392 related articles for article (PubMed ID: 15634005)
1. Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Clement O; Shoemaker R; Sei S; Neamati N
J Med Chem; 2005 Jan; 48(1):111-20. PubMed ID: 15634005
[TBL] [Abstract][Full Text] [Related]
2. Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
Dayam R; Sanchez T; Neamati N
J Med Chem; 2005 Dec; 48(25):8009-15. PubMed ID: 16335925
[TBL] [Abstract][Full Text] [Related]
3. Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.
Barreca ML; Ferro S; Rao A; De Luca L; Zappalà M; Monforte AM; Debyser Z; Witvrouw M; Chimirri A
J Med Chem; 2005 Nov; 48(22):7084-8. PubMed ID: 16250669
[TBL] [Abstract][Full Text] [Related]
4. Discovery of HIV-1 integrase inhibitors by pharmacophore searching.
Hong H; Neamati N; Wang S; Nicklaus MC; Mazumder A; Zhao H; Burke TR; Pommier Y; Milne GW
J Med Chem; 1997 Mar; 40(6):930-6. PubMed ID: 9083481
[TBL] [Abstract][Full Text] [Related]
5. Efficient 3D database screening for novel HIV-1 IN inhibitors.
Barreca ML; Rao A; De Luca L; Zappalà M; Gurnari C; Monforte P; De Clercq E; Van Maele B; Debyser Z; Witvrouw M; Briggs JM; Chimirri A
J Chem Inf Comput Sci; 2004; 44(4):1450-5. PubMed ID: 15272853
[TBL] [Abstract][Full Text] [Related]
6. Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
Neamati N; Hong H; Mazumder A; Wang S; Sunder S; Nicklaus MC; Milne GW; Proksa B; Pommier Y
J Med Chem; 1997 Mar; 40(6):942-51. PubMed ID: 9083483
[TBL] [Abstract][Full Text] [Related]
7. Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.
Deng J; Kelley JA; Barchi JJ; Sanchez T; Dayam R; Pommier Y; Neamati N
Bioorg Med Chem; 2006 Jun; 14(11):3785-92. PubMed ID: 16460953
[TBL] [Abstract][Full Text] [Related]
8. Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
Deng J; Sanchez T; Al-Mawsawi LQ; Dayam R; Yunes RA; Garofalo A; Bolger MB; Neamati N
Bioorg Med Chem; 2007 Jul; 15(14):4985-5002. PubMed ID: 17502148
[TBL] [Abstract][Full Text] [Related]
9. Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.
Rajamaki S; Innitzer A; Falciani C; Tintori C; Christ F; Witvrouw M; Debyser Z; Massa S; Botta M
Bioorg Med Chem Lett; 2009 Jul; 19(13):3615-8. PubMed ID: 19447621
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.
Sechi M; Derudas M; Dallocchio R; Dessì A; Bacchi A; Sannia L; Carta F; Palomba M; Ragab O; Chan C; Shoemaker R; Sei S; Dayam R; Neamati N
J Med Chem; 2004 Oct; 47(21):5298-310. PubMed ID: 15456274
[TBL] [Abstract][Full Text] [Related]
11. HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
Nicklaus MC; Neamati N; Hong H; Mazumder A; Sunder S; Chen J; Milne GW; Pommier Y
J Med Chem; 1997 Mar; 40(6):920-9. PubMed ID: 9083480
[TBL] [Abstract][Full Text] [Related]
12. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
13. Discovery and structure-activity relationship studies of a unique class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Neamati N
ChemMedChem; 2006 Feb; 1(2):238-44. PubMed ID: 16892356
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
Vandurm P; Guiguen A; Cauvin C; Georges B; Le Van K; Michaux C; Cardona C; Mbemba G; Mouscadet JF; Hevesi L; Van Lint C; Wouters J
Eur J Med Chem; 2011 May; 46(5):1749-56. PubMed ID: 21385662
[TBL] [Abstract][Full Text] [Related]
15. Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
Artico M; Di Santo R; Costi R; Novellino E; Greco G; Massa S; Tramontano E; Marongiu ME; De Montis A; La Colla P
J Med Chem; 1998 Oct; 41(21):3948-60. PubMed ID: 9767632
[TBL] [Abstract][Full Text] [Related]
16. Hydrazide-containing inhibitors of HIV-1 integrase.
Zhao H; Neamati N; Sunder S; Hong H; Wang S; Milne GW; Pommier Y; Burke TR
J Med Chem; 1997 Mar; 40(6):937-41. PubMed ID: 9083482
[TBL] [Abstract][Full Text] [Related]
17. Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.
Grobler JA; Stillmock K; Hu B; Witmer M; Felock P; Espeseth AS; Wolfe A; Egbertson M; Bourgeois M; Melamed J; Wai JS; Young S; Vacca J; Hazuda DJ
Proc Natl Acad Sci U S A; 2002 May; 99(10):6661-6. PubMed ID: 11997448
[TBL] [Abstract][Full Text] [Related]
18. Salicylhydrazine-containing inhibitors of HIV-1 integrase: implication for a selective chelation in the integrase active site.
Neamati N; Hong H; Owen JM; Sunder S; Winslow HE; Christensen JL; Zhao H; Burke TR; Milne GW; Pommier Y
J Med Chem; 1998 Aug; 41(17):3202-9. PubMed ID: 9703465
[TBL] [Abstract][Full Text] [Related]
19. HIV integrase as a target for antiviral chemotherapy.
Nair V
Rev Med Virol; 2002; 12(3):179-93. PubMed ID: 11987143
[TBL] [Abstract][Full Text] [Related]
20. Conformationally restrained carbazolone-containing alpha,gamma-diketo acids as inhibitors of HIV integrase.
Li X; Vince R
Bioorg Med Chem; 2006 May; 14(9):2942-55. PubMed ID: 16386908
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
