BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 15632084)

  • 1. Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation.
    Marchetti S; Gimond C; Chambard JC; Touboul T; Roux D; Pouysségur J; Pagès G
    Mol Cell Biol; 2005 Jan; 25(2):854-64. PubMed ID: 15632084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein kinase Cdelta-mediated proteasomal degradation of MAP kinase phosphatase-1 contributes to glutamate-induced neuronal cell death.
    Choi BH; Hur EM; Lee JH; Jun DJ; Kim KT
    J Cell Sci; 2006 Apr; 119(Pt 7):1329-40. PubMed ID: 16537649
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation.
    Hutter D; Chen P; Barnes J; Liu Y
    Biochem J; 2000 Nov; 352 Pt 1(Pt 1):155-63. PubMed ID: 11062068
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inducible expression of a MAP kinase phosphatase-3-GFP chimera specifically blunts fibroblast growth and ras-dependent tumor formation in nude mice.
    Marchetti S; Gimond C; Roux D; Gothié E; Pouysségur J; Pagès G
    J Cell Physiol; 2004 Jun; 199(3):441-50. PubMed ID: 15095291
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.
    Sarközi R; Miller B; Pollack V; Feifel E; Mayer G; Sorokin A; Schramek H
    J Cell Physiol; 2007 Apr; 211(1):88-100. PubMed ID: 17131384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
    Bardwell AJ; Abdollahi M; Bardwell L
    Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically.
    Chen P; Hutter D; Yang X; Gorospe M; Davis RJ; Liu Y
    J Biol Chem; 2001 Aug; 276(31):29440-9. PubMed ID: 11387337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1.
    Kassel O; Sancono A; Krätzschmar J; Kreft B; Stassen M; Cato AC
    EMBO J; 2001 Dec; 20(24):7108-16. PubMed ID: 11742987
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1.
    Slack DN; Seternes OM; Gabrielsen M; Keyse SM
    J Biol Chem; 2001 May; 276(19):16491-500. PubMed ID: 11278799
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP.
    Pettiford SM; Herbst R
    Oncogene; 2000 Feb; 19(7):858-69. PubMed ID: 10702794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells.
    Chen TH; Kao YC; Chen BC; Chen CH; Chan P; Lee HM
    Eur J Pharmacol; 2006 Jul; 541(3):138-46. PubMed ID: 16765938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The antiproliferative effect of sildenafil on pulmonary artery smooth muscle cells is mediated via upregulation of mitogen-activated protein kinase phosphatase-1 and degradation of extracellular signal-regulated kinase 1/2 phosphorylation.
    Li B; Yang L; Shen J; Wang C; Jiang Z
    Anesth Analg; 2007 Oct; 105(4):1034-41, table of contents. PubMed ID: 17898384
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.
    Groom LA; Sneddon AA; Alessi DR; Dowd S; Keyse SM
    EMBO J; 1996 Jul; 15(14):3621-32. PubMed ID: 8670865
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD40-modulated dual-specificity phosphatases MAPK phosphatase (MKP)-1 and MKP-3 reciprocally regulate Leishmania major infection.
    Srivastava N; Sudan R; Saha B
    J Immunol; 2011 May; 186(10):5863-72. PubMed ID: 21471446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf.
    Marzec M; Kasprzycka M; Liu X; Raghunath PN; Wlodarski P; Wasik MA
    Oncogene; 2007 Feb; 26(6):813-21. PubMed ID: 16909118
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1.
    Tárrega C; Ríos P; Cejudo-Marín R; Blanco-Aparicio C; van den Berk L; Schepens J; Hendriks W; Tabernero L; Pulido R
    J Biol Chem; 2005 Nov; 280(45):37885-94. PubMed ID: 16148006
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1.
    Ward Y; Gupta S; Jensen P; Wartmann M; Davis RJ; Kelly K
    Nature; 1994 Feb; 367(6464):651-4. PubMed ID: 8107850
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mitogen-activated protein kinase phosphatase-3 N-terminal noncatalytic region is responsible for tight substrate binding and enzymatic specificity.
    Muda M; Theodosiou A; Gillieron C; Smith A; Chabert C; Camps M; Boschert U; Rodrigues N; Davies K; Ashworth A; Arkinstall S
    J Biol Chem; 1998 Apr; 273(15):9323-9. PubMed ID: 9535927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
    Ekerot M; Stavridis MP; Delavaine L; Mitchell MP; Staples C; Owens DM; Keenan ID; Dickinson RJ; Storey KG; Keyse SM
    Biochem J; 2008 Jun; 412(2):287-98. PubMed ID: 18321244
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase.
    Camps M; Nichols A; Gillieron C; Antonsson B; Muda M; Chabert C; Boschert U; Arkinstall S
    Science; 1998 May; 280(5367):1262-5. PubMed ID: 9596579
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.