkos M; Ingemarsdotter C; Beard P
    J Mol Biol; 2007 Sep; 372(2):397-406. PubMed ID: 17663993
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
    Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Negative regulation of mitotic promoting factor by the checkpoint kinase chk1 in simian virus 40 lytic infection.
    Okubo E; Lehman JM; Friedrich TD
    J Virol; 2003 Jan; 77(2):1257-67. PubMed ID: 12502843
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation.
    Liu X; Guo Y; Li Y; Jiang Y; Chubb S; Azuma A; Huang P; Matsuda A; Hittelman W; Plunkett W
    Cancer Res; 2005 Aug; 65(15):6874-81. PubMed ID: 16061671
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B.
    Zuazua-Villar P; Rodriguez R; Gagou ME; Eyers PA; Meuth M
    Cell Death Dis; 2014 May; 5(5):e1253. PubMed ID: 24853431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.